Results 21 to 30 of about 2,860,326 (352)

Viral antibodies in infectious mononucleosis [PDF]

FEMS Immunology & Medical Microbiology, 1994
Patients with Epstein-Barr virus (EBV) infectious mononucleosis (IM) usually develop heterophilic antibodies and some autoantibodies. Antibodies to rubella, measles, adeno-, entero-, herpes simplex, cytomegalo- and varicella-zoster viruses were titrated in sera from IM patients and matched healthy controls using the complement fixation test (CFT) and ...
May Britt Kalvenes, Birgitte Boye, Bjørg Viggen, Gunnar Haukenes, Karl-Henning Kalland, Reinhardt W. Flø   +5 more
openaire   +3 more sources

SARS-CoV-2 neutralizing antibodies; longevity, breadth, and evasion by emerging viral variants

medRxiv, 2020
The SARS-CoV-2 antibody neutralization response and its evasion by emerging viral variants are unknown. Antibody immunoreactivity against SARS-CoV-2 antigens and Spike variants, inhibition of Spike-driven virus-cell fusion, and infectious SARS-CoV-2 ...
F. Tea, A. Stella, A. Aggarwal, David R Darley, D. Pilli, D. Vitale, V. Merheb, Fiona X. Z. Lee, P. Cunningham, G. Walker, David A. Brown, W. Rawlinson, Sonia R Isaacs, Vennila Mathivanan, Markus Hoffman, Stefan Pöhlmann, Dominic E. Dwyer, Rebeca Rockett, V. Sintchenko, Veronica C. Hoad, D. Irving, G. Dore, Iain B. Gosbell, A. Kelleher, G. Matthews, F. Brilot, S. Turville   +26 more
semanticscholar   +1 more source

Efficient evolution of human antibodies from general protein language models

Nature Biotechnology, 2023
A general protein language model guides protein evolution with 20 or fewer variants needed for testing. Natural evolution must explore a vast landscape of possible sequences for desirable yet rare mutations, suggesting that learning from natural ...
Brian L. Hie, Varun R. Shanker, Duo Xu, Theodora U. J. Bruun, P. Weidenbacher, Shaogeng Tang, Wesley Wu, J. Pak, Peter S. Kim   +8 more
semanticscholar   +1 more source

Detection of Anti-Nucleocapsid Antibody in COVID-19 Patients in Bangladesh Is not Correlated with Previous Dengue Infection

Pathogens, 2021
Background: The assessment of antibody responses to severe acute respiratory syndrome coronavirus-2 is potentially confounded by exposures to flaviviruses. The aims of the present research were to determine whether anti-dengue antibodies affect the viral
Simon D. Lytton, Mahmuda Yeasmin, Asish Kumar Ghosh, Md. Rakibul Hassan Bulbul, Md. Maruf Ahmed Molla, Martha Herr, Helmut Duchmann, Md. Mohiuddin Sharif, Tasnim Nafisa, Md. Robed Amin, Nur Hosen, Md. Tanvir Rahman, Sumaiya Islam, Alimul Islam, Abul Khair Mohammad Shamsuzzaman   +14 more
doaj   +1 more source

Engineered antibodies to combat viral threats [PDF]

Nature, 2020
As the COVID-19 pandemic rages globally, interest in antiviral treatments has never been higher. Antibodies are key defence components, and engineering them to better exploit their natural functions might boost therapeutic options. Modification of the antibody Fc domain boosts defence responses.
Cragg, Mark, Yu, Xiaojie
openaire   +4 more sources

Protective mechanisms of nonneutralizing antiviral antibodies.

PLoS Pathogens, 2023
Antibodies that can bind to viruses but are unable to block infection in cell culture are known as "nonneutralizing antibodies." Such antibodies are nearly universally elicited following viral infection and have been characterized in viral infections ...
Tawny L Chandler, Agnes Yang, Claire E Otero, Sallie R Permar, Sarah L Caddy   +4 more
doaj   +1 more source

Viral Antibodies in Chronic Fatigue Syndrome [PDF]

Clinical Infectious Diseases, 1995
Item does not contain ...
Swanink, C.M.A., Vercoulen, J.H.M.M., Bazelmans, H.M., Fennis, J.F.M., Bleijenberg, G., Meer, J.W.M. van der, Galama, J.M.D.   +6 more
openaire   +6 more sources

Complete mapping of viral escape from neutralizing antibodies. [PDF]

PLoS Pathogens, 2017
Identifying viral mutations that confer escape from antibodies is crucial for understanding the interplay between immunity and viral evolution. We describe a high-throughput approach to quantify the selection that monoclonal antibodies exert on all ...
Michael B Doud, Scott E Hensley, Jesse D Bloom   +2 more
doaj   +1 more source

Viral interference with antibody and complement

Seminars in Cell & Developmental Biology, 1998
Viruses have evolved strategies to evade immunity mediated by antibody and complement. Herpesviruses and coronaviruses encode IgG Fc binding proteins that inhibit IgG activity, enabling the virus or infected cell to escape antibody attack. Herpesviruses, vaccinia virus and HIV-1 have the capacity to interfere with complement, either by incorporation of
Harvey M. Friedman, Thandavarayan Nagashunmugam, John M. Lubinski   +2 more
openaire   +2 more sources

Combination of rRT-PCR and Anti-Nucleocapsid/Anti-Spike Antibodies to Characterize Specimens with Very Low Viral SARs-CoV-2 Load: A Real-Life Experience

Microorganisms, 2021
The objective of the present study was to evaluate the true positivity among people, whose results of initial testing of nasopharyngeal swabs (NPS) showed a very low viral load of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Zoe Florou, Meropi Zigra, Philippos Kartalidis, Katerina Tsilipounidaki, Georgia Papadamou, Aikaterini Belia, George C. Fthenakis, Efthymia Petinaki   +7 more
doaj   +1 more source