Results 31 to 40 of about 932,790 (307)

Monoclonal anti-envelope antibody AP33 protects humanized mice against a patient-derived hepatitis C virus challenge [PDF]

open access: yes, 2016
End-stage liver disease caused by hepatitis C virus (HCV) infection is a major indication for liver transplantation. However, immediately after transplantation the liver graft of viremic patients universally becomes infected by circulating virus ...
Baumert, Thomas F.   +12 more
core   +2 more sources

Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways

open access: yesiScience, 2022
Summary: The rapid spread of SARS-CoV-2 variants poses a constant threat of escape from monoclonal antibody and vaccine countermeasures. Mutations in the ACE2 receptor binding site on the surface S protein have been shown to disrupt antibody binding and ...
Fangzhu Zhao   +22 more
doaj   +1 more source

The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state [PDF]

open access: yes, 2016
Indexación: Web of ScienceWith about 350 million people chronically infected around the world hepatitis B is a major health problem. Template for progeny HBV synthesis is the viral genome, organized as a minichromosome (cccDNA) inside the hepatocyte ...
Alarcon, V   +9 more
core   +2 more sources

Antibody therapies for the prevention and treatment of viral infections

open access: yesnpj Vaccines, 2017
Antibodies are an important component in host immune responses to viral pathogens. Because of their unique maturation process, antibodies can evolve to be highly specific to viral antigens.
Georgina Salazar   +3 more
doaj   +1 more source

Interleukins as one of possible markers for early diagnosis of viral hepatitis c at first year old children

open access: yesЖурнал инфектологии, 2014
The article presents the results of the research of improvement one of possible methods of early diagnostics of viral hepatitis C at first-year old children, who born from mothers with chronic viral hepatitis C, in blood anti-HCV IgG are revealed, based ...
T. A. Kirsanova
doaj   +1 more source

Characterization of the Interaction between the Herpes Simplex Virus Type I Fc Receptor and Immunoglobulin G [PDF]

open access: yes, 1999
Herpes simplex virus type I (HSV-1) virions and HSV-1-infected cells bind to human immunoglobulin G (hIgG) via its Fc region. A complex of two surface glycoproteins encoded by HSV-1, gE and gI, is responsible for Fc binding.
Bjorkman, Pamela J.   +5 more
core   +1 more source

Virological and Serological Discordant Profiles in COVID-19 Pneumonia: Two Atypical Clinical Cases

open access: yesFrontiers in Immunology, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is primarily diagnosed through viral RNA positivity in nasopharyngeal swabs, and it is associated with the early detection of specific immunoglobulins to SARS-CoV-2 proteins.
Martina Ranzenigo   +5 more
doaj   +1 more source

Epidemiological evidence of acute transmission of Zika virus infection in dengue suspected patients in Sri-Lanka

open access: yesJournal of Infection and Public Health, 2023
Background: Zika Virus (ZIKV) is a re-emerging, arthropod-borne flavivirus transmitted by Aedes mosquitoes (Ae. aegypti and Ae. albopictus). The coexistence of dengue virus (DENV) and ZIKV concurrently has been associated with a wide array of ...
Mya Myat Ngwe Tun   +9 more
doaj   +1 more source

Single-domain antibodies and their formatting to combat viral infections [PDF]

open access: yes, 2018
Since their discovery in the 1990s, single-domain antibodies (VHHs), also known as NanobodiesA (R), have changed the landscape of affinity reagents. The outstanding solubility, stability, and specificity of VHHs, as well as their small size, ease of ...
Ballegeer, Marlies   +4 more
core   +2 more sources

An investigation of the breadth of neutralising antibody response in cats naturally infected with feline immunodeficiency virus [PDF]

open access: yes, 2015
Neutralising antibodies (NAbs) are believed to comprise an essential component of the protective immune response induced by vaccines against FIV and HIV infections.
Beczkowski, Pawel   +5 more
core   +2 more sources

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