Monoclonal Antibodies for Protozoan Infections: A Future Reality or a Utopic Idea? [PDF]
Following the SARS-CoV-2 pandemic, several clinical trials have been approved for the investigation of the possible use of mAbs, supporting the potential of this technology as a therapeutic approach for infectious diseases. The first monoclonal antibody (
Silvia Stefania Longoni +4 more
doaj +3 more sources
Seroprevalence rates of antibodies againstLeishmania infantum and other protozoan and rickettsial parasites in dogs [PDF]
Canine visceral leishmaniasis (CVL) is caused by the protozoan Leishmania infantum, which infects dogs and humans in many regions of Brazil. The present study involved an indirect fluorescent antibody test (IFAT) to analyze L.
Silvana de Cássia Paulan +7 more
doaj +4 more sources
Effect of biannual azithromycin distribution on antibody responses to malaria, bacterial, and protozoan pathogens in Niger [PDF]
Abstract The MORDOR trial in Niger, Malawi, and Tanzania found that biannual mass distribution of azithromycin to children younger than 5 years led to a 13.5% reduction in all-cause mortality (NCT02048007). To help elucidate the mechanism for mortality reduction, we report IgG responses to 11 malaria, bacterial ...
Ahmed M. Arzika +15 more
openaire +5 more sources
Specificity of SARS-CoV-2 antibody-detection assays against S and N protein among pre-COVID-19 sera from patients with protozoan and helminth parasitic infections [PDF]
ABSTRACTBackgroundWe aimed to assess the specificity of SARS-CoV-2 antibody detection assays among people with known tissue-borne parasitic infections.MethodsWe tested three SARS-CoV-2 antibody-detection assays (cPass SARS-CoV-2 Neutralization Antibody Detection Kit, Abbott SARS-CoV-2 IgG assay, and STANDARD Q COVID-19 IgM/IgG Combo Rapid Test) among ...
Cedric P. Yansouni +12 more
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Use of Phage Antibodies to Distinguish Closely Related Species of Protozoan Parasites [PDF]
Acanthamoeba are typically identified in the laboratory using culture and microscopic observation. In this paper we describe the isolation and specificity of antibody fragments that can be used for the identification of Acanthamoeba. A phage library expressing a large repertoire (approx.
Timothy Paget +4 more
openaire +2 more sources
Adaptation of CUT&RUN for use in African trypanosomes.
This Cleavage Under Targets and Release Using Nuclease (CUT&RUN) protocol produces genomic occupancy data for a protein of interest in the protozoan parasite Trypanosoma brucei. The data produced is analyzed in a similar way as that produced by ChIP-seq.
Geneva Miller +4 more
doaj +1 more source
IgG Antibody responses in mice coinfected with Toxocara canis and other helminths or protozoan parasites [PDF]
The immune response expressed by IgG antibodies in BALB/c mice experimentally infected with Toxocara canis, was studied with the aim of verifying the possible in vivo cross-reactivity between antigens of T. canis and other parasites (Ascaris suum, Taenia crassiceps, Schistosoma mansoni, Strongyloides venezuelensis and Toxoplasma gondii).
Lescano, Susana A. Zevallos +3 more
openaire +5 more sources
Toxoplasma gondii in cattle in Brazil: a review
Toxoplasma gondii is an apicomplexan protozoan that is frequently found in both humans and animals worldwide. The aim of this review was to list important aspects of Toxoplasma gondii infection in cattle in Brazil.
Daniella Ferreira Cordeiro Gomes +7 more
doaj +1 more source
Effect of biannual azithromycin distribution on antibody responses to malaria, bacterial, and protozoan pathogens among children: A cluster-randomized, placebo-controlled trial in Niger [PDF]
AbstractBackgroundThe Macrolides Oraux pour Réduire les Décès avec un Oeil sur la Résistance (MORDOR) trial in Niger, Malawi, and Tanzania found that biannual mass distribution of azithromycin to children younger than 5 years led to a 13.5% reduction in all-cause mortality.
Ahmed M. Arzika +14 more
openaire +1 more source
Background Limited information about Toxoplasma gondii infection in pet cats and their owners is available in China. Methods In this study, blood samples were randomly collected from 306 pet cats and 397 corresponding pet owners in Jilin province ...
Xin-Tong Li +3 more
doaj +1 more source

