Results 361 to 370 of about 349,757 (388)

Payloads of Antibody: Drug Conjugates

2015
The payload of antibody–drug conjugates (ADCs) is the warhead of ADCs that kills the tumor cells. Three classes of highly potent toxins including maytansinoids, auristatins, and calicheamicins are currently being employed or pursued in the clinic as the payloads of ADCs.
openaire   +1 more source

Building Antibody-Drug Conjugates

Chemical & Engineering News Archive, 2014
They’re here. Antibody-drug conjugates, target-seeking molecular missiles with lethal payloads, have arrived.
openaire   +1 more source

Click Nucleophilic Conjugate Additions to Activated Alkynes: Exploring Thiol-yne, Amino-yne, and Hydroxyl-yne Reactions from (Bio)Organic to Polymer Chemistry

Chemical Reviews, 2021
Joshua C Worch, Matthew J Price, Andrew Dove   +2 more
exaly  

The antibody–drug conjugate landscape

Nature reviews. Drug discovery
Patrick M. Flynn, Smruthi Suryaprakash, Daniel Grossman, Val Panier, John Wu   +4 more
semanticscholar   +1 more source

Photoinduced chemomimetic biocatalysis for enantioselective intermolecular radical conjugate addition

Nature Catalysis, 2022
Xiaoqiang Huang, Guangde Jiang, Wesley Harrison   +2 more
exaly  

Multifunctional biocatalyst for conjugate reduction and reductive amination

Nature, 2022
Thomas W Thorpe, James R Marshall, Vanessa Harawa   +2 more
exaly  

Hodgkin lymphoma: A review and update on recent progress

Ca-A Cancer Journal for Clinicians, 2018
Satish P Shanbhag, Richard F Ambinder
exaly  

Cooperative targeting of melanoma heterogeneity with an AXL antibody-drug conjugate and BRAF/MEK inhibitors

Nature Medicine, 2018
J. Boshuizen, L. Koopman, O. Krijgsman, A. Shahrabi, Elke Gresnigt- van den Heuvel, M. Ligtenberg, David W. Vredevoogd, K. Kemper, T. Kuilman, Ji-Ying Song, N. Pencheva, J. T. Mortensen, M. G. Foppen, E. Rozeman, C. Blank, M. Janmaat, D. Satijn, E. Breij, D. Peeper, P. Parren   +19 more
semanticscholar   +1 more source

Application of Nanotechnology in Cancer Therapy and Imaging

Ca-A Cancer Journal for Clinicians, 2008
Dong M Shin
exaly  

Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens

Nature Biotechnology, 2020
Geoffrey M Lynn, Christine Sedlik, Faezzah Baharom   +2 more
exaly