The antibody-drug conjugate targeting ROR1, NBE-002, is active in high-grade serous ovarian cancer preclinical models. [PDF]
Liu D+9 more
europepmc +1 more source
Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley +1 more source
Precise targeting cytotoxicity of antibody-drug conjugate combined with immunotherapy as first-line regimen for metastatic triple-negative breast cancer in ASCENT-04. [PDF]
Bian L, Zhang S, Li M, Yang J, Yin Y.
europepmc +1 more source
Spatially precise chemo-radio-immunotherapy by antibody drug conjugate directed tumor radiosensitization to potentiate immunotherapies. [PDF]
Mortaja M+4 more
europepmc +1 more source
Incidence of antibody-drug conjugate-related hepatotoxicity in breast cancer: a systematic review and meta-analysis. [PDF]
Yang P+9 more
europepmc +1 more source
The development and evaluation of a tublysine-based antibody-drug conjugate with enhanced tumor therapeutic efficacy. [PDF]
Guo H+19 more
europepmc +1 more source
Predictive Factors of Antibody-Drug Conjugate Treatment in Metastatic Breast Cancer: A Narrative Review. [PDF]
Gadaleta-Caldarola G+6 more
europepmc +1 more source
Impact of DNA repair deficiency on sensitivity to antibody-drug conjugate (ADC) payloads in bladder cancer. [PDF]
P Shanmugam S+7 more
europepmc +1 more source
Related searches:
1022 Background: Optimizing sequential use of Antibody Drug Conjugates (ADCs) is an area of unmet need and of rising clinical importance. With the recent approvals of sacituzumab govitecan (SG) for HR+/HER2- and triple negative metastatic breast cancer ...
R. Abelman+12 more
semanticscholar +1 more source