Results 41 to 50 of about 294,536 (285)

Neutralizing Monoclonal Antibodies Reduce Human Cytomegalovirus Infection and Spread in Developing Placentas. [PDF]

, 2019
Congenital human cytomegalovirus (HCMV) infection is a leading cause of birth defects worldwide, yet the most effective strategies for preventing virus transmission during pregnancy are unknown.
An, Zhiqiang, Fang-Hoover, June, Freed, Daniel C, Fu, Tong-Ming, Li, Fengsheng, Pereira, Lenore, Petitt, Matthew, Tabata, Takako, Wang, Dai   +8 more
core   +1 more source

Continuous Delivery of Neutralizing Antibodies Elevate CCL2 Levels in Mice Bearing MCF10CA1d Breast Tumor Xenografts

Translational Oncology, 2017
Chemokines are small soluble molecules that play critical roles in wound healing, infection, and cancer progression. In particular, overexpression of the C-C motif chemokine ligand 2 (CCL2) in multiple cancer types correlates with poor patient prognosis.
Min Yao, Curtis Smart, Qingting Hu, Nikki Cheng   +3 more
doaj   +1 more source

Neutralizing antiviral antibody responses

, 2001
Neutralizing antibodies are evolutionarily important effectors of immunity against viruses. Their evaluation has revealed a number of basic insights into specificity, rules of reactivity (tolerance), and memory—namely, (1) Specificity of neutralizing antibodies is defined by their capacity to distinguish between virus serotypes; (2) B cell reactivity ...
Zinkernagel, R, LaMarre, A, Ciurea, A, Hunziker, L, Ochsenbein, A, McCoy, K, Fehr, T, Bachmann, M, Kalinke, U, Hengartner, H   +9 more
openaire   +2 more sources

Neutralizing antibodies against coronaviruses [PDF]

Microscopy and Microanalysis, 2021
Neutralizing monoclonal antibodies against SARS-CoV-2 are being used as therapeutics against COVID-19. The Bjorkman laboratory is investigating the mechanisms of virus neutralization by human antibodies that bind the SARSCoV- 2 spike protein. Using structural techniques, including single-particle cryoelectron microscopy and X-ray crystallography, the ...
openaire   +2 more sources

BNT162b2 Vaccination after SARS-CoV-2 Infection Changes the Dynamics of Total and Neutralizing Antibodies against SARS-CoV-2: A 6-Month Prospective Cohort Study

Vaccines, 2023
This study aimed to analyze the dynamics, duration, and production of total and neutralizing antibodies induced by the BNT162b2 vaccine and the possible effect of gender and prior SARS-CoV-2 infection on the generation of these antibodies.
Jorge Hernández-Bello, José Julio Sierra-García-de-Quevedo, José Javier Morales-Núñez, Guillermo Santoscoy-Ascencio, Saúl Alberto Díaz-Pérez, Jesús Alberto Gutiérrez-Brito, José Francisco Muñoz-Valle   +6 more
doaj   +1 more source

Immunogens and Antigen Processing: Report from a Global HIV Vaccine Enterprise Working Group [PDF]

, 2010
The Global HIV Vaccine Enterprise convened a meeting of a Working Group in July 2009 to discuss recent progress in rational design of the components of an HIV vaccine, such as inserts, vectors and adjuvants,and in understanding antigen processing and ...
John Mascola, Ralph Steinman, Richter C. King, the Working Group convened by the Global HIV Vaccine Enterprise   +3 more
core   +3 more sources

Evidence for West Nile Virus and Usutu Virus Infections in Wild and Resident Birds in Germany, 2017 and 2018 [PDF]

, 2019
Wild birds play an important role as reservoir hosts and vectors for zoonotic arboviruses and foster their spread. Usutu virus (USUV) has been circulating endemically in Germany since 2011, while West Nile virus (WNV) was first diagnosed in several bird ...
Eiden, Martin, Fast, Christine, Fischer, Dominik, Groschup, Martin H., Keller, Markus, Korbel, Rüdiger, Lierz, Michael, Lühken, Renke, Michel, Friederike, Müller, Kerstin, Reuschel, Maximilian, Rinder, Monika, Schmidt, Volker, Schmoock, Martina, Schwehn, Rebekka, Sieg, Michael, Urbaniak, Sylvia, Vahlenkamp, Thomas W., Wysocki, Patrick, Ziegler, Ute   +19 more
core   +2 more sources

Broad and potent cross clade neutralizing antibodies with multiple specificities in the plasma of HIV-1 subtype C infected individuals. [PDF]

, 2017
Broadly Cross clade Neutralizing (BCN) antibodies are recognized as potential therapeutic tools and leads for the design of a vaccine that can protect human beings against various clades of Human Immunodeficiency Virus (HIV).
Ashokkumar, Manickam, Babu, Hemalatha, Buddolla, Viswanath, Chandrasekaran, Padmapriyadarsini, Cheedarla, Narayanaiah, Hanna, Luke Elizabeth, Kailasam, Nandagopal, Precilla, K Lucia, Ramanathan, VD, Sundaramurthi, Jagadish Chandrabose, Swaminathan, Soumya, Vaniambadi, S Kalyanaraman, Vijayan, KK Vidya   +12 more
core   +3 more sources

Defining criteria for broadly neutralizing HIV antibodies

Frontiers in Immunology
Over the course of a few years, a small percentage of individuals with HIV-1 develop broadly neutralizing antibodies (bnAbs) capable of neutralizing diverse viruses.
Elizabeth-Sharon David-Fung, Katherine A. Belobrajdic, Jennifer P. Macke, Corey R. Quackenbush, Kumkum Ganguly, Jennifer L. Mamrosh   +5 more
doaj   +1 more source

Analysis of dengue specific memory B cells, neutralizing antibodies and binding antibodies in healthy adults from India

International Journal of Infectious Diseases, 2019
Background: The Indian population is facing highest dengue burden worldwide supporting an urgent need for vaccines. For vaccine introduction, evaluation and interpretation it is important to gain a critical understanding of immune memory induced by ...
Sivaram Gunisetty, Kaustuv Nayak, Ramesh Chandra Rai, Yadya Chawla, Elluri Seetharami Reddy, Charu Aggarwal, Deepti Maheshwari, Harekrushna Panda, Nasim Akhtar Ansari, Prabhat Singh, Manpreet Kaur, Kritika Dixit, Pragati Sharma, Priya Bhatnagar, Lalita Priyamvada, Siddhartha Kumar Bhaumik, Syed Fazil Ahamed, Rosario Vivek, Pratima Ray, Anita Shet, Poonam Coshic, Rakesh Lodha, Sushil Kumar Kabra, Dil Afroze, Adfar Yousuf, Rafi Ahmed, Kaja Murali-Krishna, Anmol Chandele   +27 more
doaj   +1 more source