Results 251 to 260 of about 2,312,760 (293)
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Seminars in Nephrology, 2007
The introduction of both complement 4d (C4d) staining in renal allograft biopsies and sensitive methods to detect anti-human leukocyte antigen antibodies, such as single antigen bead flow assays, into tissue-typing techniques have shown the importance of antibody-mediated alloimmune response in kidney transplantation. The use of these sensitive methods,
Enver, Akalin, Bruno, Watschinger
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The introduction of both complement 4d (C4d) staining in renal allograft biopsies and sensitive methods to detect anti-human leukocyte antigen antibodies, such as single antigen bead flow assays, into tissue-typing techniques have shown the importance of antibody-mediated alloimmune response in kidney transplantation. The use of these sensitive methods,
Enver, Akalin, Bruno, Watschinger
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Antibody-Mediated Rejection and Lung Transplantation
Seminars in Respiratory and Critical Care Medicine, 2021AbstractAntibody-mediated rejection (AMR) is now a widely recognized form of lung allograft rejection, with mounting evidence for AMR as an important risk factor for the development of chronic lung allograft dysfunction and markedly decreased long-term survival.
Laura P, Halverson, Ramsey R, Hachem
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Antibody-Mediated Organ-Allograft Rejection
Nature Reviews Immunology, 2005Recent studies show that alloantibodies mediate a substantial proportion of graft-rejection episodes, contributing to both early and late graft loss. Rejection that is caused by antibody is mediated by different mechanisms from rejection that is caused by T cells, thereby requiring other approaches to treatment and prevention.
Robert B Colvin
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Emerging strategies for antibody-mediated rejection
Current Opinion in Organ Transplantation, 2022Purpose of the review Antibody-mediated rejection (AMR) is the leading cause of kidney graft loss. Very few treatment options are available to the clinician to counter this disease process. In this review we describe the available therapeutics and the novel approaches that are being currently developed.
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Antibody-Mediated rejection in the kidney
Transplantation Proceedings, 2004Antibody-mediated rejection is increasingly recognized as a cause of acute and chronic rejection in kidney as well as other organ allografts. New diagnostic criteria have been drafted to diagnose this entity and enable timely therapy.
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Cardiac antibody–mediated rejection
Pediatric Transplantation, 2012Chin C. Cardiac antibody–mediated rejection.Abstract: Many factors limit short‐ and long‐term survival after pediatric heart transplantation. Historically, attention had been directed toward T‐cell responses and acute cellular rejection. Presence of pretransplant antibodies against HLA is associated with increased donor wait times and poor post ...
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Pathological Features of Antibody-Mediated Rejection
Current Drug Target -Cardiovascular & Hematological Disorders, 2005Although cell-mediated rejection has remained the most common form of graft rejection after organ transplantation, antibody-mediated rejection has recently gained much significance in clinical transplantation. New evidence points to an antibody-mediated rejection contributing not only to hyperacute and acute but also to chronic allograft rejection.
Akira, Shimizu, Robert B, Colvin
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Management of Antibody-Mediated Rejection in Transplantation
Surgical Clinics of North America, 2013Despite intensive traditional immunosuppressive therapy, rates of graft loss have approximated 15% to 20% at 1 year following antibody-mediated rejection (AMR) in solid organ transplant recipients. Therefore, the development of antihumoral therapies that provide prompt elimination of donor-specific anti-HLA antibodies and improve allograft survival is ...
Basma, Sadaka +2 more
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New insights in antibody-mediated rejection
Current Opinion in Nephrology and Hypertension, 2014In the present review, we aim to describe the state of knowledge concerning antibody-mediated rejection (ABMR) spectrum and diagnosis criteria before analyzing the present and future promising leads regarding ABMR prognosis markers and treatment.Recent studies regarding complement-binding donor-specific antibodies and the molecular approach highlighted
Clément, Gosset +2 more
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Treatment of Acute Antibody-Mediated Rejection
2017Acute antibody-mediated rejection (AMR) remains an important challenge in the field of kidney transplantation despite the advances in immunosuppressive strategies, and has been recognized as an important cause of allograft dysfunction and graft loss.
COMAI, GIORGIA +9 more
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