Results 281 to 290 of about 589,804 (355)

Light‐Responsive Enzyme‐Loaded Nanoparticles for Tunable Adhesion and Mechanical Wound Contraction

Advanced Functional Materials, EarlyView.
This study presents a photoactivatable enzyme‐loaded mesoporous nanoparticle system (MPDA_PaTy) that enables light‐triggered tunable tissue adhesion and facilitates mechanical wound contraction. Controlled enzymatic crosslinking at tissue or hydrogel interfaces allows on‐demand adhesion.
Junghyeon Ko, Hyeon‐Jin Kim, Jeong‐Uk Kim, Seh Ri Oh, Tae Hoon Kang, Junghwan Byun, Uk‐Jae Lee, Minglin Ma, Su‐Hwan Kim, Byung‐Gee Kim, Nathaniel S. Hwang   +10 more
wiley   +1 more source

A B7H3-targeting antibody-drug conjugate in advanced solid tumors: a phase 1/1b trial. [PDF]

Nat Med
Ma Y, Yang Y, Huang Y, Fang W, Xue J, Meng X, Fan Y, Fu S, Wu L, Zheng Y, Liu J, Liu Z, Zhuang W, Rosen S, Qu S, Li B, Li M, Zhao Y, Yang S, Ji Y, Sommerhalder D, Luo S, Yang K, Li J, Lv D, Zhang P, Zhao Y, Hong S, Zhang Y, Zhao S, Chin S, Zhang X, Lian W, Cai J, Xue T, Zhang L, Zhao H.   +36 more
europepmc   +1 more source

Ice Lithography: Recent Progress Opens a New Frontier of Opportunities

Advanced Functional Materials, EarlyView.
This review focuses on recent advancements in ice lithography, including breakthroughs in compatible precursors and substrates, processes and applications, hardware, and digital methods. Moreover, it offers a roadmap to uncover innovation opportunities for ice lithography in fields such as biological, nanoengineering and microsystems, biophysics and ...
Bingdong Chang, Gwendoline A. E. Anand, Rubaiyet Haque, Dylan A. Chiaro, Mona Sharma, Andrew R. Williams, Frank Niklaus, Daryl W. Yee, Gavin M. King, Anpan Han   +9 more
wiley   +1 more source

<i>F3</i> Expression Drives Sensitivity to the Antibody-Drug Conjugate Tisotumab Vedotin in Glioblastoma. [PDF]

Cancers (Basel)
Sears TK, Wang W, Drumm M, Unruh D, McCord M, Horbinski C.   +5 more
europepmc   +1 more source

Tailoring the Properties of Functional Materials With N‐Oxides

Advanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich, Michelle Kobus, Shirin Mesgarha, Erica Moretto, Laurens Grosche, Wolfgang Maison   +5 more
wiley   +1 more source

Therapy of Small Cell Lung Cancer (SCLC) with a Topoisomerase-I–inhibiting Antibody–Drug Conjugate (ADC) Targeting Trop-2, Sacituzumab Govitecan

, 2017
Jhanelle E. Gray, Rebecca S. Heist, Alexander Starodub, D. Ross Camidge, Ebenezer A. Kio, Gregory A. Masters, W. Thomas Purcell, Michael J. Guarino, Jamal Misleh, Charles Schneider, Bryan J. Schneider, Allyson J. Ocean, Tirrell Johnson, Leena Gandhi, Kevin Kalinsky, Ronald Scheff, Wells A. Messersmith, Serengulam V. Govindan, Pius Maliakal, Boyd Mudenda, William A. Wegener, Robert M. Sharkey, David M. Goldenberg   +22 more
openalex   +1 more source

Selective STING Activation in Intratumoral Myeloid Cells via CCR2-Directed Antibody-Drug Conjugate TAK-500. [PDF]

Cancer Immunol Res
Appleman VA, Matsuda A, Ganno ML, Zhang DM, Rosentrater E, Maldonado Lopez AE, Porciuncula A, Hatten T, Christensen CL, Merrigan SA, Lee HM, Lee MY, Wang CI, Dong L, Huang J, Iartchouk N, Wang J, Xu H, Yoneyama T, Piatkov KI, Haridas S, Harbison CE, Gregory RC, Parent A, Lineberry N, Arendt C, Schalper KA, Abu-Yousif AO.   +27 more
europepmc   +1 more source

3D‐Printed Soft Magnetoactive Origami Actuators

Advanced Functional Materials, EarlyView.
Soft magnetoactive films are 3D‐printed using ink with up to 75 wt.% ferromagnetic particles and dual UV/heat curing, then integrated with various origami structures. The films are flexible, magnetically responsive, and programmable, enabling flexible integration with origami without hindering shape‐changeability.
Sen Zhang, Yuan Li, Zimeng Li, Nabil Chedid, Peiqi Zhang, Ke Cheng, Xiaomeng Fang   +6 more
wiley   +1 more source

Bispecific Antibodies and Antibody–Drug Conjugates (ADCs) Bridging HER2 and Prolactin Receptor Improve Efficacy of HER2 ADCs

, 2017
Julian Andreev, Nithya Thambi, Andrés E. Perez Bay, Frank J. Delfino, Joel W. Martin, Marcus P. Kelly, Jessica R. Kirshner, Ashique Rafique, Arthur Kunz, Thomas Nittoli, Douglas MacDonald, Christopher Daly, William C. Olson, Gavin Thurston   +13 more
openalex   +1 more source

The Anti-FRα Antibody-Drug Conjugate Luveltamab Tazevibulin Demonstrates Efficacy in Non-Small Cell Lung Cancer Preclinical Models and Induces Immunogenic Cell Death. [PDF]

Mol Cancer Ther
Yuan R, McGeehan A, Zhou S, Cheng C, Armanini M, Smith J, Embry M, Pena R, Lewis DK, Hernandez G, Bajjuri K, Tran C, Yin G, Abrahams C, Li X, Gerber HP, Yam A, Kiefel H.   +17 more
europepmc   +1 more source