Results 21 to 30 of about 2,253,953 (246)

Behaviour of non-donor specific antibodies during rapid re-synthesis of donor specific HLA antibodies after antibody incompatible renal transplantation [PDF]

open access: yes, 2013
Background: HLA directed antibodies play an important role in acute and chronic allograft rejection. During viral infection of a patient with HLA antibodies, the HLA antibody levels may rise even though there is no new immunization with antigen ...
Rizwan Hamer   +35 more
core   +1 more source

Sugar and spice: Fc glycosylation in antibody-mediated transplant rejection [PDF]

open access: yes, 2022
Bharadwaj et al.(1) demonstrate that anti-donor HLA antibodies display low levels of Fc fucosylation. This signature was associated with potent provocation of NK cell effector functions and was discriminative for active antibody-mediated rejection among ...
Valenzuela, Nicole M.   +2 more
core   +1 more source

Use of TandemHeart as Bridge to Recovery for Antibody-Mediated Rejection in a Heart Transplant Patient

open access: yesJACC: Case Reports, 2020
Antibody-mediated rejection is a major cause of graft failure, mortality, and morbidity among cardiac transplant recipients. We present the first reported case of TandemHeart (LivaNova, Pittsburgh, Pennsylvania) used in the management of antibody ...
Juan P. Rodriguez-Escudero, MD   +8 more
doaj   +1 more source

Antibody-Mediated Rejection of a Pancreas Allograft [PDF]

open access: yesAmerican Journal of Transplantation, 2006
The role of antibody-mediated rejection (AMR) in pancreas transplantation is poorly understood. Here, we report on a patient who developed AMR of his pancreas allograft after receiving a simultaneous pancreas-kidney transplant. Pre-operative enhanced cytotoxicity and flow cytometry T-cell crossmatches were negative; B-cell crossmatches were not ...
M L, Melcher   +4 more
openaire   +2 more sources

Prevalence of the Quilty effect in endomyocardial biopsy of patients after heart transplantation – from cellular rejection to antibody-mediated rejection? [PDF]

open access: yes, 2016
The significance of the Quilty effect (QE) is not fully understood. It was once proposed to be related to acute cellular rejection (ACR). We aim to assess the relation between QE prevalence and antibody-mediated rejection (AMR).
Sylwia Szymanska   +5 more
core   +1 more source

Endothelial cell antibody-mediated rejection and successful retransplantation in a heart transplanted patient [PDF]

open access: yes, 2012
Antibody-mediated rejection (AMR) plays a significant role in cardiac allograft dysfunction, and recently a consensus regarding the diagnosis of AMR has been published.
Sigurdardottir, V   +7 more
core   +2 more sources

Development and validation of a peripheral blood mRNA assay for the assessment of antibody-mediated kidney allograft rejection: A multicentre, prospective studyResearch in context

open access: yesEBioMedicine, 2019
Background: Antibody-mediated rejection, a leading cause of renal allograft graft failure, is diagnosed by histological assessment of invasive allograft biopsies. Accurate non-invasive biomarkers are not available.
Elisabet Van Loon   +16 more
doaj   +1 more source

Antibody-mediated rejection in hand transplantation [PDF]

open access: yesTransplant International, 2013
Clinical relevance of antibody-mediated rejection (ABMR) in vascularized composite allotransplantation (VCA) has not been defined. We herein describe a novel type of donor-specific antibody (DSA) and B-cell-associated rejection in hand transplantation. In 2003, a bilateral forearm transplantation was performed on a 42-year-old male patient.
Annemarie, Weissenbacher   +7 more
openaire   +2 more sources

Balancing B cell responses to the allograft: implications for vaccination

open access: yesFrontiers in Immunology, 2022
Balancing enough immunosuppression to prevent allograft rejection and yet maintaining an intact immune system to respond to vaccinations, eliminate invading pathogens or cancer cells is an ongoing challenge to transplant physicians.
Clarkson Crane   +5 more
doaj   +1 more source

A systematic review of post-liver transplantation treatment and outcomes for late T-cell mediated, chronic ductopenic, and antibody-mediated rejection

open access: yesHepatology Communications
Background:. Compared to the treatment for acute T-cell–mediated rejection, management of late T-cell–mediated rejection, chronic ductopenic rejection, and antibody-mediated rejection is more heterogeneous. Methods:.
Yianni Protopapadakis   +6 more
doaj   +1 more source

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