Results 81 to 90 of about 2,528,348 (198)

Antibody and Antibody Mimetic Immunotherapeutics [PDF]

Future Medicinal Chemistry, 2017
Angeline N, Ta, Brian R, McNaughton
openaire   +2 more sources

Shikonin inhibits NLRP3 inflammasome activation and controls inflammatory disease

Scientific Reports
Shikonin (SHK) is a plant-derived naphthoquinone known for its anti-inflammatory activity, though the mechanism remains largely unexplored. The NLRP3 inflammasome, one of the most studied inflammasomes, can cause uncontrolled inflammation and drive ...
Jing Huang, Mengmeng Dai, Xinyu Huang, Wenqing Qi, Jing Jing, Jiayi He, Zhizhuo Lu, Chaofang Zhang, Guiling Wang, Run Cao, Yuanfang Ma, Hailong Zhang   +11 more
doaj   +1 more source

Rapid isolation of pan-neutralizing antibodies against Omicron variants from convalescent individuals infected with SARS-CoV-2

Frontiers in Immunology
IntroductionThe emergence of SARS-CoV-2 Omicron subvariants has presented a significant challenge to global health, as these variants show resistance to most antibodies developed early in the pandemic.
Peng Yu, Jingping Ran, Jingping Ran, Ruiqi Yang, Hang Zhu, Song Lu, Yuzhang Wu, Tingting Zhao, Tingting Zhao, Tianchen Xiong   +9 more
doaj   +1 more source

CLEC14a-HSP70-1A interaction regulates HSP70-1A-induced angiogenesis

Scientific Reports, 2017
CLEC14a (C-type lectin domain family 14 member) is a tumor endothelial cell marker protein that is known to play an important role in tumor angiogenesis, but the basic molecular mechanisms underlying this function have not yet been clearly elucidated. In
Jihye Jang, Mi Ra Kim, Taek-Keun Kim, Woo Ran Lee, Jong Heon Kim, Kyun Heo, Sukmook Lee   +6 more
doaj   +1 more source

Long-lived antibody and B Cell memory responses to the human malaria parasites, Plasmodium falciparum and Plasmodium vivax. [PDF]

, 2010
Antibodies constitute a critical component of the naturally acquired immunity that develops following frequent exposure to malaria. However, specific antibody titres have been reported to decline rapidly in the absence of reinfection, supporting the ...
Thaikla, Kanitta, Riley, Eleanor M, Julius Clemence R Hafalla, Cook Jackie, Lucy C Okell, Eleanor M Riley, Suphavilai Chaisuree, Lucy C. Okell, Witaya Liewsaree, Okell, Lucy C, Liewsaree, W, Corran Patrick H., Hafalla Julius Clemence R., Cook, Jackie, Corran, Patrick H, Kanitta Thaikla, Cook, J, Patrick H. Corran, Hafalla, Julius Clemence R, Chaisuree Suphavilai, Wipasa, J, Suphavilai, C, Okell Lucy C., Riley Eleanor M., Jackie Cook, Wipasa Jiraprapa, Julius Clemence R. Hafalla, Liewsaree, Witaya, Suphavilai, Chaisuree, Thaikla, K, Eleanor M. Riley, Patrick H Corran, Hafalla, JC, Thaikla Kanitta, Wipasa, Jiraprapa, Okell, LC, Riley, EM, Corran, PH, Liewsaree Witaya, Jiraprapa Wipasa   +39 more
core   +1 more source

Death by antibody

BMJ Case Reports, 2019
A 42-year-old woman with a background of psoriatic arthritis presented with a 7-day medical history of fevers of unknown source; she had recently undergone elective shoulder arthroscopy, and her medications included anti-interleukin 17A (anti-IL-17A) drug, secukinumab.
Timothy Faccini, Zaneeta Dhesi, Sachin Shah   +2 more
openaire   +3 more sources

Antibody-Catalysis of a Bimolecular Asymmetric 1,3-Dipolar Cycloaddition Reaction [PDF]

, 2016
Antibody-Catalysis of a Bimolecular Asymmetric 1,3-Dipolar Cycloaddition ...
Yunfeng Hu (2255629), Paul Wentworth, (2668996), Jonathan D. Toker (2668999), K. N. Houk (1247004), Kim D. Janda (163029)   +4 more
core   +1 more source

Generation and application of recombinant antibody fragments for prostate cancer detection. [PDF]

, 2010
Prostate cancer (PCa) is the most prevalent adenocarcinoma and the second highest cause of cancer-related deaths in men. Early diagnosis is required to identify the development of PCa to reduce the risk of the disease metastasising to different regions ...
Hayes, Conor
core  

Antibody-Bridged DNAzyme Walker for Sensitive Detection of Small Molecules [PDF]

Sensitive detection of small molecules with biological and environmental interests is important for many applications, such as food safety, disease diagnosis, and environmental monitoring.
Qiang Zhao (105948), Han Pang (18340646)
core   +1 more source

Diminished but Not Abolished Effect of Two His351 Mutants of Anthrax Edema Factor in a Murine Model

Toxins, 2016
Edema toxin (ET), which is composed of a potent adenylate cyclase (AC), edema factor (EF), and protective antigen (PA), is one of the major toxicity factors of Bacillus anthracis.
Taoran Zhao, Xinghui Zhao, Ju Liu, Yingying Meng, Yingying Feng, Ting Fang, Jinlong Zhang, Xiuxu Yang, Jianmin Li, Junjie Xu, Wei Chen   +10 more
doaj   +1 more source