Results 91 to 100 of about 2,528,348 (198)

Evaluation of a measles vaccine campaign by oral-fluid surveys in a rural Kenyan district: interpretation of antibody prevalence data using mixture models [PDF]

, 2009
We evaluated the effectiveness of a measles vaccine campaign in rural Kenya, based on oral-fluid surveys and mixture-modelling analysis. Specimens were collected from 886 children aged 9 months to 14 years pre-campaign and from a comparison sample of 598
Brown, D. W. G., Okiro, E. A., Were, S., Bett, A., Nokes, D. James, Gay, N. J., Vyse, A. J., Abwao, John, Ohuma, E. O., Samuel, Dhan   +9 more
core   +1 more source

Mutation N856K in spike reduces fusogenicity and infectivity of Omicron BA.1

Signal Transduction and Targeted Therapy, 2023
Chunyun Sun, Huiyu Wang, Ji Yang, Desheng Kong, Yuning Chen, Haiyue Wang, Lingling Sun, Jianbo Lu, Min Teng, Liangzhi Xie   +9 more
doaj   +1 more source

Lipid Metabolic Pathways Confer the Immunosuppressive Function of Myeloid-Derived Suppressor Cells in Tumor

Frontiers in Immunology, 2019
Myeloid-derived suppressor cells (MDSCs) play crucial roles in tumorigenesis and their inhibition is critical for successful cancer immunotherapy.
Dehong Yan, Adeleye O. Adeshakin, Adeleye O. Adeshakin, Meichen Xu, Meichen Xu, Lukman O. Afolabi, Lukman O. Afolabi, Guizhong Zhang, Youhai H. Chen, Xiaochun Wan, Xiaochun Wan   +10 more
doaj   +1 more source

Antibody targeted nanoparticles for imaging and therapy of cancer [PDF]

, 2010
The central hypothesis for this thesis is that antibody-targeted superparamagnetic iron oxide nanoparticles (SPIONs) can be used for diagnosis and therapy of cancer.
Vigor, K.L.
core  

Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer

Nature Communications, 2018
Native-like soluble HIV envelope (Env) trimers are potential vaccine immunogens, and elimination of furin-dependence could provide a DNA-based alternative. Here, Sarkar et al.
Anita Sarkar, Shridhar Bale, Anna-Janina Behrens, Sonu Kumar, Shailendra Kumar Sharma, Natalia de Val, Jesper Pallesen, Adriana Irimia, Devan C. Diwanji, Robyn L. Stanfield, Andrew B. Ward, Max Crispin, Richard T. Wyatt, Ian A. Wilson   +13 more
doaj   +1 more source

Highly sensitive quantification of human total VEGF-A with a novel ELISA

Bone Reports, 2020
Andreea Ana-Maria Suciu, Elisabeth Gadermaier, Jacqueline Wallwitz, Gabriela Berg, Gottfried Himmler   +4 more
doaj   +1 more source

Author Correction: A Rift Valley fever mRNA vaccine elicits strong immune responses in mice and rhesus macaques

npj Vaccines, 2023
Ting Bian, Meng Hao, Xiaofan Zhao, Chuanyi Zhao, Gang Luo, Zhendong Zhang, Guangcheng Fu, Lu Yang, Yi Chen, Yudong Wang, Changming Yu, Yilong Yang, Jianmin Li, Wei Chen   +13 more
doaj   +1 more source

From discovery to the clinic: structural insights, engineering options, clinical, and ‘next wave’ applications of camelid-derived single-domain antibodies

mAbs
Camelid-derived single domain antibodies (sdAbs), referred to as VHHs (variable domains of the heavy chain of a heavy chain-only antibodies), recently emerged as promising building blocks for the construction of therapeutic molecules. As of October 2025,
Andreas Evers, Enrico Guarnera, Lukas Pekar, Stefan Zielonka   +3 more
doaj   +1 more source

Influence of Acyclovir on Antibody Production of Antibody to Chickenpox [PDF]

, 2003
Titers of immunoglobulin (Ig) G and 1gM antibody to varicella zoster virus (VZV) were measured in 20 pediatric patients with chickenpox during treatment with acyclovir, an antiviral agent. Acyclovir doses, each 80 mg/kg/day, were administered for 5 days,
Tsuji, Atsutoshi, Tsuchiya, Takayoshi, Nagaoka, Yuuko, Nagai, Toshiro   +3 more
core   +1 more source

Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining

Nature Communications
We describe a process for rapid antibody affinity optimization by repertoire mining to identify clones across B cell clonal lineages based on convergent immune responses where antigen-specific clones with the same heavy (VH) and light chain germline ...
Yi-Chun Hsiao, Heidi Ackerly Wallweber, Robert G. Alberstein, Zhonghua Lin, Changchun Du, Ainhoa Etxeberria, Theint Aung, Yonglei Shang, Dhaya Seshasayee, Franziska Seeger, Andrew M. Watkins, David V. Hansen, Christopher J. Bohlen, Peter L. Hsu, Isidro Hötzel   +14 more
doaj   +1 more source