Results 71 to 80 of about 729,991 (222)

Antigen flexibility supports the avidity of hemagglutinin-specific antibodies at low antigen densities.

PLoS Pathogens
The receptor-binding protein of influenza A virus, hemagglutinin (HA), is the most abundant protein on the viral surface. While high densities of HA are thought to improve cellular attachment by increasing avidity for the viral receptor, they may also ...
Ananya Benegal, Yuanyuan He, Katilyn Ho, Giselle Groff, Zijian Guo, Michael D Vahey   +5 more
doaj   +1 more source

Antibody-mediated prevention and treatment of HIV-1 infection

Retrovirology, 2018
Novel broadly neutralizing antibodies targeting HIV-1 hold promise for their use in the prevention and treatment of HIV-1 infection. Pre-clinical results have encouraged the evaluation of these antibodies in healthy and HIV-1-infected humans.
Henning Gruell, Florian Klein
doaj   +1 more source

Enzyme-linked immunosorbent assay using a virus type-specific peptide based on a subdomain of envelope protein e(rns) for serologic diagnosis of pestivirus infections in swine

, 2001
Peptides deduced from the C-terminal end (residues 191 to 227) of pestivirus envelope protein Erns were used to develop enzyme-linked immunosorbent assays (ELISAs) to measure specifically antibodies against different types of pestiviruses.
Langedijk, J.P., Smit, J.A., de, Meloen, R.H., Middel, W.G., Kramps, J.A., de Smit, J.A.   +5 more
core   +1 more source

When viral infections meet the anti-MDA5 antibody-positive dermatomyositis

Frontiers in Immunology
Anti-melanoma differentiation-related gene 5 (MDA5) antibody-positive dermatomyositis (anti-MDA5+ DM) is recognized as a distinct subtype of dermatomyositis, characterized by its frequent association with interstitial lung disease (ILD), particularly ...
Shuzi Liu, Zheng Zhao, Yabin Li, Yao Tan, Huabin Tian, Fei Xie   +5 more
doaj   +1 more source

Neutralization Interfering Antibodies: A “Novel” Example of Humoral Immune Dysfunction Facilitating Viral Escape?

Viruses, 2012
The immune response against some viral pathogens, in particular those causing chronic infections, is often ineffective notwithstanding a robust humoral neutralizing response.
Roberto Burioni, Laura Solforosi, Massimo Clementi, Roberta A. Diotti, Matteo Castelli, Elena Criscuolo, Nicola Clementi, Giuseppe Sautto, Mancini Nicasio   +8 more
doaj   +1 more source

No association between islet cell antibodies and coxsackie B, mumps, rubella and cytomegalovirus antibodies in non-diabetic individuals aged 7–19 years [PDF]

, 1991
Viral antibodies were tested in a cohort of 44 isletcell antibody-positive individuals age 7–19 years, and 44 of their islet cell antibody-negative age and sex-matched classmates selected from a population study of 4208 pupils who had been screened for ...
Muir, Peter, Glück, Michael, Seißler, Jochen, Heinze, Eberhard, Hampl, Walter, Egle, H., Pfeiffer, Ernst Friedrich, Böhm, Bernhard Otto, Banatvala, Jangu E., Scherbaum, Werner A., Hauner, Hans   +10 more
core   +1 more source

Developing recombinant antibodies by phage display technology to neutralize viral infectious diseases

SLAS Discovery
The use of recombinant antibodies developed through phage display technology offers a promising approach for combating viral infectious diseases. By specifically targeting antigens on viral surfaces, these antibodies have the potential to reduce the ...
Mujahed I. Mustafa, Ahmed Mohammed
doaj   +1 more source

Risk factors for Marburg hemorrhagic fever, Democratic Republic of the Congo. [PDF]

, 2003
We conducted two antibody surveys to assess risk factors for Marburg hemorrhagic fever in an area of confirmed Marburg virus transmission in the Democratic Republic of the Congo.
Roth, Cathy, Ksiazek, T. G., Grein, Thomas, Bausch, Daniel G, Kond\ue9, Kader M., Ben Tugume, Modeste L. Libande, Pirard, Patricia, Pierre E. Rollin, Tugume, B., Colebunders, Robert, Bausch, Daniel G., Muyembe-Tamfum, Jean-Jacques, Olinda, L. L., Rodier, G. R., Matthias Borchert, Kondé, Kader M, Talarmin, A., Ksiazek, Thomas G, Borchert, M., Rollin, P. E., Daniel G. Bausch, Pirard, P., Bausch, D. G., Rollin, Pierre E, Thomas G. Ksiazek, Rodier, Guénaël R, Swanepoel, R., Ksiazek, Thomas G., Swanepoel, Robert, Kader M. Kondé, Campbell, P., Campbell, Patricia, Thomas Grein, Libande, Modeste L, Grein, T., Muyembe-Tamfum, J. J., Robert Colebunders, Robert Swanepoel, Jean-Jacques Muyembe-Tamfum, Patricia Pirard, Oyewale Tomori, Patricia Campbell, Tomori, Oyewale, Cathy Roth, Loku L. Olinda, Tugume, Ben, Colebunders, R., Talarmin, Antoine, Roth, C., Libande, M. L., Bertherat, E., Libande, Modeste L., Guénaël R. Rodier, Pirad, Patricia, Olinda, Loku L., Antoine Talarmin, Kondé, K. M., Rollin, Pierre E., Eric Bertherat, Tomori, O., Borchert, Matthias, Bertherat, Eric, Olinda, Loku L, Rodier, Gu\ue9na\uebl R.   +64 more
core   +1 more source

Characterization and application of monoclonal antibodies against turbot (Scophthalmus maximus) rhabdovirus [PDF]

, 2006
Five monoclonal antibodies (mAbs), 1G8, 1H9, 2D2, 2D3, and 2F5, against Scophthalmus maximus rhabdovirus (SMRV) were prepared. Characterization of the mAbs included indirect enzyme-linked immunosorbent assay, isotyping, viral inhibition assay ...
Zhang, Qi-Ya, Zhang, QY, Chinese Acad Sci, Grad Sch, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China, Li, Zheng-Qiu, Zhou, Guang-Zhou   +3 more
core   +1 more source

Neutralizing Antibodies and Pathogenesis of Hepatitis C Virus Infection

Viruses, 2012
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease worldwide. The interplay between the virus and host innate and adaptive immune responses determines the outcome of infection.
Françoise Stoll-Keller, Thomas F. Baumert, Laura Heydmann, Isabel Fofana, Quentin Lepiller, Daniel J. Felmlee, Samira Fafi-Kremer, Mirjam B. Zeisel, Catherine Fauvelle   +8 more
doaj   +1 more source