Results 61 to 70 of about 2,528,348 (198)

Human monoclonal antibody combination against SARS coronavirus : synergy and coverage of escape mutants [PDF]

, 2006
Background: Experimental animal data show that protection against severe acute respiratory syndrome coronavirus (SARS-CoV) infection with human monoclonal antibodies (mAbs) is feasible.
Peiris, Joseph S. M., Cox Freek, Doerr, Hans Wilhelm, Brink, Edward van den, van den Brink Edward N, Hans Wilhelm Doerr, ter Meulen Jan, Doerr Hans Wilhelm, Cheung, Chung Y., de Kruif John, van Deventer, Els, Jaap Goudsmit, Leo L. M., Poon, Leo L M Poon, Marissen Wilfred E, Marissen, Wilfred E., Poon Leo L. M, van den Brink, Edward N., Chow Vincent T, Chung Y Cheung, Wolfgang Preiser, Leung, Cynthia S.W., Preiser, Wolfgang, Van Deventer, E, Bogaards Johannes A, Freek Cox, Wilfred E Marissen, Els van Deventer, Joseph S M Peiris, Chow, Tak-Kwong Vincent, Bakker, Arjen Q., Leung, CSW, Chow, Vincent T., de Kruif, John, Goudsmit Jaap, ter Meulen, Jan, Deventer, Els van, Kruif, John de, De Kruif, J, John de Kruif, Cynthia S W Leung, Jan ter Meulen, Bogaards, Johannes A., Cox, F, Preiser Wolfgang, Cox, Freek, Goudsmit, J, Peiris Joseph S. M, Poon, LLM, Cheung, CY, Johannes A Bogaards, Doerr, HW, van Deventer Els, Marissen, WE, Bakker Arjen Q, Peiris, Joseph S.M., Poon, Leo L. M., Leung Cynthia S. W, Chow, VT, Edward N van den Brink, Bogaards, JA, Vincent T Chow, Arjen Q Bakker, Poon, Leo L.M., Cheung Chung Y, Van Den Brink, EN, Peiris, Joseph Sriyal Malik, Ter Meulen, J, Leung, Cynthia S. W., Goudsmit, Jaap, Peiris, JSM, Meulen, Jan ter, Bakker, AQ, Preiser, W   +73 more
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Immunogenicity of monovalent and multivalent subunit vaccines against SARS-CoV-2 variants in mice with divergent vaccination history

Microbiology Spectrum
There are challenges in selecting SARS-CoV-2 vaccine compositions, primarily due to divergent infection or vaccination history and immunological biases toward previous strains. In this study, we evaluated humoral immune responses induced by variant-based
Rui Wang, Yuan Lyu, Meng Chen, Lili Sun, Shaozheng Zhou, Yudi Cui, Juan Ma, Desheng Kong, Jianbo Lu, Xuefeng Li, Liangzhi Xie   +10 more
doaj   +1 more source

Tetanus Neurotoxin Neutralizing Antibodies Screened from a Human Immune scFv Antibody Phage Display Library

Toxins, 2016
Tetanus neurotoxin (TeNT) produced by Clostridium tetani is one of the most poisonous protein substances. Neutralizing antibodies against TeNT can effectively prevent and cure toxicosis.
Han Wang, Rui Yu, Ting Fang, Ting Yu, Xiangyang Chi, Xiaopeng Zhang, Shuling Liu, Ling Fu, Changming Yu, Wei Chen   +9 more
doaj   +1 more source

Epstein-Barr virus but not cytomegalovirus is associated with reduced vaccine antibody responses in Gambian infants. [PDF]

