Results 121 to 130 of about 10,579 (219)

Off‐The‐Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma

Advanced Materials, EarlyView.
A star‐shaped cross‐linked polyglutamate (StCl) nanocarrier delivers melanoma‐associated peptide antigens via redox‐responsive linkers, inducing lymph node‐targeted antigen presentation. The nanoconjugate activates dendritic cells, promotes effector T‐cell responses, and enables tumor regression even in humanized patient‐derived preclinical models ...
Liane IF Moura, Alessio Malfanti, Ana I Matos, Carina Peres, Ana Armiñán, Aroa Duro‐Castaño, Inmaculada Conejos‐Sánchez, María Medel, Snežana Đorđević, Paula Carrascosa, Bárbara Carreira, Rita C Acúrcio, Helena Xavier‐Ferreira, Alberto Hernández‐Barranco, Elena Castellano, Esther Roselló, José C. Machado, Héctor Peinado, María J. Vicent, Helena F. Florindo   +19 more
wiley   +1 more source

Micro‐ and Nano‐Bots for Infection Control

Advanced Materials, EarlyView.
This review presents a strategic vision for integrating micro‐ and nanobots in the pipeline for infection diagnosis, prevention, and treatment. To develop these robots as a practical solution for infection management, their design principles are clarified based on their propulsion mechanisms and then categorized infection management domains based on ...
Azin Rashidy Ahmady, Shadman Khan, Hong Han, Wei Gao, Zeinab Hosseinidoust, Tohid F. Didar   +5 more
wiley   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

Advanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding, Bing Liu, Andreas Peil, Sisi Fan, Jie Chao, Na Liu   +5 more
wiley   +1 more source

Antibody and complement-dependent viral neutralization [PDF]

Springer Seminars in Immunopathology, 1979
Raymond M. Welsh, Neil R. Cooper
openaire   +3 more sources

Concepts and methods for predicting viral evolution [PDF]

arXiv
The seasonal human influenza virus undergoes rapid evolution, leading to significant changes in circulating viral strains from year to year. These changes are typically driven by adaptive mutations, particularly in the antigenic epitopes, the regions of the viral surface protein haemagglutinin targeted by human antibodies. Here we describe a consistent
arxiv  

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

Advanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania, Manus J. P. Biggs, Katarzyna Krukiewicz   +2 more
wiley   +1 more source

Ag‐Cu Nanoarchitecture for Enhanced LSPR Absorption: the Role of Surface Roughness and near‐field Interactions

Advanced Materials Interfaces, EarlyView.
This study investigates the plasmonic properties and biosensing capabilities of a nanocomposite incorporating Cu and Ag nanoparticles for detecting anti‐DbpA antibodies associated with Lyme disease. The enhanced LSPR response is explained through FDTD simulations of Cu–Ag near‐field interactions and increased surface roughness.
Sanjay Kumar, Pavel Curda, Hana Maskova, Lenka Doudová, Pavel Pleskunov, Anna Kuzminova, Libor Hejduk, Jan Sterba, Ondřej Kylián, Ryan O. M. Rego, Vitezslav Stranak   +10 more
wiley   +1 more source

Antibiotic‐Mediated Plasmonic‐Mie Resonance for Biosensing Applications on a Novel Silicon Nanopillar Metasurface

Advanced Materials Interfaces, EarlyView.
Unique nanopillar metasurfaces are fabricated for the purpose of sensitive detection to refractive index changes in the presence of gold nanoparticles. The addition of these nanoparticles to the surface of the silicon nanopillars is facilitated via a novel antibiotic‐mediated linker system to promote localized surface plasmon effects resulting from Mie
Jacob Waitkus, JaeWoo Park, Theodore Ndukaife, Sui Yang, Ke Du   +4 more
wiley   +1 more source

Multi-point Infection Dynamics of Hepatitis B in the Presence of Sub-Viral Particles [PDF]

arXiv
Hepatitis B virus (HBV) is considered as etiological agent of the lethal liver disease hepatitis B. Globally, hepatitis B is recognized as one of the prevailing infectious diseases with a significant impact on human health. In spite of being non-infectious in nature, sub-viral particles (SVPs) , composed with mainly viral surface proteins, play ...
arxiv  

Computationally Guided Liquid Crystal‐Based Competitive Binding Sensing Platform for Optical Detection of Spike Protein

Advanced Materials Technologies, EarlyView.
A competitive‐binding paradigm for detection of viruses with the detection of the receptor binding domain of the spike protein as an illustrative example is introduced. Importantly, this approach does not rely on antibodies and therefore is of significance for detecting novel and emerging pathogens. Abstract A liquid crystal (LC)‐based sensing platform
Homa Ghaiedi, Shubham Pandey, Sophia Ezendu, Tibor Szilvási, Karthik Nayani   +4 more
wiley   +1 more source