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Strategic Advances in Targeted Delivery Carriers for Therapeutic Cancer Vaccines. [PDF]
Int J Mol SciWu J +7 more
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Anti-bacterial Monoclonal Antibodies.
Advances in Experimental Medicine and Biology, 2017The failing efficacy of antibiotics and the high mortality rate among high-risk patients calls for new treatment modalities for bacterial infections. Due to the vastly divergent pathogenesis of human pathogens, each microbe requires a tailored approach.
E. Nagy +4 more
semanticscholar +4 more sources
Anti-bacterial monoclonal antibodies: back to the future?
Archives of Biochemistry and Biophysics, 2012Today's medicine has to deal with the emergence of multi-drug resistant bacteria, and is beginning to be confronted with pan-resistant microbes. This worsening inadequacy of the antibiotics concept, which has ruled infectious medicine in the last six decades creates an increasing unmet medical need that can be addressed by passive immunization.
M. B. Oleksiewicz, G. Nagy, E. Nagy
semanticscholar +3 more sources
Site-specific and stoichiometric modification of antibodies by bacterial transglutaminase.
Angewandte Chemie International Edition, 2010The therapeutic efficacy of antibodies can be substantially enhanced by conjugation of cytotoxic compounds such as chemotherapeutics and particle-emitting radionuclides.
Simone Jeger +7 more
semanticscholar +3 more sources
Antibodies and Immunoassays for Detection of Bacterial Pathogens
, 2008Antibody, also known as immunoglobulin, is normally made in the body in defense of foreign antigen or invading pathogen. Highly specific biorecognition property of antibody with antigen has made antibody as one of the most indispensable molecules for broad application, not only in the diagnosis or detection but also in prevention or curing of diseases.
P. Banada, A. Bhunia
semanticscholar +3 more sources
Protein Engineering, 1993
In order to achieve a stable and functional immobilization of antibodies, we investigated the possibility of adding hydrophobic membrane anchors to antibody fragments expressed in Escherichia coli.
M. Laukkanen, T. Teeri, Kari Keinänen
semanticscholar +1 more source
In order to achieve a stable and functional immobilization of antibodies, we investigated the possibility of adding hydrophobic membrane anchors to antibody fragments expressed in Escherichia coli.
M. Laukkanen, T. Teeri, Kari Keinänen
semanticscholar +1 more source
Journal of Immunological Methods, 2022
The indirect enzyme-linked immunosorbent assay (ELISA) is the gold standard method for monoclonal antibody (McAb) detection and plays a unique role in the preparation of bacterial antibodies. To solve the laborious issues associated with indirect ELISA, a novel bacterial coloration immunofluorescence strip (BCIFS) for antibody detection using colored ...
Shuiqin, Fang +6 more
openaire +2 more sources
The indirect enzyme-linked immunosorbent assay (ELISA) is the gold standard method for monoclonal antibody (McAb) detection and plays a unique role in the preparation of bacterial antibodies. To solve the laborious issues associated with indirect ELISA, a novel bacterial coloration immunofluorescence strip (BCIFS) for antibody detection using colored ...
Shuiqin, Fang +6 more
openaire +2 more sources
Modified Bacterial Outer Membrane Vesicles Induce Autoantibodies for Tumor Therapy
Acta Biomaterialia, 2020Using monoclonal antibodies to block tumor angiogenesis has yielded effective antitumor effects. However, this treatment method has long cycles and is very expensive; therefore, its long-term and extensive application is limited.
Weiwei Huang +13 more
semanticscholar +1 more source