Results 51 to 60 of about 1,727,618 (310)
PLoS ONE, 2023 Despite development of effective SARS-CoV-2 vaccines, a sub-group of vaccine non-responders depends on therapeutic antibodies or small-molecule drugs in cases of severe disease.
Stine Sofie Frank Lende +17 more
doaj +1 more source
SARS-CoV-2 spike protein: a key target for eliciting persistent neutralizing antibodies
Signal Transduction and Targeted Therapy, 2021 A recent paper published in Science describes the detection of IgG antibody responses in individuals infected by severe acute respiratory syndrome coronavirus (SARS-CoV-2). The authors also examined the duration of antibody production and the correlation
Yang Yang, L. Du
semanticscholar +1 more source
Antibody neutralization of HIV-1
Immunology Today, 1996 Neutralizing antibodies are a major component of host defense against viruses, and appear to be particularly important in limiting the spread of cell-free virus. Results from vaccine trials in animal models suggest that these antibodies may contribute to protection against human immunodeficiency virus (HIV) infection.
Poignard, P, Klasse, P, Sattentau, Q
openaire +2 more sources
Feline Immunodeficiency Virus (FIV) Neutralization: A Review
Viruses, 2011 One of the major obstacles that must be overcome in the design of effective lentiviral vaccines is the ability of lentiviruses to evolve in order to escape from neutralizing antibodies.
Margaret J. Hosie +3 more
doaj +1 more source
Broadly neutralizing antibodies target a haemagglutinin anchor epitope
Nature, 2021 Broadly neutralizing antibodies that target epitopes of haemagglutinin on the influenza virus have the potential to provide near universal protection against influenza virus infection1.
Jenna J. Guthmiller +32 more
semanticscholar +1 more source
RSV Neutralizing Antibodies in Dried Blood
The Journal of Infectious Diseases, 2023 Abstract Background The key correlate of protection of respiratory syncytial virus (RSV) vaccines and monoclonal antibodies (mAbs) is virus neutralization, measured via sera obtained through venipuncture.
Jonne Terstappen +7 more
openaire +3 more sources
Neutralizing Antibodies Responses to SARS-CoV-2 in COVID-19 Inpatients and Convalescent Patients
medRxiv, 2020 Background. COVID-19 is a pandemic with no specific antiviral treatments or vaccines. The urgent needs for exploring the neutralizing antibodies from patients with different clinical characteristics are emerging. Methods.
Xiaoli Wang +8 more
semanticscholar +1 more source
SARS-CoV-2 Neutralizing Antibodies for COVID-19 Prevention and Treatment.
Annual Review of Medicine, 2021 Prophylactic and therapeutic drugs are urgently needed to combat coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Dapeng Li +4 more
semanticscholar +1 more source
Signatures in SARS-CoV-2 spike protein conferring escape to neutralizing antibodies
PLoS Pathogens, 2021 Understanding SARS-CoV-2 evolution and host immunity is critical to control COVID-19 pandemics. At the core is an arms-race between SARS-CoV-2 antibody and angiotensin-converting enzyme 2 (ACE2) recognition, a function of the viral protein spike ...
Marta Alenquer +14 more
semanticscholar +1 more source
Neutralizing antiviral antibody responses
, 2001 Neutralizing antibodies are evolutionarily important effectors of immunity against viruses. Their evaluation has revealed a number of basic insights into specificity, rules of reactivity (tolerance), and memory—namely, (1) Specificity of neutralizing antibodies is defined by their capacity to distinguish between virus serotypes; (2) B cell reactivity ...
Zinkernagel, R +9 more
openaire +3 more sources