Results 1 to 10 of about 2,253,953 (246)

Antibody-Mediated Rejection of Solid-Organ Allografts [PDF]

New England Journal of Medicine, 2018
To the editor: the comprehensive review article by Loupy and Lefaucheur (Sept. 20 issue)1 on antibody-mediated rejection describes major advances in understanding the pathophysiological process and diagnosis of antibody-mediated rejection, but successful treatment is still limited to the acute forms of antibody-mediated rejection.2 Allograft loss ...
Gary Curhan, Alexandre Loupy
exaly   +9 more sources

Antibody-Mediated Rejection and Sponge Effect in a Redo Lung Transplant Recipient

Case Reports in Transplantation, 2021
Long-term survival after lung transplant remains severely limited by chronic lung allograft dysfunction. Antibody-mediated rejection of lung transplant allografts is usually caused by donor-specific antibodies (DSAs) directed toward donor human leukocyte
Ashwini Arjuna, Michael T. Olson, Sofya Tokman, Rajat Walia, Thalachallour Mohanakumar, A. Samad Hashimi, Michael A. Smith, Ross M. Bremner, Ashraf Omar   +8 more
doaj   +2 more sources

Successful treatment of acute antibody-mediated rejection of liver allograft with imlifidase: A case report

Transplantation Reports, 2023
Although the incidence of acute antibody mediated rejection in liver transplantation is low, the consequences of acute antibody mediated rejection can be devastating, often leading to severe fibrotic changes and early graft loss.
Michie A. Adjei, Steven A. Wisel, Noriko Ammerman, Ashley Vo, Maha Guindi, Kambiz Kosari, Georgios Voidonikolas, Tsuyoshi Todo, Nicholas N. Nissen, Stanley C. Jordan, Irene K. Kim   +10 more
doaj   +2 more sources

Targeting CD38 in Antibody-Mediated Rejection

Transplant International
Antibody-mediated rejection (AMR) remains a major challenge in clinical transplantation. Current therapies have yielded inconsistent outcomes, highlighting the need for innovative approaches.
Katharina A. Mayer, Klemens Budde, Matthias Diebold, Matthias Diebold, Philip F. Halloran, Georg A. Böhmig   +5 more
doaj   +3 more sources

Editorial: Antibody-mediated rejection

Frontiers in Transplantation
Ramsey R. Hachem, Thalachallour Mohanakumar   +1 more
doaj   +3 more sources

Efficacy and safety of bortezomib in the treatment of active antibody-mediated rejection in adult kidney-transplant recipients: A single-center retrospective study

Indian Journal of Transplantation, 2022
Introduction: The management of active antibody-mediated rejection (ABMR) is evolving, and optimal treatment remains uncertain due to incomplete understanding of pathogenesis. Bortezomib is found to be useful in the treatment of active ABMR.
Dharmendra Bhadauria, Sai Kumar, Monika Yachha, Anupma Kaul, Manas Ranjan Patel, Ravi Shankar Kushwaha, Manas R Behera, Narayan Prasad   +7 more
doaj   +1 more source

Early Antibody-Mediated Kidney Transplant Rejection: A Successful Case Without Donor-Specific Anti-HLA Antibodies

Revista Portuguesa de Nefrologia e Hipertensão, 2023
The diagnosis of antibody-mediated rejection has become more common and represents a major cause of kidney graft loss. The ideal treatment remains unknown, with little evidence supporting the use of a specific therapy.
Rita M. Silva, Rita Leal, Maria G. Marques, Luís Rodrigues, Lídia Santos, Catarina Romãozinho, Arnaldo Figueiredo, Rui Alves   +7 more
doaj   +1 more source

Allograft rejection in kidney transplantation – A retrospective study of impact on graft and patient outcome

Indian Journal of Transplantation, 2022
Background: Renal allograft rejection is a major cause of graft dysfunction, and it is a predictor of long-term allograft loss. Advances in immunosuppression have decreased the influence of acute rejection on graft survival.
M P Shamsudheen, Abid Kuchay, Vijay Chander Gupta, Isha Tiwari, Raja Karthik, Uttara Das, Swarnalatha Guditi, Gangadhar Taduri   +7 more
doaj   +1 more source

Antibody Mediated Rejection [PDF]

Clinical Journal of the American Society of Nephrology, 2006
It now is recognized that both acute and chronic allograft rejection may be mediated by alloantibodies. This constitutes a major shift in our thinking over the past 40 yr. We previously reviewed the articles that are relevant to the humoral theory: McKenna et al. (1), Terasaki (2), Cai and Terasaki (3), and Terasaki and Cai (4). Here we review articles
Paul, Terasaki, Kazuo, Mizutani
openaire   +2 more sources

Artemisinin Attenuates Transplant Rejection by Inhibiting Multiple Lymphocytes and Prolongs Cardiac Allograft Survival

Frontiers in Immunology, 2021
Immunological rejection is an important factor resulting in allograft dysfunction, and more valid therapeutic methods need to be explored to improve allograft outcomes.
Zhe Yang, Fei Han, Tao Liao, Haofeng Zheng, Zihuan Luo, Maolin Ma, Jiannan He, Lei Li, Yongrong Ye, Rui Zhang, Zhengyu Huang, Yannan Zhang, Qiquan Sun   +12 more
doaj   +1 more source