Results 1 to 10 of about 8,474,282 (288)

Management of donor-specific antibodies in lung transplantation [PDF]

Frontiers in Transplantation, 2023
The formation of antibodies against donor human leukocyte antigens poses a challenging problem both for donor selection as well as postoperative graft function in lung transplantation.
William Brandon, Colin Dunn, Srinivas Bollineni, John Joerns, Adrian Lawrence, Manish Mohanka, Irina Timofte, Fernando Torres, Vaidehi Kaza   +8 more
doaj   +6 more sources

The role of C4d and donor specific antibodies in face and hand transplantation—a systematic review [PDF]

Frontiers in Transplantation
To date, little is known about the mechanisms of rejection in vascularized composite allotransplantation, particularly for antibody mediated rejection.
Lioba Huelsboemer, Jake Moscarelli, Alna Dony, Alna Dony, Sam Boroumand, Alejandro Kochen, Leonard Knoedler, Leonard Knoedler, Catherine T. Yu, Sacha C. Hauc, Viola A. Stögner, Richard N. Formica, Christiane G. Lian, Georg F. Murphy, Bohdan Pomahac, Martin Kauke-Navarro   +15 more
doaj   +2 more sources

Re-Evaluating the Transplant Glomerulopathy Lesion—Beyond Donor-Specific Antibodies [PDF]

Transplant International
There have been significant advances in short-term outcomes in renal transplantation. However, longer-term graft survival has improved only minimally.
Arun Chutani, Daniel Guevara-Pineda, Gabriel B. Lerner, Madhav C. Menon   +3 more
doaj   +2 more sources

Early posttransplant rituximab use in kidney transplant recipients with preexisting donor-specific antibodies [PDF]

Renal Failure
The presence of pretransplant anti-human leukocyte antigen (HLA) donor-specific antibodies (DSAs) is still a significant barrier to successful kidney transplantation, as it increases the risk of rejection and graft failure. Rituximab (anti-CD20 antibody)
Junji Yamauchi, Katalin Fornadi, Divya Raghavan, Duha Jweehan, Suayp Oygen, Silviana Marineci, Ann Pole, Dharmendra Jain, Eszter Lazar-Molnar, Miklos Z. Molnar   +9 more
doaj   +2 more sources

Impact of Transient and Persistent Donor-Specific Antibodies in Lung Transplantation [PDF]

Transplant International
Lung transplantation (LuTx) is an established treatment for patients with end-stage lung diseases, however, outcomes are limited by acute and chronic rejection.
S. Auner, C. Hillebrand, P. M. Boehm, J. Boecker, D. Koren, S. Schwarz, Z. Kovacs, G. Murakoezy, G. Fischer, C. Aigner, K. Hoetzenecker, P. Jaksch, A. Benazzo   +12 more
doaj   +2 more sources

Is lysate-based human leukocyte antigen crossmatch a reliable method to contraindicate a transplant?

Indian Journal of Transplantation, 2023
The presence of preformed cytotoxic donor-specific antibodies (DSAs) has been associated with inferior allograft outcomes in the immediate posttransplant period.
Shruti Tapiawala, Suchita Jogale, Bharat V Shah, Anuradha Raman   +3 more
doaj   +1 more source

Highly Sensitized Patients Are Well Served by Receiving a Compatible Organ Offer Based on Acceptable Mismatches

Frontiers in Immunology, 2021
Highly sensitized kidney patients accrue on the transplant waiting list due to their broad immunization against non-self Human Leucocyte Antigens (HLA).
Sebastiaan Heidt, Geert W. Haasnoot, Marissa J. H. van der Linden-van Oevelen, Frans H. J. Claas   +3 more
doaj   +1 more source

Cellular Therapies in Solid Organ Allotransplantation: Promise and Pitfalls

Frontiers in Immunology, 2021
Donor specific transfusions have been the basis of tolerance inducing protocols since Peter Medawar showed that it was experimentally feasible in the 1950s.
Brian I. Shaw, Jeffrey R. Ord, Chloe Nobuhara, Xunrong Luo   +3 more
doaj   +1 more source

Early Posttransplant Blood Transfusion and Risk for Worse Graft Outcomes

Kidney International Reports, 2021
Introduction: Blood transfusion is a risk factor for allosensitization. Nevertheless, blood transfusion posttransplant remains a common practice. We evaluated the effect of posttransplant blood transfusion on graft outcomes.
Reem Daloul, Juarez R. Braga, Alejandro Diez, April Logan, Todd Pesavento   +4 more
doaj   +1 more source

Early Antibody-Mediated Kidney Transplant Rejection: A Successful Case Without Donor-Specific Anti-HLA Antibodies

Revista Portuguesa de Nefrologia e Hipertensão, 2023
The diagnosis of antibody-mediated rejection has become more common and represents a major cause of kidney graft loss. The ideal treatment remains unknown, with little evidence supporting the use of a specific therapy.
Rita M. Silva, Rita Leal, Maria G. Marques, Luís Rodrigues, Lídia Santos, Catarina Romãozinho, Arnaldo Figueiredo, Rui Alves   +7 more
doaj   +1 more source