Results 41 to 50 of about 1,830,458 (346)

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding [PDF]

open access: yes, 2011
Passive transfer of broadly neutralizing HIV antibodies can prevent infection, which suggests that vaccines that elicit such antibodies would be protective.
Abadir, Alexander   +21 more
core   +2 more sources

Immune characterization of a Colombian family cluster with SARS-CoV-2 infection

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2021
Introduction: Immunological markers have been described during COVID-19 and persist after recovery. These immune markers are associated with clinical features among SARSCoV-2 infected individuals.
Wbeimar Aguilar-Jiménez   +15 more
doaj   +1 more source

SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral Spike vaccines

open access: yesbioRxiv, 2021
The SARS-CoV-2 Spike glycoprotein mediates virus entry and is a major target for neutralizing antibodies. All current vaccines are based on the ancestral Spike with the goal of generating a protective neutralizing antibody response.
Xiaoying Shen   +17 more
semanticscholar   +1 more source

COVID-19 neutralizing antibodies predict disease severity and survival

open access: yesmedRxiv, 2020
COVID-19 exhibits variable symptom severity ranging from asymptomatic to life-threatening, yet the relationship between severity and the humoral immune response is poorly understood.
W. García-Beltrán   +19 more
semanticscholar   +2 more sources

A sensitive and reproducible cell-based assay via secNanoLuc to detect neutralizing antibody against adeno-associated virus vector capsid

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
Most gene therapy clinical trials that systemically administered adeno-associated virus (AAV) vector enrolled only patients without anti-AAV-neutralizing antibodies.
Nemekhbayar Baatartsogt   +6 more
doaj  

ZIKV Envelope Domain-Specific Antibodies: Production, Purification and Characterization

open access: yesViruses, 2019
Infection with Zika virus (ZIKV) came first to public attention after it was found to be associated with congenital microcephaly during the outbreak in Brazil (2015–2016). Diagnosis of ZIKV suffers from extensive cross-reactivity with other Flaviviruses,
Sami Akhras   +4 more
doaj   +1 more source

bNAber: database of broadly neutralizing HIV antibodies. [PDF]

open access: yes, 2013
The discovery of broadly neutralizing antibodies (bNAbs) has provided an enormous impetus to the HIV vaccine research and to entire immunology. The bNAber database at http://bNAber.org provides open, user-friendly access to detailed data on the rapidly ...
Burton, Dennis R   +8 more
core   +4 more sources

Review of therapeutic mechanisms and applications based on SARS-CoV-2 neutralizing antibodies

open access: yesFrontiers in Microbiology, 2023
COVID-19 pandemic is a global public health emergency. Despite extensive research, there are still few effective treatment options available today. Neutralizing-antibody-based treatments offer a broad range of applications, including the prevention and ...
Mingtao Liu   +11 more
doaj   +1 more source

Pan-Sarbecovirus Neutralizing Antibodies in BNT162b2-Immunized SARS-CoV-1 Survivors

open access: yesNew England Journal of Medicine, 2021
Summary Emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern pose a challenge to the effectiveness of current vaccines.
C. Tan   +10 more
semanticscholar   +1 more source

Antibody and Virus: Binding and Neutralization

open access: yesVirology, 2000
During infection with an enveloped virus, antibodiesare elicited to envelope proteins. Some of these antibod-ies bind to envelope spikes on the virion, some bind tononvirion forms of the envelope (“viral debris”), and somebind to both. The relative amounts of different antibodytypes elicited varies from virus to virus.
Paul W. H. I. Parren   +2 more
openaire   +2 more sources

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