Results 61 to 70 of about 2,312,760 (293)

MetaboSense: An Integrated Quantum Dot‐Mediated Aptamer Assay and Modular Microfluidic Platform for Continuous In‐Line Monitoring of Lung Metabolism During Ex Vivo Perfusion

Advanced Science, EarlyView.
MetaboSense is a first‐of‐its‐kind microfluidic platform enabling continuous, in‐line monitoring of glucose and lactate during ex vivo lung perfusion. Combining a quantum dot–mediated aptamer assay with mixing, depletion, and optofluidic detection modules, it achieves 60–s temporal resolution and shows strong agreement with standard blood gas analyzers,
Sanjana Srikant, Pouyan Keshavarz Motamed, Thomas Borrillo, Lielle Ronen, Gabriel Siebiger, Guillermo Garza, Hesam Abouali, Md Fahim Al Fattah, Ines Jaber, Dayan Ban, Marcelo Cypel, Mingyao Liu, Shaf Keshavjee, Andrew T. Sage, Mahla Poudineh   +14 more
wiley   +1 more source

Root‐Inspired Microneedle Patch With Interlocked Rigid‐Soft Architecture for High Tissue‐Adaptiveness

Advanced Science, EarlyView.
A root‐inspired microneedle array patch uses lattice‐based mechanical interlocking to unite rigid microneedles with a flexible substrate. The interlocked rigid–soft architecture improves interfacial bonding, supports stable adhesion on curved and wet tissues under dynamic motion, and provides a versatile platform for robust biointerfacing and future ...
Jongchan Lee, Yeongjun Song, Yonghyun Cho, Hyo In Kim, Dong‐Hyun Youn, Jinbong Park, Seungbeom Choi, Dohyun Kwon, Brian Jun Lee, Sangyul Baik   +9 more
wiley   +1 more source

Combined Heart and Kidney Transplantation: Clinical Experience in 100 Consecutive Patients

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Combined heart and kidney transplantation (HKTx) is performed in patients with severe heart failure and advanced renal insufficiency. We analyzed the long‐term survival after HKTx, the influence of age and dialysis status, the rates of cardiac
Morcos Atef Awad, Lawrence S. C. Czer, Dominic Emerson, Stanley Jordan, Michele A. De Robertis, James Mirocha, Evan Kransdorf, David H. Chang, Jignesh Patel, Michelle Kittleson, Danny Ramzy, Joshua S. Chung, J. Louis Cohen, Fardad Esmailian, Alfredo Trento, Jon A. Kobashigawa   +15 more
doaj   +1 more source

Animals treated with post-transplant APRIL/BLyS blockade did not develop antibody mediated rejection.

, 2019
Animals treated with post-transplant APRIL/BLyS blockade did not develop antibody mediated rejection.
Natalie M. Bath (6316517), Arjang Djamali (6316535), Brittney A. Boldt (6316523), Sarah E. Panzer (6316532), Robert R. Redfield III (6316538), Xiang Ding (607469), Adarsh Sukhwal (6316526), Shannon R. Reese (6316529), Nancy A. Wilson (36137), Bret M. Verhoven (6316520)   +9 more
core   +1 more source

Histopathologic insights into the mechanism of anti-non-Gal antibody-mediated pig cardiac xenograft rejection. [PDF]

, 2013
The histopathology of cardiac xenograft rejection has evolved over the last 20 yr with the development of new modalities for limiting antibody-mediated injury, advancing regimens for immune suppression, and an ever-widening variety of new donor genetics.
Tazelaar, HD, Cooper, DK, Burcin Ekser, Byrne, GW, Guerard W. Byrne, Simon C. Robson, Azimzadeh, AM, David K. C. Cooper, Pierson, RN, McGregor, CG, Christopher G. A. McGregor, Robson, SC, Richard N. Pierson, Agnes M. Azimzadeh, Mohamed Ezzelarab, Ekser, B, Ezzelarab, M, Henry D. Tazelaar   +17 more
core   +1 more source

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

The Importance of C4d in Biopsies of Kidney Transplant Recipients

Clinical and Developmental Immunology, 2013
Antibody-mediated rejection (AMR) is highly detrimental to the prolonged survival of transplanted kidneys. C4d has been regarded as a footprint of AMR tissue damage, and the introduction of C4d staining in daily clinical practice aroused an ever ...
Rosana Rosa Miranda Corrêa, Juliana Reis Machado, Marcos Vinícius da Silva, Fernanda Rodrigues Helmo, Camila Souza Oliveira Guimarães, Laura Penna Rocha, Ana Carolina Guimarães Faleiros, Marlene Antônia dos Reis   +7 more
doaj   +1 more source

Antibody-mediated lung transplant rejection [PDF]

Current Respiratory Care Reports, 2012
Antibody-mediated rejection after lung transplantation remains enigmatic. However, emerging evidence over the past several years suggests that humoral immunity plays an important role in allograft rejection. Indeed, the development of donor-specific antibodies after transplantation has been identified as an independent risk factor for acute cellular ...
openaire   +2 more sources

Clinical Significances of Anti-Collagen Type I and Type III Antibodies in Antibody-Mediated Rejection

, 2022
It is important to determine the clinical significance of non-human leukocyte antigen (HLA) antibodies and their association with antibody-mediated rejection (ABMR) of kidney allografts.
Park, Sehoon, Jeong, Chang Wook, Kim, Yon Su, Kim, Dong Ki, Song, Eun Young, Moon, Kyung Chul, Yang, Seung-Hee, Yang, Jaeseok, Kim, Jiyeon, Bhoo, Seong Hee, Ha, Jongwon, Oh, Kook-Hwan, Kim, Yong Chul, Lee, Hajeong, Cho, Semin, Joo, Kwon Wook, Min, Sang-Il   +16 more
core   +1 more source

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source