Successful treatment of refractory donor‐specific‐human leukocyte antigen‐antibody‐induced primary graft‐failure with daratumumab: A case report [PDF]
Donor‐specific anti‐human leukocyte antigen (HLA) antibodies represent a main cause of primary graft failure specifically in the setting of haploidentical stem cell transplantation.
Vadim Lesan +8 more
doaj +3 more sources
De Novo Donor-Specific Antibodies after Heart Transplantation: A Comprehensive Guide for Clinicians. [PDF]
Antibodies directed against donor-specific human leukocyte antigens (HLAs) can be detected de novo after heart transplantation and play a key role in long-term survival.
Marco I +9 more
europepmc +2 more sources
Immunology and Donor-Specific Antibodies in Corneal Transplantation [PDF]
AbstractThe first human corneal transplantation was performed in 1905 by Eduard Zirm in the Olomouc Eye Clinic, now Czech Republic. However, despite great advancements in microsurgical eye procedures, penetrating keratoplasty in high-risk patients (e.g., vascularized or inflamed corneal tissue, consecutive transplants) remains a challenge.
Joanna Major +3 more
openaire +2 more sources
Donor-Specific Antibodies Against Donor Human Leukocyte Antigen are Associated with Graft Inflammation but Not with Fibrosis Long-Term After Liver Transplantation: An Analysis of Protocol Biopsies [PDF]
Background: Donor-specific antibodies (DSA) against donor human leukocyte antigen after liver transplantation, which are associated with histological changes, have been widely studied with respect to their sustained impact on transplant function. However,
Öllinger, Robert +14 more
core +1 more source
Donor-Specific Antibodies—The Devil Is in the Detail [PDF]
No description ...
V. Carter, W. M. Howell, James Shaw
openaire +3 more sources
Complementing donor-specific antibody testing [PDF]
New data suggest that among kidney transplant recipients, those whose serum contains donor-specific antibodies that bind C1q fare the worst. Although these findings are intriguing, several unanswered questions remain and changing practice to include a C1q binding assay as standard of care in kidney transplantation would be premature.
Kathryn J, Tinckam, Peter S, Heeger
openaire +2 more sources
Detection of donor-specific antibodies in kidney transplantation [PDF]
Precise and timely detection of human leukocyte antigen (HLA) donor-specific antibodies (DSAs) is vital for evaluating humoral immune status of patients pre- and post-transplantation.Clinically relevant articles on theory, development, methodology and application of HLA-DSA testing in kidney transplantation.The availability of solid phase HLA-antibody ...
Kelley M K, Haarberg, Anat R, Tambur
openaire +2 more sources
Intragraft donor-specific antibodies and lung transplantation [PDF]
Intragraft DSA can be found in explanted lungs of patients with chronic lung allograft dysfunction in the absence of circulating DSA. New diagnostic approaches to assess for intragraft DSA may add to our diagnostic arsenal in treating AMR.http://bit.ly ...
Jussi M, Tikkanen, Kathryn, Tinckam
openaire +2 more sources
Graft failure is a major complication after unrelated cord blood transplantation. Presence of HLA-antibodies before cord blood transplantation may impact graft failure.
Annalisa Ruggeri +22 more
doaj +1 more source
Development of donor-specific human leukocyte antigen (HLA) antibodies (DSA) remains a major risk factor for graft loss following organ transplantation, where DSA are directed towards patches on the three-dimensional structure of the respective organ ...
Matthias Niemann +13 more
doaj +1 more source

