Results 11 to 20 of about 543,537 (197)

Monoclonal Antibodies for Protozoan Infections: A Future Reality or a Utopic Idea? [PDF]

Frontiers in Medicine, 2021
Following the SARS-CoV-2 pandemic, several clinical trials have been approved for the investigation of the possible use of mAbs, supporting the potential of this technology as a therapeutic approach for infectious diseases. The first monoclonal antibody (
Silvia Stefania Longoni, Natalia Tiberti, Zeno Bisoffi, Zeno Bisoffi, Chiara Piubelli   +4 more
doaj   +3 more sources

Seroprevalence rates of antibodies againstLeishmania infantum and other protozoan and rickettsial parasites in dogs [PDF]

Revista Brasileira de Parasitologia Veterinária, 2013
Canine visceral leishmaniasis (CVL) is caused by the protozoan Leishmania infantum, which infects dogs and humans in many regions of Brazil. The present study involved an indirect fluorescent antibody test (IFAT) to analyze L.
Silvana de Cássia Paulan, Aline Gouveia de Souza Lins, Michely da Silva Tenório, Diogo Tiago da Silva, Hilda Fátima de Jesus Pena, Rosangela Zacarias Machado, Solange Maria Gennari, Wilma Aparecida Starke Buzetti   +7 more
doaj   +4 more sources

Occurrence and Risk Factors of Toxoplasma gondii Infection in Tigers (Panthera tigris) in Thailand: Influence of Age and Sex [PDF]

Veterinary Medicine and Science
Background Toxoplasma gondii is a zoonotic protozoan parasite of significant concern in both public and animal health. Objectives This study investigated the occurrence of T.
Phirom Prompiram, Chalisa Mongkolphan, Aeknarin Saechin, Siriporn Tangsudjai, Kanaporn Poltep   +4 more
doaj   +2 more sources

B-Cell Response during Protozoan Parasite Infections [PDF]

Journal of Parasitology Research, 2012
In this review, we discuss how protozoan parasites alter immature and mature B cell compartment. B1 and marginal zone (MZ) B cells, considered innate like B cells, are activated during protozoan parasite infections, and they generate short lived plasma ...
María C. Amezcua Vesely, Daniela A. Bermejo, Carolina L. Montes, Eva V. Acosta-Rodríguez, Adriana Gruppi   +4 more
doaj   +2 more sources

Serosurvey of Toxoplasmosis Among Drug Users in Fars Province, Southern Iran: A Cross-Sectional Study. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Toxoplasma gondii is a widespread zoonotic protozoan that poses significant health risks, particularly to immunocompromised individuals. Although generally asymptomatic, toxoplasmosis can lead to severe neurological complications and behavioral disorders.
Cheraghi MR, Zarrabi M, Shahriarirad S, Rohampour S, Shayan G, Omidian M, Rezaee E, Sarvari J, Gheshlaghi A, Asgari Q, Sarkari B.   +10 more
europepmc   +2 more sources

Effect of biannual azithromycin distribution on antibody responses to malaria, bacterial, and protozoan pathogens in Niger [PDF]

Nature Communications, 2022
Abstract The MORDOR trial in Niger, Malawi, and Tanzania found that biannual mass distribution of azithromycin to children younger than 5 years led to a 13.5% reduction in all-cause mortality (NCT02048007). To help elucidate the mechanism for mortality reduction, we report IgG responses to 11 malaria, bacterial ...
Ahmed M. Arzika, Ramatou Maliki, E. Brook Goodhew, Eric Rogier, Jeffrey W. Priest, Elodie Lebas, Kieran S. O’Brien, Victoria Le, Catherine E. Oldenburg, Thuy Doan, Travis C. Porco, Jeremy D. Keenan, Thomas M. Lietman, Diana L. Martin, Benjamin F. Arnold, MORDOR-Niger Study Group   +15 more
openaire   +5 more sources

Development of antibodies for life-detection experiment in extreme environments; implications for astrobiology [PDF]

, 2010
The Life Marker Chip (LMC) instrument is an antibody assay-based system which will attempt to detect molecular signatures of Life in the Martian subsurface as part of the payload on board the European Space Agency (ESA) ExoMars mission rover, currently
Derveni, Maria Elisavet
core   +7 more sources

Use of Phage Antibodies to Distinguish Closely Related Species of Protozoan Parasites [PDF]

Disease Markers, 2000
Acanthamoeba are typically identified in the laboratory using culture and microscopic observation. In this paper we describe the isolation and specificity of antibody fragments that can be used for the identification of Acanthamoeba. A phage library expressing a large repertoire (approx.
Timothy Paget, Naveed Khan, Graham Temple, Victoria Hough, John Greenman   +4 more
openaire   +2 more sources

Specificity of SARS-CoV-2 antibody-detection assays against S and N protein among pre-COVID-19 sera from patients with protozoan and helminth parasitic infections [PDF]

Journal of Clinical Microbiology, 2021
ABSTRACT Background We aimed to assess the specificity of SARS-CoV-2 antibody detection assays among people with known tissue-borne parasitic infections. Methods We tested three SARS-CoV-2 antibody-detection assays (cPass SARS-CoV ...
Cedric P. Yansouni, Jesse Papenburg, Matthew P. Cheng, Rachel Corsini, Chelsea Caya, Fabio Vasquez Camargo, Luke B. Harrison, Gerasimos Zaharatos, Philippe Büscher, Babacar Faye, Magatte Ndiaye, Greg Matlashewski, Momar Ndao   +12 more
openaire   +2 more sources

Adaptation of CUT&RUN for use in African trypanosomes.

PLoS ONE, 2023
This Cleavage Under Targets and Release Using Nuclease (CUT&RUN) protocol produces genomic occupancy data for a protein of interest in the protozoan parasite Trypanosoma brucei. The data produced is analyzed in a similar way as that produced by ChIP-seq.
Geneva Miller, Lindsey M Rollosson, Carrie Saada, Serenity J Wade, Danae Schulz   +4 more
doaj   +1 more source