, 2010
BACKGROUND: Epstein-Barr virus (EBV) and cytomegalovirus (CMV) are persistent herpesviruses that have various immunomodulatory effects on their hosts. Both viruses are usually acquired in infancy in Sub-Saharan Africa, a region where childhood vaccines ...
Ebrima S Touray, Whittle, H., Miles David J. C., Kaye, Steve, Melba S Palmero, Roberts, E., Ojuola, Olubukola, Miles, DJ, Palmero Melba S., Ojuola, O, Kaye Steve, Duah, NO, Mohammed, N.I., Cotten, M., Marianne van der Sande, Waight Pauline, Rowland-Jones, S., van der Sande, M, Cotten, M, Touay, Ebrima S., Holder, B., Cotten Matthew, Mohammed, NI, van der Sande Marianne, Whittle, H, Crozier, Sarah, Roberts, Elishia, Rowland-Jones, Sarah, Crozier, S., Miles, David J.C., Palmero, Melba S., Ojuola Olubukola, Waight, P., Touray, ES, Beth Holder, Roberts Elishia, Nuredin Ibrahim Mohammed, Nancy O Duah, Sarah Crozier, Touray, E.S., Hilton Whittle, Mohammed, Nuredin Ibrahim, Elishia Roberts, Sarah Rowland-Jones, Ebrima S. Touray, Touray, Ebrima S, van der Sande, M., Nancy O. Duah, Matthew Cotten, Whittle Hilton, Miles, David J C, Steve Kaye, Miles, David JC, van der Sande, Marianne, Kaye, S, Ojuola, O., David J C Miles, Mohammed Nuredin Ibrahim, Holder Beth, Palmero, M.S., Duah Nancy O., Melba S. Palmero, Cotten, Matthew, Duah, Nancy O, Palmero, Melba S, Whittle, Hilton, Miles, DJC, Rowland-Jones Sarah, Miles, D.J., Kaye, S., Holder, B, Olubukola Ojuola, David J. C. Miles, Touray Ebrima S., Duah, Nancy O., Palmero, MS, Duah, N.O., Waight, Pauline, Roberts, E, Rowland-Jones, S, Holder, Beth, Waight, P, Crozier, S, Pauline Waight, Crozier Sarah   +84 more
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Antibodies in milk [PDF]

Reproduction, 1982
Introduction Both in clinical practice and in the scientific literature human milk is often treated as though its only important properties were the volume in which it is produced and its nutritional composition in terms of fat, carbohydrate and protein content.
openaire   +2 more sources

Single scaffold antibody libraries created with high rates of mutagenesis or diversity focused for peptide recognition [PDF]

, 2007
textThis dissertation describes several strategies used to create diversity in non-immune antibody libraries. Two of the strategies were used to create two separate peptide focused libraries.
Cobaugh, Christian Wessel, 1971-
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Acquisition of antibody isotypes against Plasmodium falciparum blood stage antigens in a birth cohort. [PDF]

, 2010
Information on the period during which infants lose their maternally derived antibodies to malaria and begin to acquire naturally their own immune responses against parasite antigens is crucial for understanding when malaria vaccines may be best ...
Duah, NO, D. J. C. MILES, Conway, DJ, N. O. DUAH, Whittle, HC, H. C. WHITTLE, D. J. CONWAY, Miles, DJC   +7 more
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A novel bispecific antibody targeting CD3 and prolactin receptor (PRLR) against PRLR-expression breast cancer

Journal of Experimental & Clinical Cancer Research, 2020
Background Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe but with poor efficacy.
Yuexian Zhou, Huifang Zong, Lei Han, Yueqing Xie, Hua Jiang, John Gilly, Baohong Zhang, Huili Lu, Jie Chen, Rui Sun, Zhidi Pan, Jianwei Zhu   +11 more
doaj   +1 more source

A study of antibody secretion from hybridoma cells [PDF]

, 1988
The secretion of monoclonal antibody in both batch and continuous cultures was studied. It was found that when hybridoma cells were continuously cultivated in a simple lab scale fermenter, they secreted less antibody than cells grown in stationary ...
Holland, P.N.
core  

Virus-neutralizing monoclonal antibody expressed in milk of transgenic mice provides full protection against virus-induced encephalitis [PDF]

, 2001
Neutralizing antibodies represent a major host defense mechanism against viral infections. In mammals, passive immunity is provided by neutralizing antibodies passed to the offspring via the placenta or the milk as immunoglobulin G and secreted ...
Pewe, L, John Webster, Whitelaw, C B, Andreas F. Kolb, Perlman, S, Siddell, S G, Stanley Perlman, C. Bruce A. Whitelaw, Stuart G. Siddell, Webster, J, Kolb, A F, Lecia Pewe   +11 more
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