Results 41 to 50 of about 494,114 (145)
Understudied Factors Influencing Fc-Mediated Immune Responses against Viral Infections
Vaccines, 2019 Antibodies play a crucial role in host defense against viruses, both by preventing infection and by controlling viral replication. Besides their capacity to neutralize viruses, antibodies also exert their antiviral effects by crystallizable fragment (Fc)-
Sai Priya Anand, Andrés Finzi
doaj +1 more source
VirScan: High-throughput Profiling of Antiviral Antibody Epitopes
Bio-Protocol, 2022 Profiling the specificities of antibodies can reveal a wealth of information about humoral immune responses and the antigens they target. Here, we present a protocol for VirScan, an application of the phage immunoprecipitation sequencing (PhIP-Seq ...
Ellen Shrock +2 more
doaj +1 more source
Viral antibody dynamics in a chiropteran host [PDF]
Journal of Animal Ecology, 2013 SummaryBats host many viruses that are significant for human and domestic animal health, but the dynamics of these infections in their natural reservoir hosts remain poorly elucidated.In these, and other, systems, there is evidence that seasonal life‐cycle events drive infection dynamics, directly impacting the risk of exposure to spillover hosts ...
Baker, K.S. +10 more
openaire +6 more sources
A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy.
PLoS Pathogens, 2022 Many SARS-CoV-2 variants have mutations at key sites targeted by antibodies. However, it is unknown if antibodies elicited by infection with these variants target the same or different regions of the viral spike as antibodies elicited by earlier viral ...
Allison J Greaney +13 more
doaj +1 more source
Journal of Infection and Public Health, 2023 Background: Zika Virus (ZIKV) is a re-emerging, arthropod-borne flavivirus transmitted by Aedes mosquitoes (Ae. aegypti and Ae. albopictus). The coexistence of dengue virus (DENV) and ZIKV concurrently has been associated with a wide array of ...
Mya Myat Ngwe Tun +9 more
doaj
Antibody-mediated prevention and treatment of HIV-1 infection
Retrovirology, 2018 Novel broadly neutralizing antibodies targeting HIV-1 hold promise for their use in the prevention and treatment of HIV-1 infection. Pre-clinical results have encouraged the evaluation of these antibodies in healthy and HIV-1-infected humans.
Henning Gruell, Florian Klein
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2021 Antibodies can provide antiviral protection through neutralization and recruitment of innate effector functions through the Fc domain. While neutralization has long been appreciated for its role in antibody-mediated protection, a growing body of work ...
Bronwyn M. Gunn, Shuangyi Bai
doaj +1 more source
Viruses, 2012 The immune response against some viral pathogens, in particular those causing chronic infections, is often ineffective notwithstanding a robust humoral neutralizing response.
Roberto Burioni +8 more
doaj +1 more source
Viral antibody studies in pancreatic disease. [PDF]
Gut, 1975 Viral studies were performed on sera from 54 patients with recent acute pancreatitis, 10 with recurrent acute pancreatitis, seven with chronic pancreatitis, and 10 with pancreatic carcinoma, and on sera from 81 age- and sex-matched controls. In 29 of the acute pancreatitis patients from whom paired sera were obtained no convincing evidence of recent ...
D J Jeffries +3 more
openaire +3 more sources
Neutralizing Antibodies and Pathogenesis of Hepatitis C Virus Infection
Viruses, 2012 Hepatitis C virus (HCV) infection is a major cause of chronic liver disease worldwide. The interplay between the virus and host innate and adaptive immune responses determines the outcome of infection.
Françoise Stoll-Keller +8 more
doaj +1 more source