Results 71 to 80 of about 627,035 (125)

Immunochemistry of human Lp[a]: characterization of monoclonal antibodies that cross-react strongly with plasminogen.

open access: yesJournal of Lipid Research, 1991
Forty different monoclonal antibodies were produced from hybridomas that were raised against human Lp[a]. Of these, 14 strongly cross-reacted with plasminogen on ELISA screening assays while 16 clearly did not and 10 were only marginally cross-reactive ...
MA Lafferty, AM Salamon, DC Usher
doaj  

ABodyBuilder3: Improved and scalable antibody structure predictions [PDF]

open access: yesarXiv
Accurate prediction of antibody structure is a central task in the design and development of monoclonal antibodies, notably to understand both their developability and their binding properties. In this article, we introduce ABodyBuilder3, an improved and scalable antibody structure prediction model based on ImmuneBuilder.
arxiv  

Uncertainty Quantification of Antibody Measurements: Physical Principles and Implications for Standardization [PDF]

open access: yesarXiv
Harmonizing serology measurements is critical for identifying reference materials that permit standardization and comparison of results across different diagnostic platforms. However, the theoretical foundations of such tasks have yet to be fully explored in the context of antibody thermodynamics and uncertainty quantification (UQ). This has restricted
arxiv  

A new enzyme-linked immunosorbent assay with two monoclonal antibodies to specific epitopes measures human lecithin-cholesterol acyltransferase

open access: yesJournal of Lipid Research, 2002
We established five monoclonal antibodies that reacted with human LCAT and recognized different epitopes on LCAT. These are mouse anti-human LCAT monoclonal antibodies designated 36487, 36454, 36442, 36405, and 36486, which react with the peptides ...
Kiichiro Kobori   +5 more
doaj  

Electrostatics and viscosity are strongly linked in concentrated antibody solutions [PDF]

open access: yesarXiv
Monoclonal antibodies are among the most promising therapeutic agents in modern medicine, yet their formulation into high-concentration solutions for subcutaneous self-administration poses a major challenge. A key obstacle is the marked increase in viscosity often observed under these conditions.
arxiv  

Dual biological treatments in immune-mediated disorders: a single center experience. [PDF]

open access: yesBMC Immunol
Shamriz O   +8 more
europepmc   +1 more source

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