<i>Rhodococcus</i> spp. interacts with human norovirus in clinical samples and impairs its replication on human intestinal enteroids. [PDF]
Santiso-Bellón C+11 more
europepmc +1 more source
Particle‐Assisted Optoelectronic Tweezers for Manipulating Single Cells and Microparticles
This work introduces a particle‐assisted optoelectronic tweezers (OET) technique that uses Ag‐SiO2 microparticles as intermediaries to manipulate cells and microparticles via particle‐induced dielectrophoresis. The method extends the OET manipulation range while reducing cell damage.
Ao Wang+13 more
wiley +1 more source
Investigation of the effect of anti-PIA/PNAG antibodies on biofilm formation in <i>Escherichia coli</i>. [PDF]
Shirmohammadpour M+5 more
europepmc +1 more source
A novel microphysiological system that can mimic sterile or non‐sterile injury demonstrates that macrophage‐derived extracellular vesicles modulate neutrophil migratory responses to these different wound states. The model showed that resolution of inflammation through neutrophil reverse migration is driven by IL‐8 derived from extracellular vesicles ...
Kehinde Adebayo Babatunde+5 more
wiley +1 more source
FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity
Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li+11 more
wiley +1 more source
Immunoassay-mass spectrometry to identify <i>Brucella melitensis</i>. [PDF]
Sharif A, Nejad RB, Ghassempour A.
europepmc +1 more source
The study identified sortilin as a promising LTR, enabling targeted degradation of oncogenic proteins through an mRNA‐encoded MedTAC strategy. In a mouse model, MedTACPTK7 reduced PTK7 by up to 80%, extended survival, and showed excellent pharmacokinetics without toxicity, providing a scalable platform for targeted therapies.
Xin Chang+8 more
wiley +1 more source
Indirect ELISA developed to detect antibodies against Mycoplasma synoviae P50 protein via immunoproteomic screening. [PDF]
Liu Y+7 more
europepmc +1 more source
Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague
The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia+12 more
wiley +1 more source
Develop an indirect ELISA utilizing gD protein to detect antibodies against bovine herpesvirus type 1. [PDF]
Liu Q+10 more
europepmc +1 more source