Results 11 to 20 of about 8,474,282 (288)

Behaviour of non-donor specific antibodies during rapid re-synthesis of donor specific HLA antibodies after antibody incompatible renal transplantation. [PDF]

PLoS ONE, 2013
BackgroundHLA directed antibodies play an important role in acute and chronic allograft rejection. During viral infection of a patient with HLA antibodies, the HLA antibody levels may rise even though there is no new immunization with antigen. However it
Nithya S Krishnan, Daniel Zehnder, Sunil Daga, Dave Lowe, F T Lam, Habib Kashi, Lam Chin Tan, Christopher Imray, Rizwan Hamer, David Briggs, Neil Raymond, Robert M Higgins   +11 more
doaj   +6 more sources

The impact of pretransplant donor-specific antibodies on graft outcome in renal transplantation: a six-year follow-up study

Clinics, 2012
OBJECTIVE: The significance of pretransplant, donor-specific antibodies on long-term patient outcomes is a subject of debate. This study evaluated the impact and the presence or absence of donor-specific antibodies after kidney transplantation on short ...
Elias David-Neto, Patricia Soares Souza, Nicolas Panajotopoulos, Helcio Rodrigues, Carlucci Gualberto Ventura, Daisa Silva Ribeiro David, Francine Brambate Carvalhinho Lemos, Fabiana Agena, William Carlos Nahas, Jorge Elias Kalil, Maria Cristina Ribeiro Castro   +10 more
doaj   +2 more sources

The Presence of Donor-Specific Antibodies in Renal Transplantation

Transplantation Proceedings, 2012
Determining the presence of anti-HLA antibodies before transplantation is an important factor to prevent loss of function among renal transplantations. In addition, recent studies have shown that not only the pretransplantation existence of anti-HLA antibody but also posttransplantation donor-specific antibodies (DSA) and non-donor-specific antibodies ...
Kilicarslan-Ayna, T., TOZKIR, HİLMİ, Sezer, A., GÜRKAN, HAKAN, Sari, G., SAĞIROĞLU, GÖNÜL, Copuroglu, E., Tan, S., Sagiroglu, T.   +8 more
openaire   +5 more sources

Successful Desensitization in a Patient with Donor-Specific Antibodies Persisting after Pretransplant Immunosuppression Using Intravenous Immunoglobulin and Plasma Exchange

Indian Journal of Transplantation
The use of posttransplant cyclophosphamide has revolutionized the field of haploidentical hematopoietic stem cell transplant. The impact has been especially enhanced in low- and middle-income countries. Unrelated donor pool in developing nations is often
Rohit Kapoor, Prashant Pandey, Amit Pande, Nivedita Dhingra, Lovy Gaur, Sugam Garg, Akriti Khare, Esha Kaul   +7 more
doaj   +2 more sources

An adjustable predictive score of graft survival in kidney transplant patients and the levels of risk linked to de novo donor-specific anti-HLA antibodies. [PDF]

PLoS ONE, 2017
Most predictive models and scores of graft survival in renal transplantation include factors known before transplant or at the end of the first year. They cannot be updated thereafter, even in patients developing donor-specific anti-HLA antibodies and ...
Aurélie Prémaud, Matthieu Filloux, Philippe Gatault, Antoine Thierry, Matthias Büchler, Eliza Munteanu, Pierre Marquet, Marie Essig, Annick Rousseau   +8 more
doaj   +2 more sources

Clinical relevance of circulating donor-specific HLA antibodies

Current Opinion in Organ Transplantation, 2010
For a long period of time complement-dependent cytotoxicity was the standard assay to demonstrate clinically relevant HLA antibodies in the serum of patients before transplantation. The introduction of more sensitive solid-phase assays to detect HLA antibodies had led to a lot of discussion on the clinical relevance of the presence of these antibodies ...
Claas, F.H.J., Frans HJ Claas
openaire   +4 more sources

Kidney transplant monitoring by anti donor specific antibodies

Transplant International, 1992
Donor-specific anti-HLA antibodies were studied by cytotoxicity crossmatching (CTXM) and flow cytometry crossmatching (FCXM) in 117 kidney transplant candidates; the same study was carried out in 33 cadaver-donor kidney recipients, during the first 3 post-transplant months, for which donor cells were available. Pre-transport evaluation showed that 82.9%
N Torlone, A Piazza, M Valeri, PI Monaco, L Provenzani, E Poggi, D Adorno, CU Casciani   +7 more
openaire   +5 more sources

Donor‐Specific Antibodies in Liver Transplantation [PDF]

Clinical Liver Disease, 2020
http://aasldpubs.onlinelibrary.wiley.com/hub/journal/10.1002/(ISSN)2046-2484/video/15-1-reading-nilles a video presentation of this article Answer questions and earn https://www.wileyhealthlearning.com/Activity/7025330/disclaimerspopup.aspx.
Kathy M, Nilles, Josh, Levitsky
  +10 more sources

Correlation between Luminex donor‐specific crossmatches and levels of donor‐specific antibodies in pretransplantation screening

Tissue Antigens, 2013
AbstractBefore kidney transplantation, recipients are routinely screened for preformed antibodies and prospective crossmatches. In this study, we compared prospective Luminex donor‐specific crossmatches (LumXm) with the levels of identified, donor‐specific antibodies (DSAs).
Guillaume, N., Mazouz, H., Piot, V., Presne, C., Westeel, P.‐f.   +4 more
openaire   +4 more sources

Impact of Donor-Specific anti-HLA antibodies and donor KIR characteristics in haploidentical HSCT for beta-Thalassemia [PDF]

Mediterranean Journal of Hematology and Infectious Diseases, 2017
In the present study we investigated the role of donor specific HLA antibodies (DSA) and donor KIR repertoire characteristics in a group of 18 patients affected by haemoglobinopathies who underwent haploidentical T cell depleted transplantation.
Marco Andreani, Manuela Testi, Pietro Sodani, Maria Troiano, Andrea Di Luzio, Giuseppe Testa, Michela Falco, Elvira Poggi, Javid Gaziev, Antonina Piazza   +9 more
doaj   +2 more sources