Results 1 to 10 of about 2,312,760 (293)

Targeting CD38 in Antibody-Mediated Rejection [PDF]

Transplant International
Antibody-mediated rejection (AMR) remains a major challenge in clinical transplantation. Current therapies have yielded inconsistent outcomes, highlighting the need for innovative approaches.
Katharina A. Mayer, Klemens Budde, Matthias Diebold, Matthias Diebold, Philip F. Halloran, Georg A. Böhmig   +5 more
doaj   +4 more sources

Antibody-Mediated Rejection and Sponge Effect in a Redo Lung Transplant Recipient

Case Reports in Transplantation, 2021
Long-term survival after lung transplant remains severely limited by chronic lung allograft dysfunction. Antibody-mediated rejection of lung transplant allografts is usually caused by donor-specific antibodies (DSAs) directed toward donor human leukocyte
Ashwini Arjuna, Michael T. Olson, Sofya Tokman, Rajat Walia, Thalachallour Mohanakumar, A. Samad Hashimi, Michael A. Smith, Ross M. Bremner, Ashraf Omar   +8 more
doaj   +2 more sources

Successful treatment of acute antibody-mediated rejection of liver allograft with imlifidase: A case report

Transplantation Reports, 2023
Although the incidence of acute antibody mediated rejection in liver transplantation is low, the consequences of acute antibody mediated rejection can be devastating, often leading to severe fibrotic changes and early graft loss.
Michie A. Adjei, Steven A. Wisel, Noriko Ammerman, Ashley Vo, Maha Guindi, Kambiz Kosari, Georgios Voidonikolas, Tsuyoshi Todo, Nicholas N. Nissen, Stanley C. Jordan, Irene K. Kim   +10 more
doaj   +2 more sources

A systematic review of post-liver transplantation treatment and outcomes for late T-cell mediated, chronic ductopenic, and antibody-mediated rejection [PDF]

Hepatology Communications
Background:. Compared to the treatment for acute T-cell–mediated rejection, management of late T-cell–mediated rejection, chronic ductopenic rejection, and antibody-mediated rejection is more heterogeneous. Methods:.
Yianni Protopapadakis, Thomas D. Schiano, Helen S. Te, Anthony J. Demetris, Paul Y. Kwo, Dionisios Vrochides, Mark W. Russo   +6 more
doaj   +2 more sources

Biopsy-based Transcriptomics in Banff 2022 Antibody Mediated Rejection Categories [PDF]

Kidney International Reports
Introduction: Biopsy-based transcriptomics (BBT) supports antibody-mediated rejection (AMR) diagnostics, but Banff 2022 probable AMR and donor-specific antibodies (DSA)−/C4d−microvascular inflammation (MVI) remain unvalidated by BBT. Methods: We analyzed
Petra Hruba, Eva Girmanova, Dusan Harmacek, Marek Novotny, Vladimir Hanzal, Katerina Jaklova, Kerstin Hübel, Elena Rho, Kai Castrezana Lopez, Florian Westphal, Ariana Gaspert, Brigit Maria Helmchen, Seraina von Moos, Lukas Weidmann, Martin Kment, Ludek Voska, Thomas Schachtner, Ondrej Viklicky   +17 more
doaj   +2 more sources

Efficacy and safety of bortezomib in the treatment of active antibody-mediated rejection in adult kidney-transplant recipients: A single-center retrospective study

Indian Journal of Transplantation, 2022
Introduction: The management of active antibody-mediated rejection (ABMR) is evolving, and optimal treatment remains uncertain due to incomplete understanding of pathogenesis. Bortezomib is found to be useful in the treatment of active ABMR.
Dharmendra Bhadauria, Sai Kumar, Monika Yachha, Anupma Kaul, Manas Ranjan Patel, Ravi Shankar Kushwaha, Manas R Behera, Narayan Prasad   +7 more
doaj   +1 more source

Early Antibody-Mediated Kidney Transplant Rejection: A Successful Case Without Donor-Specific Anti-HLA Antibodies

Revista Portuguesa de Nefrologia e Hipertensão, 2023
The diagnosis of antibody-mediated rejection has become more common and represents a major cause of kidney graft loss. The ideal treatment remains unknown, with little evidence supporting the use of a specific therapy.
Rita M. Silva, Rita Leal, Maria G. Marques, Luís Rodrigues, Lídia Santos, Catarina Romãozinho, Arnaldo Figueiredo, Rui Alves   +7 more
doaj   +1 more source

Allograft rejection in kidney transplantation – A retrospective study of impact on graft and patient outcome

Indian Journal of Transplantation, 2022
Background: Renal allograft rejection is a major cause of graft dysfunction, and it is a predictor of long-term allograft loss. Advances in immunosuppression have decreased the influence of acute rejection on graft survival.
M P Shamsudheen, Abid Kuchay, Vijay Chander Gupta, Isha Tiwari, Raja Karthik, Uttara Das, Swarnalatha Guditi, Gangadhar Taduri   +7 more
doaj   +1 more source

Artemisinin Attenuates Transplant Rejection by Inhibiting Multiple Lymphocytes and Prolongs Cardiac Allograft Survival

Frontiers in Immunology, 2021
Immunological rejection is an important factor resulting in allograft dysfunction, and more valid therapeutic methods need to be explored to improve allograft outcomes.
Zhe Yang, Fei Han, Tao Liao, Haofeng Zheng, Zihuan Luo, Maolin Ma, Jiannan He, Lei Li, Yongrong Ye, Rui Zhang, Zhengyu Huang, Yannan Zhang, Qiquan Sun   +12 more
doaj   +1 more source

Blood group-specific apheresis in combination with daratumumab as a rescue therapy of acute antibody-mediated rejection in a case of ABO- and human leukocyte antigen-incompatible kidney transplantation

SAGE Open Medical Case Reports, 2023
We report a case of antibody-mediated rejection treated with the human CD38 monoclonal antibody daratumumab in a 58-year-old female patient with end-stage kidney disease due to autosomal dominant polycystic kidney disease who received an ABO- and human ...
Can C Süsal, Leonie Kraft, Andrea Ender, Caner Süsal, Amelie Schwenger, Kerstin Amann, Georg A Böhmig, Vedat Schwenger   +7 more
doaj   +1 more source