Results 21 to 30 of about 2,312,760 (293)

IgE-Mediated Immune Response and Antibody-Mediated Rejection [PDF]

, 2020
Active antibody-mediated rejection is the main cause of kidney transplant loss, sharing with SLE the alloimmune response and the systemic activation of the IFN-α pathway.
Elena Ranieri, Rascio, Federica, Castellano, Giuseppe, Michela Seveso, Federica Rascio, Simone, Simona, Stallone, Giovanni, Elisabetta Manno, Cozzi, Emanuele, Netti, Giuseppe Stefano, Seveso, Michela, Ranieri, Elena, Grandaliano, Giuseppe, Paola Pontrelli, Simona Simone, Barbara Infante, Giuseppe Castellano, Giuseppe Stefano Netti, Loreto Gesualdo, Giovanni Stallone, Manno, Elisabetta, Emanuele Cozzi, Giuseppe Grandaliano, Gesualdo, Loreto, Pontrelli, Paola, Infante, Barbara   +25 more
core   +2 more sources

Antibody Mediated Rejection [PDF]

Clinical Journal of the American Society of Nephrology, 2006
It now is recognized that both acute and chronic allograft rejection may be mediated by alloantibodies. This constitutes a major shift in our thinking over the past 40 yr. We previously reviewed the articles that are relevant to the humoral theory: McKenna et al. (1), Terasaki (2), Cai and Terasaki (3), and Terasaki and Cai (4). Here we review articles
Paul, Terasaki, Kazuo, Mizutani
openaire   +2 more sources

Advances in Antibody Mediated Rejection [PDF]

, 2013
Kidney transplantation is considered the treatment of choice for patients with end-stage renal disease, and is associated with improved survival, better quality of life and reduced costs when compared with dialysis.[1, 2] However, the renal transplantation waiting list is forever growing, out of proportion to the number of donors.[2, 3] Therefore it is
Sharma, Siddharth, Oliver, Kimberley, Mudge, David W.   +2 more
openaire   +3 more sources

Issues in solid-organ transplantation in children: translational research from bench to bedside

Clinics, 2014
In this review, we identify important challenges facing physicians responsible for renal and cardiac transplantation in children based on a review of the contemporary medical literature. Regarding pediatric renal transplantation, we discuss the challenge
Steven E. Lipshultz, Jayanthi J. Chandar, Paolo G. Rusconi, Alessia Fornoni, Carolyn L. Abitbol, George W. Burke III, Gaston E. Zilleruelo, Si M. Pham, Elena E. Perez, Ruchika Karnik, Juanita A. Hunter, Danielle D. Dauphin, James D. Wilkinson   +12 more
doaj   +1 more source

Behaviour of non-donor specific antibodies during rapid re-synthesis of donor specific HLA antibodies after antibody incompatible renal transplantation [PDF]

, 2013
Background: HLA directed antibodies play an important role in acute and chronic allograft rejection. During viral infection of a patient with HLA antibodies, the HLA antibody levels may rise even though there is no new immunization with antigen ...
Rizwan Hamer, Imray, C. (Chris), Nithya S Krishnan, Lam Chin Tan, Higgins Robert M., Daga Sunil, Lowe, David Philip, David Briggs, Zehnder Daniel, Tan Lam Chin, Zehnder, Daniel, Robert M Higgins, Daniel Zehnder, Kashi Habib, Dave Lowe, Christopher Imray, Sunil Daga, Neil Raymond, Krishnan, Nithya S., Lam, F. T., Higgins, Rob, Lam F. T., Habib Kashi, Daga, Sunil, F T Lam, Krishnan Nithya S., Lowe Dave, Hamer, Rizwan, Briggs David, Kashi, Habib, Briggs, David, Dr., Raymond Neil, Raymond, Neil T., Hamer Rizwan, Tan, Lam Chin, Imray Christopher   +35 more
core   +1 more source

Sugar and spice: Fc glycosylation in antibody-mediated transplant rejection [PDF]

, 2022
Bharadwaj et al.(1) demonstrate that anti-donor HLA antibodies display low levels of Fc fucosylation. This signature was associated with potent provocation of NK cell effector functions and was discriminative for active antibody-mediated rejection among ...
Valenzuela, Nicole M., Valenzuela, Nicole M,, Valenzuela, Nicole M   +2 more
core   +1 more source

Use of TandemHeart as Bridge to Recovery for Antibody-Mediated Rejection in a Heart Transplant Patient

JACC: Case Reports, 2020
Antibody-mediated rejection is a major cause of graft failure, mortality, and morbidity among cardiac transplant recipients. We present the first reported case of TandemHeart (LivaNova, Pittsburgh, Pennsylvania) used in the management of antibody ...
Juan P. Rodriguez-Escudero, MD, Antonio Duran, MD, Clement Eiswirth, MD, Stacy A. Mandras, MD, Sapna V. Desai, MD, Hamang M. Patel, MD, Rajan Patel, MD, Hector O. Ventura, MD, Selim R. Krim, MD   +8 more
doaj   +1 more source

Antibody-Mediated Rejection of a Pancreas Allograft [PDF]

American Journal of Transplantation, 2006
The role of antibody-mediated rejection (AMR) in pancreas transplantation is poorly understood. Here, we report on a patient who developed AMR of his pancreas allograft after receiving a simultaneous pancreas-kidney transplant. Pre-operative enhanced cytotoxicity and flow cytometry T-cell crossmatches were negative; B-cell crossmatches were not ...
M L, Melcher, J L, Olson, L A, Baxter-Lowe, P G, Stock, A M, Posselt   +4 more
openaire   +2 more sources

Prevalence of the Quilty effect in endomyocardial biopsy of patients after heart transplantation – from cellular rejection to antibody-mediated rejection? [PDF]

, 2016
The significance of the Quilty effect (QE) is not fully understood. It was once proposed to be related to acute cellular rejection (ACR). We aim to assess the relation between QE prevalence and antibody-mediated rejection (AMR).
Sylwia Szymanska, Wieslawa Grajkowska, Maciej Pronicki, Malgorzata Sobieszczanska-Malek, Michal Pyzlak, Tomasz Zielinski   +5 more
core   +1 more source

Antibody-Mediated Rejection in Lung Transplantation [PDF]

Current Transplantation Reports, 2015
There has been increasing awareness of antibody-mediated rejection (AMR) as an important cause of graft failure after lung transplantation in recent years. However, the diagnostic criteria for pulmonary AMR are not well defined. All four tenets of AMR in kidney and heart transplantation, graft dysfunction, complement component deposition, circulating ...
Hrishikesh S, Kulkarni, Bradford C, Bemiss, Ramsey R, Hachem   +2 more
openaire   +2 more sources