Results 51 to 60 of about 2,312,760 (293)

Cloning and expression of porcine β1,4 N-acetylgalactosaminyl transferase encoding a new xenoreactive antigen [PDF]

, 2014
Xenograft rejection of pigs organs with an engineered mutation in the GGTA-1 gene (GTKO) remains a predominantly antibody mediated process which is directed to a variety of non-Gal protein and carbohydrate antigens.
Kogelberg, H, Du, Z, Stalboerger, P, Byrne, GW, McGregor, CG   +4 more
core  

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source

Acute Antibody-mediated Rejection Coexisting With T Cell–mediated Rejection in Pediatric ABO-incompatible Transplantation

Transplantation Direct, 2022
Background. The management and outcome of ABO-incompatible (ABO-I) liver transplantation (LT) has been improving over the past few decades. Recently, the introduction of a pathological evaluation of acute antibody-mediated rejection (AMR) for liver ...
Yusuke Yanagi, MD, PhD, Seisuke Sakamoto, MD, PhD, Masaki Yamada, MD, PhD, Koutaro Mimori, MD, Toshimasa Nakao, MD, PhD, Tasuku Kodama, MD, PhD, Hajime Uchida, MD, PhD, Seiichi Shimizu, MD, PhD, Akinari Fukuda, MD, PhD, Noriyuki Nakano, MD, PhD, Chiduko Haga, MD, PhD, Takako Yoshioka, MD, PhD, Mureo Kasahara, MD, PhD   +12 more
doaj   +1 more source

Risk factors for the development of acute antibody mediated rejection.

, 2015
ABOi, ABO incompatible; HLAs, sensitized to HLA; KT, kidney transplantation; PRA, panel reactive antibody; LURD, living unrelated donor; RTX, rituximab, HLA-DSA; donor-specific anti-HLA antibodyRisk factors for the development of acute antibody mediated ...
Eun-Jee Oh (727761), In Sung Moon (401194), Hyung Duk Kim (727760), Ji-Il Kim (401193), Yu Young Joo (727758), Byung Ha Chung (314449), Jaesin Lee (727759), Chul Woo Yang (277266), Bum Soon Choi (314460), Cheol Whee Park (314462), Yong-Soo Kim (42082)   +10 more
core   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Report from a consensus conference on antibody-mediated rejection in heart transplantation

, 2011
The problem of AMR remains unsolved because standardized schemes for diagnosis and treatment remains contentious. Therefore, a consensus conference was organized to discuss the current status of antibody-mediated rejection (AMR) in heart ...
E. Rene Rodriguez, Kobashigawa, Jon, Naveen Pereira, Gerald Berry, Lori West, Jeffrey L. Platt, Elaine F. Reed, Mohacsi, Paul, Reinsmoen, Nancy, Maria G. Crespo-Leiro, Kfoury, Abdallah G, Consensus Conference Participants,, Abdallah G. Kfoury, Crespo-Leiro, Maria G, Adrian Van Bakel, Annalisa Angelini, Zeevi, Adriana, Taylor, David O, David O. Taylor, Suciu-Foca, Nicole, Starling, Randy, Stephan M. Ensminger, Adriana Zeevi, Reichenspurner, Hermann, Stuart D. Russell, Lawrence Czer, Nicola Hiemann, Pereira, Naveen, Patel, Jignesh, Nancy Reinsmoen, Hiemann, Nicola, Mancini, Donna, Randy Starling, Czer, Lawrence, Margaret Burke, Rose, Marlene L, Nicole Suciu-Foca, Tallaj, Jose, Jose Tallaj, Jignesh Patel, Platt, Jeffrey L, Hermann Reichenspurner, Reed, Elaine F, Angelini, Annalisa, Rodriguez, E Rene, Zuckermann, Andreas, Berry, Gerald, Van Bakel, Adrian, Jon Kobashigawa, Donna Mancini, Ensminger, Stephan M, Russell, Stuart D, Andreas Zuckermann, West, Lori, Paul Mohacsi, Marlene L. Rose, Burke, Margaret, REINSMOEN N, ENSMINGER SM, REED EF, Taylor, David O., PATEL J, Platt, Jeffrey L., Reed, Elaine F., RODRIGUEZ ER, TALLAJ J, RUSSELL SD, MOHACSI P, REICHENSPURNER H, Rose, Marlene L., CONSENSUS CONFERENCE PARTICIPANTS, ZEEVI A, ROSE ML, Ensminger, Stephan M., CRESPO LEIRO MG, PEREIRA N, HIEMANN N, Crespo-Leiro, Maria G., Kfoury, Abdallah G., PLATT JL, VAN BAKEL A, MANCINI D, KFOURY AG, BERRY G, Rodriguez, E. Rene, BURKE M, Crespo Leiro, Marisa, STARLING R, TAYLOR DO, SUCIU FOCA N, WEST L, ZUCKERMANN A, Russell, Stuart D., CZER L, KOBASHIGAWA J   +94 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

IVIG Associated Aseptic Meningitis in a Renal Transplant Patient

Case Reports in Transplantation, 2017
The management of antibody-mediated rejection in renal transplant recipients involves plasmapheresis with IVIG. Aseptic meningitis is a rare adverse effect of IVIG therapy and is a diagnosis of exclusion.
Tamara Wanigasekera, Rachel J. Grainger, Donal J. Sexton, Colm Magee   +3 more
doaj   +1 more source

Repeated cycles of high-dose intravenous immunoglobulin and plasmapheresis for treatment of late antibody-mediated rejection of renal transplants

, 2017
Background/purpose: Intravenous immunoglobulin (IVIG) plays a central role in the treatment of antibody-mediated rejection (AMR) of renal allografts, but the treatment outcomes for late AMR (> 6 months after transplantation) are poor.
吳明修;李志元;林維洲;葉啟娟;楊卿堯;蔡孟昆, Lee, Chih-Yuan;Lin, Wei-Chou;Wu, Ming-Shiou;Yang, Ching-Yao;Yeh, Chi-Chuan;Tsai, Meng-Kun   +1 more
core   +1 more source

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

Advanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai, Pengchong Du, Zhaoyang Wang, Surilige, Rangga Fokta, Renjian Tan, Xiqing Zhao, Shuoyi Zhang, Yuecheng Wang, Yixin Zhang, Ziliang Fu, Rui Gong, Cheng Jiang, Yisheng He, Qiguang Wang, Renke Li, Khoon Lim, Junnan Tang, Xiaolin Cui   +18 more
wiley   +1 more source