Results 241 to 250 of about 1,727,618 (310)

Divergent antibody recognition profiles are generated by protective mRNA vaccines against Marburg and Ravn viruses. [PDF]

Nat Commun
Meyer M, Gunn BM, Pietzsch C, Subramani C, Kedarinath K, Villarreal PP, Hyde MA, Saphire EO, Crowe JE, Alter G, Himansu S, Carfi A, Bukreyev A.   +12 more
europepmc   +1 more source

Pectin Metabolism Influences Phloem Architecture and Flowering Time in Arabidopsis Thaliana

Advanced Science, EarlyView.
Cell wall remodeling mediated by changes in pectic homogalacturonan, including its methyl‐esterification status and degradation, shapes wall architecture. This study finds that pectin metabolism dynamically modulates wall properties and triggers auxin responses, which influence phloem morphogenesis and function, mediating the long‐distance transport of
Qing Zhang, Juan Du, Shuang Hao, Zhengmei Leng, Weiguo Liu, Chengjian Zhao, Yue Yu, Longquan Chen, Charles T. Anderson, Chaowen Xiao   +9 more
wiley   +1 more source

Env-pseudoviruses based on the HIV-1 genetic variant circulating in Siberia. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Rudometova NB, Fando AA, Shcherbakov DN, Zaitsev BN, Rudometov AP, Karpenko LI.   +5 more
europepmc   +1 more source

Macrophage‐Mediated Transport of Insoluble Indirubin Induces Hepatic Injury During Intestinal Inflammation

Advanced Science, EarlyView.
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu, Jingchun Shi, Heung‐Lam Mok, Cheng Lyu, Junbang Chen, Chunhua Huang, Hongyan Qin, Chengyuan Lin, Hor‐Yue Tan, Zhaoxiang Bian   +9 more
wiley   +1 more source

Passive immunotherapy for adults hospitalized with COVID-19: An individual participant data meta-analysis of six randomized controlled trials. [PDF]

PLoS Med
Knowlton KU, Siegel LK, Barkauskas CE, Bhagani S, Dharan NJ, Gardner EM, Gottlieb RL, Helleberg M, Highbarger HC, Holland TL, Heerfordt CK, Lazarte S, Leither LM, Lutaakome J, Ardelt M, Mylonakis E, Ong SWX, Overcash JS, Taha H, Tien PC, Trautner BW, Vallee D, Weintrob AC, Touloumi G, Babiker AG, STRIVE ACTIV-3/TICO Study Group.   +25 more
europepmc   +1 more source

Characterization of B Cell Responses in Rainbow Trout (Oncorhynchus Mykiss) Affected by Red Mark Syndrome

Advanced Science, EarlyView.
This study extensively characterizes the B cell response of rainbow trout (Oncorhynchus mykiss) in response to red mark syndrome (RMS). This disease, suspected to be caused by a Midichloria‐like organism (MLO), induces skin lesions in the infected animals, characterized by a massive influx of IgM+ B cells.
J Germán Herranz‐Jusdado, Samuel Vicente‐Gil, Esther Morel, Pablo Jiménez‐Barrios, Rocío Simón, Pedro Perdiguero, Diana Martín, Marta Vargas‐Ramírez, Niels Lorenzen, Jacob Günther Schmidt, Carolina Tafalla   +10 more
wiley   +1 more source

Serological evidence of bluetongue virus serotypes circulating in Pakistan.

Intervirology
Ishaq M, Jamal SM, Ali S, Teodori L, Leone A, Bonfini B, Spedicato M, Savini G.   +7 more
europepmc   +1 more source

Neutralizing antibody levels as a key factor in determining the immunogenic efficacy of the novel PEDV alpha coronavirus vaccine. [PDF]

Vet Q
Hu G, Luo X, Liao J, Zou C, Huang Y, Geng R, Zhao Z, Shen H, Cao Y, Peng O, Zhang H.   +10 more
europepmc   +1 more source

The Role of HINT3 in Myocardial Ischemia‐Reperfusion Injury in Male Mice: Mechanisms Involving SDHA and its Acetylation

Advanced Science, EarlyView.
HINT3 expression declines after myocardial ischemia‐reperfusion injury. In male mice, loss of HINT3 worsens cardiac injury and mitochondrial dysfunction, while its overexpression is protective. HINT3 binds the mitochondrial enzyme succinate dehydrogenase (SDHA) and prevents its deacetylation by histone deacetylase 1 (HDAC1), reducing succinate ...
Jiabin Yu, Qi Yao, Tongtong Hu, Yadan Zhang, Ying Liu, Yang Xiao, Qingqing Wu, Qizhu Tang   +7 more
wiley   +1 more source