Results 201 to 210 of about 2,312,760 (293)

Critical role of complement in antibody mediated rejection in kidney transplantation. [PDF]

World J Transplant
Abbas K, Mubarak M, Musharraf W, Aziz T, Zafar MN.   +4 more
europepmc   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli, Sara Alvente, Stefano Bastianini, Chiara Berteotti, Elisabetta Ciani, Elenia Cinelli, Viviana Lo Martire, Giorgio Medici, Tommaso Mello, Elena Miglioranza, Alessandro Silvani, Donatella Mutolo, Giovanna Zoccoli   +12 more
wiley   +1 more source

International Society for Heart and Lung Transplantation Scientific Statement on pulmonary antibody-mediated rejection and proposed graft, antibody, and pathology (GAP) definition. [PDF]

J Heart Lung Transplant
Calabrese F, Levine DJ, Adam BA, Agbor-Enoh S, Benden C, Budev MM, Cochrane AB, Cozzi E, Darley DR, Fishbein GA, Gelman AE, Glanville AR, Greenland JR, Hickey MJ, Ius F, Jaksch P, Jackson AM, Joerns JO, Lor H, Lowery EM, Mangiola M, Morlacchi LC, Murray MA, Nair A, Ocagli H, Parmar JS, Pavlisko EN, Perch M, Rahaghi FF, Roden AC, Roux A, Snyder L, Sweet S, Verleden SE, Visner GA, Vos R, Wikenheiser-Brokamp KA, Zeevi A, Hachem RR.   +38 more
europepmc   +1 more source

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source

Glomerular plasmalemma vesicle-associated protein-1 as an endothelial remodelling marker complementing C4d in chronic active antibody-mediated rejection. [PDF]

Histopathology
Igarashi Y, Shimokawa M, Kawanishi K, Hirai T, Seino H, Shimizu T, Ishida H, Takagi T.   +7 more
europepmc   +1 more source

Gap‐Free Cannabis sativa Assemblies Reveal Post‐Polyploid Genome Remodelling and Refine the Evolution of Cannabinoid Synthase Genes

Plant Biotechnology Journal, EarlyView.
ABSTRACT Despite the therapeutic importance of cannabinoids, the scarcity of gap‐free Cannabis genomes has limited the dissection of the genetic and genomic basis of cannabinoid biosynthesis and genome evolution. Here, we generated two haplotype‐phased, gap‐free, gold‐standard assemblies and used them to investigate post‐polyploid genome remodelling ...
Jiangjiang Zhang, Chuchu Qin, Zhao Li, Lining Zhao, Ashok Biswas, Touming Liu, Mingbao Luan, Lin Li, Defang Li, Jianbin Yan   +9 more
wiley   +1 more source

Contemporary Antibody-Mediated Rejection in Heart Transplantation: JACC: Heart Failure Position Statement. [PDF]

JACC Heart Fail
Mehta A, DeFilippis EM, Stehlik J, Jackson AM, Kobashigawa JA, Shah P.   +5 more
europepmc   +1 more source

Cis‐urocanic acid formation following far‐UVC exposure and associated signaling responses in keratinocytes

Photochemistry and Photobiology, EarlyView.
Far‐UVC (200–235 nm) has emerged as a safe and effective indoor disinfection tool, but effects on skin immunomodulation remain unclear. This study demonstrates that 222 nm far‐UVC converts trans‐urocanic acid (UCA) to its biologically active cis isomer at levels comparable with solar radiation. In keratinocytes, far‐UVC alone caused modest increases in
Lizzie Thomas, Gareth Hazell, Katarzyna Baczynska, Jinkang Zhang, Paul O'Mahoney   +4 more
wiley   +1 more source

The tissue is the issue: Going beyond histopathology in antibody-mediated rejection in heart transplant patients. [PDF]

J Heart Lung Transplant
Mansouri P, Kim PJ.
europepmc   +1 more source