Results 251 to 260 of about 602,416 (352)

Expression of antibody-drug conjugate targets in post-mortem samples of breast cancer metastases and normal tissue. [PDF]

Nat Commun
Borremans K, Pabba A, Zels G, Mahdami A, Carette C, Maetens M, Van Baelen K, Van Cauwenberge J, Nguyen HL, Izci H, Leduc S, Hatse S, Nysen M, Boeckx B, Vanderheyden E, Brussel TV, Derouane F, Punie K, Van Den Bogaert W, Vermeulen P, Biganzoli E, Lambrechts D, Neven P, Wildiers H, Floris G, Richard F, Desmedt C.   +26 more
europepmc   +1 more source

Figure S3 from Development of a Novel DNA Mono-alkylator Platform for Antibody–Drug Conjugates

Joshua D. Thomas, Aleksandr V. Yurkovetskiy, Mao Yin, Natalya D. Bodyak, Shuyi Tang, Marina Protopopova, Eugene Kelleher, Brian Jones, Liping Yang, Daniel Custar, Kalli C. Catcott, Damon R. Demady, Scott D. Collins, Ling Xu, Charlie Bu, LiuLiang Qin, Elena Ter‐Ovanesyan, Marc Damelin, Dorin Toader, Timothy B. Lowinger   +19 more
openalex   +1 more source

Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies

Advanced Functional Materials, EarlyView.
A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta, Sofia Peressotti, Roberto Portillo‐Lara, Josef Goding, Rylie Green   +4 more
wiley   +1 more source

Harnessing computational technologies to facilitate antibody-drug conjugate development. [PDF]

Nat Chem Biol
Croitoru A, Orr AA, MacKerell AD.
europepmc   +1 more source

Supplementary Figure S1 from MYTX-011: A pH-Dependent Anti–c-MET Antibody–Drug Conjugate Designed for Enhanced Payload Delivery to c-MET–Expressing Tumor Cells

Nimish Gera, Kyle M. Fitzgerald, Vijay Ramesh, Purvi Patel, Deepak Kanojia, Federico Colombo, Lena Kien, Simon Aoyama, Lihui Xu, Jussekia Jean, Amit M. Deshpande, William C. Comb, Thomas Chittenden, Brian P. Fiske   +13 more
openalex   +1 more source

High‐Resolution Characterization of Protein‐Conjugated, mRNA‐Loaded Lipid Nanoparticles by Analytical Ultracentrifugation

Advanced Functional Materials, EarlyView.
Lipid nanoparticles containing messenger RNA are characterized by sedimentation velocity analytical ultracentrifugation using UltraScan's new Custom Grid algorithm to provide multi‐dimensional distributions for partial specific volume (particle density), molar mass, sedimentation, diffusion, and hydrodynamic radius.
Sophia Bird, Connor Smith, Nahal Habibi, Samantha Rivera, Saeed Mortezazadeh, Reece Martin, Benjamin M. Geilich, Gilles Besin, Borries Demeler   +8 more
wiley   +1 more source

Leveraging artificial intelligence in antibody-drug conjugate development: from target identification to clinical translation in oncology. [PDF]

NPJ Precis Oncol
Lu Y, Huang W, Li Y, Xu Y, Wei Q, Sha C, Guo P.   +6 more
europepmc   +1 more source

Supplementary Fig.S1 from Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for treatment of Nectin-4-expressing Cancers

Wei Zhou, Peng Fang, Dongan Yu, Hongyuan Ren, Meng You, Long Yin, Fei Mei, Huikai Zhu, Zhenzhen Wang, Hui Xu, Yuxia Cao, Xiaowei Sun, Xiaohong Xu, Jianjun Bi, Jin Wang, Lanping Ma, Xin Wang, Lin Chen, Yongliang Zhang, Xiaowei Cen, Xi Zhu, Liguang Lou, Datao Liu, Xiaoding Tan, Jinliang Yang, Tao Meng, Jingkang Shen   +26 more
openalex   +1 more source

Cold Quad‐Modal Nanocomplex for Precise and Quantitative In Vivo Stem Cell Tracking

Advanced Functional Materials, EarlyView.
Multimodal albumin–bismuth sulfide–superparamagnetic iron oxide (ABS) nanocomplexes are developed for stem cell tracking across four different imaging modalities: MRI, MPI, MSOT, and CT. Combining its flexibility with high sensitivity, this quad‐modal imaging agent enables a robust quantification of ABS‐labeled stem cells in vivo.
Ali Shakeri‐Zadeh, Chao Wang, Shreyas Kuddannaya, Saleem Yousf, Jeff W. M. Bulte   +4 more
wiley   +1 more source

Preclinical Characterization of XB010: A Novel Antibody-Drug Conjugate for the Treatment of Solid Tumors that Targets Tumor-Associated Antigen 5T4. [PDF]

Mol Cancer Ther
Mendelsohn BA, Gogas KR, Higaki JN, Solis WA, Vainshtein I, Cheng J, Park M, Hennessy MA, Janson CM, Matsuda Y, Barfield RM, Drake PM, Chuprakov S, Hickle CL, Linz T, Bauzon M, Yeo DY, Zhang F, Ogunkoya AO, Kantak S.   +19 more
europepmc   +1 more source