Results 121 to 130 of about 4,988,508 (434)
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
CLEC14a-HSP70-1A interaction regulates HSP70-1A-induced angiogenesis
Scientific Reports, 2017 CLEC14a (C-type lectin domain family 14 member) is a tumor endothelial cell marker protein that is known to play an important role in tumor angiogenesis, but the basic molecular mechanisms underlying this function have not yet been clearly elucidated. In
Jihye Jang +6 more
doaj +1 more source
SARS CoV subunit vaccine: Antibodymediated neutralisation and enhancement [PDF]
, 2012 1. A SARS vaccine was produced based on recombinant native full-length Spike-protein trimers (triSpike) and efficient establishment of a vaccination procedure in rodents. 2.
Altmeyer, R +14 more
core +1 more source
Antibody-Mediated Encephalitis.
New England Journal of Medicine, 2018 Antibody-Mediated Encephalitis The category of autoimmune encephalitides constitutes disorders with relatively distinct characteristics such as psychosis, seizures, abnormal movements, coma, and dysautonomia.
J. Dalmau, F. Graus
semanticscholar +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen. [PDF]
, 2018 Anti-carbohydrate monoclonal antibodies (mAbs) hold great promise as cancer therapeutics and diagnostics. However, their specificity can be mixed, and detailed characterization is problematic, because antibody-glycan complexes are challenging to ...
Amon, Ron +12 more
core +2 more sources
Antibody Detection and Dynamic Characteristics in Patients with COVID-19
Clinical Infectious Diseases, 2020 Background The corona virus disease 2019 (COVID-19) caused by the corona virus 2 (SARS-CoV-2) has been rapidly spreading nationwide and abroad. A serologic test to identify antibody dynamics and response to SARS-CoV-2 was developed.
Fei-Xiang Xiang +12 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Microgravimetric immunosensor for direct detection of aerosolized influenza A virus particles. [PDF]
, 2007 The development and characterization of a quartz crystal microbalance (QCM) sensor for the direct detection of aerosolized influenza A virions is reported.
Al-Kaysi, Rabih O +3 more
core
Science immunology, 2020 Illness severity in COVID-19 correlates with specificity of serological responses, but antibody levels decrease in most patients. SARS-CoV-2-specific antibodies, particularly those preventing viral spike receptor binding domain (RBD) interaction with ...
K. Röltgen +29 more
semanticscholar +1 more source