Results 31 to 40 of about 2,312,760 (293)
Endothelial cell antibody-mediated rejection and successful retransplantation in a heart transplanted patient [PDF]
, 2012 Antibody-mediated rejection (AMR) plays a significant role in cardiac allograft dysfunction, and recently a consensus regarding the diagnosis of AMR has been published.
Sigurdardottir, V +7 more
core +2 more sources
EBioMedicine, 2019 Background: Antibody-mediated rejection, a leading cause of renal allograft graft failure, is diagnosed by histological assessment of invasive allograft biopsies. Accurate non-invasive biomarkers are not available.
Elisabet Van Loon +16 more
doaj +1 more source
Balancing B cell responses to the allograft: implications for vaccination
Frontiers in Immunology, 2022 Balancing enough immunosuppression to prevent allograft rejection and yet maintaining an intact immune system to respond to vaccinations, eliminate invading pathogens or cancer cells is an ongoing challenge to transplant physicians.
Clarkson Crane +5 more
doaj +1 more source
IgE in Antibody-Mediated Rejection [PDF]
Clinical Journal of the American Society of Nephrology, 2020 It was nearly half a century ago that Colvin and Dvorak ([1][1]) identified infiltrating basophils and mast cells in kidney transplant rejection using simple light microscopy. They astutely recognized this finding to be “analogous to that reported in various delayed hypersensitivity processes ...
Benjamin A, Adam, Howard M, Gebel
openaire +2 more sources
Medicina, 2021 Kidney transplantation is the best treatment modality for end-stage kidney disease, leading to improvement in a patient’s quality and quantity of life.
Sambhavi Krishnamoorthy, Yousuf Kyeso
doaj +1 more source
Antibody-mediated rejection in hand transplantation [PDF]
Transplant International, 2013 Clinical relevance of antibody-mediated rejection (ABMR) in vascularized composite allotransplantation (VCA) has not been defined. We herein describe a novel type of donor-specific antibody (DSA) and B-cell-associated rejection in hand transplantation. In 2003, a bilateral forearm transplantation was performed on a 42-year-old male patient.
Annemarie, Weissenbacher +7 more
openaire +2 more sources
, 2022 This study investigates the burden of disease among kidney transplant recipients that have developed Chronic Active Antibody Mediated Rejection (caAMR) compared with kidney transplant recipients that have not developed ...
Anita Burrell
core +4 more sources
Case Reports in Transplantation, 2016 In renal transplantation, treatment options for antibody-mediated rejection are limited. Here, we report a case of severe AMR treated with eculizumab. A 50-year-old woman known for end stage kidney disease secondary to IgA nephropathy received a kidney ...
Duy Tran +5 more
doaj +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Antibody-mediated Rejection in Kidney Transplant: An Unmastered Area
Indian Journal of TransplantationAntibody-mediated rejection (ABMR) remains a significant cause of allograft failure in patients with kidney transplantation. Despite successful strategies to treat ABMR, irreversible injury in the form of transplant glomerulopathy commonly manifests ...
Shahul Valavoor +2 more
doaj +1 more source