Malaria vaccine protection against intradermal or venous parasites: a randomized phase 2b human challenge trial. [PDF]
Kapulu MC +37 more
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Development of a camelid single-domain antibody-based antigen detection assay for the pan-specific diagnosis of active human and animal <i>Trypanosoma brucei</i> infections. [PDF]
Li Z +8 more
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Seroprevalence and genetic characterization of Toxoplasma gondii in hunted wild boars (Sus scrofa) from Croatia. [PDF]
Grbavac L +10 more
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Identification of highly cross-reactive immunogens in Eimeria tenella sporozoites. [PDF]
Chen W +6 more
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Cure of experimental <i>Trypanosoma vivax</i> infection with a single dose of an unmodified antibody-based drug targeting the invariant flagellum cell surface protein IFX. [PDF]
Autheman D +6 more
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Antibodies to protozoan variable surface antigens induce antigenic variation
2022AbstractThe genomes of most protozoa encode families of variant surface antigens, whose mutually exclusive changes in expression allow parasitic microorganisms to evade the host immune response1,2. It is widely assumed that antigenic variation in protozoan parasites is accomplished by the spontaneous appearance within the population of cells expressing
Albano H. Tenaglia +17 more
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ANTIBODY‐INDUCED MOVEMENT OF PROTOZOAN SURFACE MEMBRANE ANTIGENS*
Annals of the New York Academy of Sciences, 1975Direct and indirect immunofluorescence techniques were used to study the effects of host antibodies on surface membrane antigens of viable Leishmania parasites in vitro. Antisera to L. enriettii and L. tropica caused surface membrane antigens of these parasites to aggregate, move toward the poles of the parasite, and to eventually disappear.
J J, Doyle +3 more
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Use of Hybridoma Antibodies and Recombinant DNA Technology in Protozoan Vaccine Development
Avian Diseases, 1986The use of hybridoma antibodies developed against the sporozoite stage of avian coccidia, coupled with genetic-engineering techniques, has made it possible to begin bird-immunization studies utilizing an Escherichia coli-elicited coccidial protein. The coccidia are currently controlled in the poultry industry by use of anticoccidial compounds, but it ...
H D, Danforth, P C, Augustine
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Abstract The humoral antibody response to infection with the intracellular protozoan Toxoplasma gondii was suppressed in adult mice that had been injected with antiserum formed against the same parasite. A small proportion of the mice developed a state of tolerance to Toxoplasma, demonstrable by the absence of Toxoplasma antibody in ...
F G, Araujo, J S, Remington
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A sensitive immunoassay for detecting antibodies to the protozoan parasite of poultry Eimeria tenella, has been developed. Microspheres coated with parasite antigen are reacted with antibody-containing chicken serum followed by a fluorescent labeled second antibody and analyzed by flow cytometry.
B A, Zemcik, P K, Murray, T T, MacDonald
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