Results 71 to 80 of about 2,312,760 (293)

Quilty Lesions in the Endomyocardial Biopsies after Heart Transplantation [PDF]

open access: yesJournal of Pathology and Translational Medicine, 2019
Background The aim of this study was to investigate the clinical significance of Quilty lesions in endomyocardial biopsies (EMBs) of cardiac transplantation patients.
Haeyon Cho   +3 more
doaj   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

open access: yesAdvanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang   +10 more
wiley   +1 more source

Pathological diagnosis of antibody-mediated rejection in renal allograft without c4d staining, how much reliable?

open access: yesAdvanced Biomedical Research, 2012
Background: C4d as a part of complement activation process is a marker for detecting antibody-mediated rejection (ABMR) and its positivity accompanied by positive donor specific antibody (DSA), and morphologic view of humoral rejection has been suggested
Diana Taheri   +8 more
doaj   +1 more source

Ratio of antibody-mediated rejection according to complement binding activity.

open access: yes, 2018
Complement binding activity of dnDSA enhanced the incidence of AMR (P < 0.001, Chi-square for trend). The comparison of each group was based on Fisher`s exact test.
Eun-Jee Oh (727761)   +7 more
core   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

open access: yesAdvanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert   +8 more
wiley   +1 more source

CD38-targeted therapy with Daratumumab in clinical lung transplantation: A single-center experience

open access: yesJHLT Open
Background: Antibody-mediated rejection remains a major threat to long-term graft function after lung transplantation. Current therapies aim to eliminate circulating antibodies and suppress B-cell-activity but often fail to reduce donor-specific ...
Caroline Hillebrand   +14 more
doaj   +1 more source

The Involvement of Fcr Mechanisms in Antibody-Mediated Rejection

open access: yes, 2011
BACKGROUND: Antibody-mediated rejection is characterized by macrophage margination against vascular endothelium. The potential interactions triggered by antibodies between endothelial cells (EC) and macrophages have not been examined thoroughly in ...
李志元, LEE, CHIH-YUAN
core  

Acute antibody-mediated rejection of renal transplant associated with cellular crescents: First case report

open access: yes, 2011
Acute antibody-mediated rejection is characterized by histological abnormalities such as glomerulitis, capillaritis, or thrombosis associated with presence of C4d and specific anti-donor antibodies.
Viero, Rosa Marlene   +8 more
core   +1 more source

Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cell (MSC)‐based cell‐drug conjugates are constructed by anchoring rosiglitazone‐loaded nanoparticles onto the MSC surface. Sustained rosiglitazone release enhances MSC proliferation and paracrine activity while promoting anti‐inflammatory macrophage polarization.
Tenghui Ye   +6 more
wiley   +1 more source

The role of C4d and donor specific antibodies in face and hand transplantation—a systematic review

open access: yesFrontiers in Transplantation
To date, little is known about the mechanisms of rejection in vascularized composite allotransplantation, particularly for antibody mediated rejection.
Lioba Huelsboemer   +15 more
doaj   +1 more source

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