Results 21 to 30 of about 8,474,282 (288)

Successful treatment of refractory donor‐specific‐human leukocyte antigen‐antibody‐induced primary graft‐failure with daratumumab: A case report [PDF]

open access: yeseJHaem
Donor‐specific anti‐human leukocyte antigen (HLA) antibodies represent a main cause of primary graft failure specifically in the setting of haploidentical stem cell transplantation.
Vadim Lesan   +8 more
doaj   +3 more sources

De Novo Donor-Specific Antibodies after Heart Transplantation: A Comprehensive Guide for Clinicians. [PDF]

open access: yesJ Clin Med, 2023
Antibodies directed against donor-specific human leukocyte antigens (HLAs) can be detected de novo after heart transplantation and play a key role in long-term survival.
Marco I   +9 more
europepmc   +2 more sources

Immunology and Donor-Specific Antibodies in Corneal Transplantation [PDF]

open access: yesArchivum Immunologiae et Therapiae Experimentalis, 2021
AbstractThe first human corneal transplantation was performed in 1905 by Eduard Zirm in the Olomouc Eye Clinic, now Czech Republic. However, despite great advancements in microsurgical eye procedures, penetrating keratoplasty in high-risk patients (e.g., vascularized or inflamed corneal tissue, consecutive transplants) remains a challenge.
Joanna Major   +3 more
openaire   +2 more sources

Donor-Specific Antibodies Against Donor Human Leukocyte Antigen are Associated with Graft Inflammation but Not with Fibrosis Long-Term After Liver Transplantation: An Analysis of Protocol Biopsies [PDF]

open access: yes, 2021
Background: Donor-specific antibodies (DSA) against donor human leukocyte antigen after liver transplantation, which are associated with histological changes, have been widely studied with respect to their sustained impact on transplant function. However,
Öllinger, Robert   +14 more
core   +1 more source

Donor-Specific Antibodies—The Devil Is in the Detail [PDF]

open access: yesAmerican Journal of Transplantation, 2017
No description ...
V. Carter, W. M. Howell, James Shaw
openaire   +3 more sources

Complementing donor-specific antibody testing [PDF]

open access: yesNature Reviews Nephrology, 2013
New data suggest that among kidney transplant recipients, those whose serum contains donor-specific antibodies that bind C1q fare the worst. Although these findings are intriguing, several unanswered questions remain and changing practice to include a C1q binding assay as standard of care in kidney transplantation would be premature.
Kathryn J, Tinckam, Peter S, Heeger
openaire   +2 more sources

Detection of donor-specific antibodies in kidney transplantation [PDF]

open access: yesBritish Medical Bulletin, 2014
Precise and timely detection of human leukocyte antigen (HLA) donor-specific antibodies (DSAs) is vital for evaluating humoral immune status of patients pre- and post-transplantation.Clinically relevant articles on theory, development, methodology and application of HLA-DSA testing in kidney transplantation.The availability of solid phase HLA-antibody ...
Kelley M K, Haarberg, Anat R, Tambur
openaire   +2 more sources

Intragraft donor-specific antibodies and lung transplantation [PDF]

open access: yesEuropean Respiratory Journal, 2019
Intragraft DSA can be found in explanted lungs of patients with chronic lung allograft dysfunction in the absence of circulating DSA. New diagnostic approaches to assess for intragraft DSA may add to our diagnostic arsenal in treating AMR.http://bit.ly ...
Jussi M, Tikkanen, Kathryn, Tinckam
openaire   +2 more sources

Impact of donor-specific anti-HLA antibodies on graft failure and survival after reduced intensity conditioning-unrelated cord blood transplantation: a Eurocord, Société Francophone d’Histocompatibilité et d’Immunogénétique (SFHI) and Société Française de Greffe de Moelle et de Thérapie Cellulaire (SFGM-TC) analysis

open access: yesHaematologica, 2013
Graft failure is a major complication after unrelated cord blood transplantation. Presence of HLA-antibodies before cord blood transplantation may impact graft failure.
Annalisa Ruggeri   +22 more
doaj   +1 more source

Snowflake epitope matching correlates with child-specific antibodies during pregnancy and donor-specific antibodies after kidney transplantation

open access: yesFrontiers in Immunology, 2022
Development of donor-specific human leukocyte antigen (HLA) antibodies (DSA) remains a major risk factor for graft loss following organ transplantation, where DSA are directed towards patches on the three-dimensional structure of the respective organ ...
Matthias Niemann   +13 more
doaj   +1 more source

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