Results 31 to 40 of about 2,253,953 (246)
Medicina, 2021 Kidney transplantation is the best treatment modality for end-stage kidney disease, leading to improvement in a patient’s quality and quantity of life.
Sambhavi Krishnamoorthy, Yousuf Kyeso
doaj +1 more source
Antibody-Mediated Rejection in Lung Transplantation [PDF]
Current Transplantation Reports, 2015 There has been increasing awareness of antibody-mediated rejection (AMR) as an important cause of graft failure after lung transplantation in recent years. However, the diagnostic criteria for pulmonary AMR are not well defined. All four tenets of AMR in kidney and heart transplantation, graft dysfunction, complement component deposition, circulating ...
Hrishikesh S, Kulkarni +2 more
openaire +2 more sources
IgE in Antibody-Mediated Rejection [PDF]
Clinical Journal of the American Society of Nephrology, 2020 It was nearly half a century ago that Colvin and Dvorak ([1][1]) identified infiltrating basophils and mast cells in kidney transplant rejection using simple light microscopy. They astutely recognized this finding to be “analogous to that reported in various delayed hypersensitivity processes ...
Benjamin A, Adam, Howard M, Gebel
openaire +2 more sources
, 2022 This study investigates the burden of disease among kidney transplant recipients that have developed Chronic Active Antibody Mediated Rejection (caAMR) compared with kidney transplant recipients that have not developed ...
Anita Burrell
core +4 more sources
Case Reports in Transplantation, 2016 In renal transplantation, treatment options for antibody-mediated rejection are limited. Here, we report a case of severe AMR treated with eculizumab. A 50-year-old woman known for end stage kidney disease secondary to IgA nephropathy received a kidney ...
Duy Tran +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao +23 more
wiley +1 more source
Antibody-mediated Rejection in Kidney Transplant: An Unmastered Area
Indian Journal of TransplantationAntibody-mediated rejection (ABMR) remains a significant cause of allograft failure in patients with kidney transplantation. Despite successful strategies to treat ABMR, irreversible injury in the form of transplant glomerulopathy commonly manifests ...
Shahul Valavoor +2 more
doaj +1 more source
KTeXpand – a novel microfluidic device for advanced cell based cross matching
Current Directions in Biomedical Engineering, 2022 Antibody-mediated rejection after kidney transplantation is a major limitation for long-term survival of donated kidneys within the recipient allograft.
Schneider Daniel +8 more
doaj +1 more source
Angiotensin II type 1 receptor antibody-mediated kidney rejection unresponsive to treatment
, 2023 Allograft rejection is a significant cause of renal transplant failure which needs prompt diagnosis and treatment for graft salvage. Angiotensin II type 1 receptor antibody-mediated rejection (AT1R-AMR) is increasingly being identified as the etiology of
Sally Campbell-Lee (10638875) +5 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source