Forty different monoclonal antibodies were produced from hybridomas that were raised against human Lp[a]. Of these, 14 strongly cross-reacted with plasminogen on ELISA screening assays while 16 clearly did not and 10 were only marginally cross-reactive ...
MA Lafferty, AM Salamon, DC Usher
doaj
ABodyBuilder3: Improved and scalable antibody structure predictions [PDF]
Accurate prediction of antibody structure is a central task in the design and development of monoclonal antibodies, notably to understand both their developability and their binding properties. In this article, we introduce ABodyBuilder3, an improved and scalable antibody structure prediction model based on ImmuneBuilder.
arxiv
Uncertainty Quantification of Antibody Measurements: Physical Principles and Implications for Standardization [PDF]
Harmonizing serology measurements is critical for identifying reference materials that permit standardization and comparison of results across different diagnostic platforms. However, the theoretical foundations of such tasks have yet to be fully explored in the context of antibody thermodynamics and uncertainty quantification (UQ). This has restricted
arxiv
We established five monoclonal antibodies that reacted with human LCAT and recognized different epitopes on LCAT. These are mouse anti-human LCAT monoclonal antibodies designated 36487, 36454, 36442, 36405, and 36486, which react with the peptides ...
Kiichiro Kobori+5 more
doaj
Electrostatics and viscosity are strongly linked in concentrated antibody solutions [PDF]
Monoclonal antibodies are among the most promising therapeutic agents in modern medicine, yet their formulation into high-concentration solutions for subcutaneous self-administration poses a major challenge. A key obstacle is the marked increase in viscosity often observed under these conditions.
arxiv
Erratum: Anti-Amyloid Imaging Abnormality in the Era of Anti-Amyloid Beta Monoclonal Antibodies: Recent Updates for the Radiologist. [PDF]
Jeong SY+6 more
europepmc +1 more source
Enhancing ovarian cancer treatment by synergistically targeting HER2 and PD-L1. [PDF]
Zhang S, Pan Q, Wang K.
europepmc +1 more source
Dual biological treatments in immune-mediated disorders: a single center experience. [PDF]
Shamriz O+8 more
europepmc +1 more source
Photocatalyzed elaboration of antibody-based bioconjugates. [PDF]
Le Stum M, Romero E, Molander GA.
europepmc +1 more source
Development of a Monoclonal Antibody Against Duck IFN-γ Protein and the Application for Intracellular Cytokine Staining. [PDF]
Chen Y+6 more
europepmc +1 more source