Results 31 to 40 of about 288,682 (209)

Using the nonhuman primate model of HCMV to guide vaccine development. [PDF]

, 2014
The natural history of human cytomegalovirus (HCMV) is inextricably associated with mucosal surfaces. The vast preponderance of primary infections occur following mucosal exposure to infectious virions, and the high seroprevalence of HCMV throughout the ...
Barry, Peter A, Deere, Jesse D
core   +3 more sources

A Broadly Reactive Human Anti-hemagglutinin Stem Monoclonal Antibody That Inhibits Influenza A Virus Particle Release

EBioMedicine, 2017
Many broadly reactive human monoclonal antibodies against the hemagglutinin (HA) stem of influenza A virus have been developed for therapeutic applications.
Seiya Yamayoshi, Ryuta Uraki, Mutsumi Ito, Maki Kiso, Sumiho Nakatsu, Atsuhiro Yasuhara, Kohei Oishi, Tadahiro Sasaki, Kazuyoshi Ikuta, Yoshihiro Kawaoka   +9 more
doaj   +1 more source

Novel ACE2 fusion protein with adapting activity against SARS-CoV-2 variants in vitro

Frontiers in Immunology, 2023
Despite the successful development of vaccines and neutralizing antibodies to limit the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerging variants prolong the pandemic and emphasize the persistent need to develop effective ...
Latifa Zekri, Latifa Zekri, Latifa Zekri, Latifa Zekri, Natalia Ruetalo, Mary Christie, Carolin Walker, Carolin Walker, Timo Manz, Timo Manz, Hans-Georg Rammensee, Hans-Georg Rammensee, Hans-Georg Rammensee, Helmut R. Salih, Helmut R. Salih, Helmut R. Salih, Michael Schindler, Gundram Jung, Gundram Jung, Gundram Jung   +19 more
doaj   +1 more source

Molecular and serological evidence of chikungunya virus among dengue suspected patients in Sri Lanka

Journal of Infection and Public Health
Background: Chikungunya virus (CHIKV), transmitted by Aedes mosquitoes, causes significant morbidity characterized by acute febrile illness to chronic and permanent disability in some patients.
Mya Myat Ngwe Tun, Maurine Mumo Mutua, Shingo Inoue, Yuki Takamatsu, Satoshi Kaneko, Takeshi Urano, Rohitha Muthugala, Lakkumar Fernando, Menaka Hapugoda, YINS Gunawardene, Kouichi Morita   +10 more
doaj   +1 more source

A Novel, Comprehensive A129 Mouse Model for Investigating Dengue Vaccines and Evaluating Pathogenesis

Vaccines, 2023
In search of a mouse model for use in evaluating dengue vaccines, we assessed A129 mice that lacked IFN-α/β receptors, rendering them susceptible to dengue virus (DENV) infection.
Mya Myat Ngwe Tun, Khine Mya Nwe, Jean Claude Balingit, Yuki Takamatsu, Shingo Inoue, Basu Dev Pandey, Takeshi Urano, Michinori Kohara, Kyoko Tsukiyama-Kohara, Kouichi Morita   +9 more
doaj   +1 more source

Respiratory antiviral immunity and immunobiotics: Beneficial effects on inflammation-coagulation interaction during influenza virus infection [PDF]

, 2016
Influenza virus (IFV) is a major respiratory pathogen of global importance, and the cause of a high degree of morbidity and mortality, especially in high-risk populations such as infants, elderly, and immunocompromised hosts.
Alvarez, Gladis Susana, Kitazawa, Haruki, Villena, Julio Cesar, Zelaya, María Hortensia del Rosario   +3 more
core   +1 more source

Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein [PDF]

, 2014
Infections with human respiratory syncytial virus (HRSV) occur globally in all age groups and can have devastating consequences in young infants. We demonstrate that a vaccine based on the extracellular domain (SHe) of the small hydrophobic (SH) protein ...
Bert Schepens, Brian Gilbert, Cherrie AH, Connors M, Glezen WP, Kenny Roose, Koen Sedeyn, Liesbeth Vande Ginste, Lieselot Houspie, Marc Van Ranst, Michael Schotsaert, Mills JT, Nicholas JA, Nico Rooijen, Olmsted RA, Pedro Piedra, Sarah De Baets, Ventre K, Walter Fiers, Whitehead SS, Xavier Saelens   +20 more
core   +3 more sources

Humoral and Mucosal Antibody Response to RSV Structural Proteins in RSV-Infected Adult Hematopoietic Cell Transplant (HCT) Recipients

Viruses, 2021
Respiratory syncytial virus (RSV) is an important cause of lower respiratory tract infection in infants, the elderly, and immunocompromised patients. RSV antibodies play a role in preventing reinfection and in clearance of RSV, but data regarding the ...
Xunyan Ye, Obinna P. Iwuchukwu, Vasanthi Avadhanula, Letisha O. Aideyan, Trevor J. McBride, David M. Henke, Kirtida D. Patel, Felipe-Andres Piedra, Laura S. Angelo, Dimpy P. Shah, Roy F. Chemaly, Pedro A. Piedra   +11 more
doaj   +1 more source

Detection of antibody-dependent complement mediated inactivation of both autologous and heterologous virus in primary HIV-1 infection [PDF]

, 2005
Specific CD8 T-cell responses to human immunodeficiency virus type 1 (HIV-1) are induced in primary infection and make an important contribution to the control of early viral replication.
Aasa-Chapman, M.M.I., Aubin, K., Borrow, P., Cornforth, D., Holuigue, S., Jones, N.A., McKnight, A., Newton, P., Pellegrino, P., Williams, I., Wong, M.   +10 more
core  

High prevalence of antibodies to human herpesvirus 8 in relatives of patients with classic Kaposi's sarcoma from Sardinia [PDF]

, 1998
A survey for antibodies to a recombinant small viral capsid antigen (sVCA) of human herpesvirus type 8 (HHV‐8) was conducted in Sardinia, one of the world's highest incidence areas for classic Kaposi's sarcoma (KS). Prevalence of antibodies to HHV‐8 sVCA
Angeloni, Antonio, Cerimele, Decio, Cottoni, Francesca Maria Giovanna, Faggioni, Alberto, Heston, Lee, Lin, Su-Fang, Masala, Maria Vittoria, Miller, George, Rigsby, Michael, Sirianni, Maria Caterina, Sun, Ren, Uccini, Stefania   +11 more
core   +1 more source