Results 131 to 140 of about 64,954 (254)

Development and Validation of an ELISA to Detect Antibody to Onchocerca volvulus Infection Using Mammalian Expressed Recombinant Ov16. [PDF]

Am J Trop Med Hyg
Ossai S, Wang Y, Elder ES, Wickens K, Won KY, Secor WE, Handali S.   +6 more
europepmc   +1 more source

Nemolizumab for Pruritus Control in Cutaneous T‐Cell Lymphoma: A Case Series

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Yenny Angela, Ralf Gutzmer, Rudolf Stadler   +2 more
wiley   +1 more source

Superior Clinical and Economic Value of IL‐23 Inhibitors Versus Adalimumab Biosimilars in Plaque Psoriasis

International Journal of Dermatology, EarlyView.
A bicentric retrospective real‐world study (N = 616) comparing IL‐23 inhibitors (guselkumab, risankizumab, tildrakizumab) with adalimumab biosimilars in moderate‐to‐severe plaque psoriasis. It presents PASI90 response at Weeks 16 and 52, NNT, and cost‐effectiveness (incremental cost per responder, CE plane, CEAC/CEAF).
Gennaro Marco Falco, Elena Ippoliti, Niccolò Gori, Giacomo Caldarola, Clara De Simone, Nicoletta Di Giorgi, Paulo Gabriel Longo, Marco Galluzzo, Luca Bianchi, Lorenzo Marcelli, Marina Talamonti, Maria Vittoria Cannizzaro, Lucia Di Nardo, Ketty Peris   +13 more
wiley   +1 more source

Engineering strategies and binding mechanisms of therapeutic anti-PD-1 antibodies approved by regulatory agencies globally. [PDF]

Front Immunol
Almagro JC, Gómez-Castellano K, Licona-Limón I, Carballo Uicab GJ, Ramírez-Villedas FD, Montes-Luna A, González-González E, Godínez-Palma S, Barrera Saldaña HA, Pérez-Tapia SM.   +9 more
europepmc   +1 more source

Searching for LADA in patients with Hashimoto's thyroiditis: A tool for the prevention of LADA

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Autoimmune thyroid diseases (AITD), such as Hashimoto's thyroiditis (HT), frequently co‐occur with autoimmune diabetes, including latent autoimmune diabetes in adults (LADA). While guidelines recommend thyroid autoantibody screening in patients with autoimmune diabetes, the reverse approach—screening for diabetes‐related autoantibodies in AITD
Kozlowska Alicja Anna, Messina Maria Vittoria, Pozzilli Paolo   +2 more
wiley   +1 more source

Transfer of trastuzumab and pertuzumab into human breast milk: a case report. [PDF]

Cancer Chemother Pharmacol
Buitelaar PLM, Pluim D, Hanssens S, Kerbage Y, Rosing H, Huitema ADR, Amant FC.   +6 more
europepmc   +1 more source

Long‐term efficacy of biologics in moderate‐to‐severe hidradenitis suppurativa: A systematic review and MAIC

Journal of the European Academy of Dermatology and Venereology, EarlyView.
A matching‐adjusted indirect treatment comparison (MAIC) was conducted, comparing approved biologics for long‐term (48–52 weeks) treatment of moderate‐to‐severe hidradenitis suppurativa (HS). Using weighted patient‐level trial data allowed re‐estimation of relative bimekizumab efficacy compared with aggregate secukinumab and adalimumab trial data ...
Thrasyvoulos Tzellos, Vincent Piguet, Michael Frank Mørup, Leah Davis, Vanessa Taieb, Sandeep Kiri, Victoria Shodimu, Abby Paine, Brian Kirby, Haley B. Naik   +9 more
wiley   +1 more source

A Paradigm Shift in Snakebite Envenoming Therapy: From Conventional Antivenoms to Rationally Designed, Broadly Neutralizing Combination Therapies. [PDF]

ACS Pharmacol Transl Sci
Shi N, Wang J, Xu C, Jiang X, Ren C, Gao X, Luo L.   +6 more
europepmc   +1 more source

Litifilimab efficacy on skin outcomes in cutaneous lupus erythematosus in the Phase 2 LILAC study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Our findings show that greater proportions of litifilimab‐treated participants than placebo experienced 20%, 50%, 70% or 90% improvements in CLASI‐A score from baseline and CLASI‐A scores of 0–1 or 0–3. Similar results were observed using physician global assessments, supporting the Phase 2 LILAC study primary analysis in CLE.
Victoria P. Werth, Joseph F. Merola, Richard Furie, Kenneth Kalunian, Ronald F. van Vollenhoven, Juanita Romero‐Diaz, Qianyun Li, Weihong Yang, Catherine Barbey   +8 more
wiley   +1 more source

Development and Validation of Cell-Based Bioassay for the Detection of Neutralizing Antibodies to Ocrelizumab in Human Serum Using Antibody-Dependent Cell-Mediated Cytotoxicity Test in a Reporter Cell Line Expressing FcγRIIIa. [PDF]

Antibodies (Basel)
Strizhakova O, Poroshin G, Pershin A, Bakhareva Y, Shevchenko I, Lyagoskin I, Shukurov R, Khamitov R.   +7 more
europepmc   +1 more source