Results 271 to 280 of about 3,053,812 (327)

Isolation of human monoclonal antibodies from 4CMenB vaccinees reveals PorB and LOS as the main OMV components inducing cross-strain protection. [PDF]

Front Immunol
Vezzani G, Viviani V, Audagnotto M, Rossi A, Cinelli P, Pacchiani N, Limongi C, Santini L, Giusti F, Tomei S, Torricelli G, Faenzi E, Sammicheli C, Tavarini S, Efron A, Biolchi A, Finco O, Delany I, Frigimelica E.   +18 more
europepmc   +1 more source

Host-Pathogen Interaction Interface: Promising Candidate Targets for Vaccine-Induced Protective and Memory Immune Responses. [PDF]

Vaccines (Basel)
Guerrero GG, Madrid-Marina V, Martínez-Romero A, Torres-Poveda K, Favela-Hernández JM.   +4 more
europepmc   +1 more source

Antibodies with specificity to glycan motifs that decorate OMV cargo proteins. [PDF]

mSphere
Kim HY, Rothenberger CM, Davey ME, Yu M.
europepmc   +1 more source

Current Challenges in <i>Yersinia</i> Diagnosis and Treatment. [PDF]

Microorganisms
Grygiel-Górniak B.
europepmc   +1 more source

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Anti-bacterial Monoclonal Antibodies

Advances in Experimental Medicine and Biology, 2017
The failing efficacy of antibiotics and the high mortality rate among high-risk patients calls for new treatment modalities for bacterial infections. Due to the vastly divergent pathogenesis of human pathogens, each microbe requires a tailored approach.
Eszter Nagy, Christine A. Power, Valéria Szijártó, Gabor Nagy, Adriana Badarau   +4 more
openaire   +4 more sources

Anti-bacterial monoclonal antibodies: Back to the future?

Archives of Biochemistry and Biophysics, 2012
Today's medicine has to deal with the emergence of multi-drug resistant bacteria, and is beginning to be confronted with pan-resistant microbes. This worsening inadequacy of the antibiotics concept, which has ruled infectious medicine in the last six decades creates an increasing unmet medical need that can be addressed by passive immunization.
Gabor Nagy, Eszter Nagy, Martin B. Oleksiewicz   +2 more
openaire   +3 more sources

Site‐Specific and Stoichiometric Modification of Antibodies by Bacterial Transglutaminase

Angewandte Chemie International Edition, 2010
The therapeutic efficacy of antibodies can be substantially enhanced by conjugation of cytotoxic compounds such as chemotherapeutics and particle-emitting radionuclides. Intuitively one would assume that the therapeutic index would improve as the number of cytotoxic entities conjugated to the antibody increases.
Jeger, S, Zimmermann, K, Blanc, A, Grünberg, J, Honer, M, Hunziker, P, Struthers, H, Schibli, R   +7 more
openaire   +3 more sources