Results 211 to 220 of about 3,844,696 (336)

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Impaired systemic antibody response against gut microbiota pathobionts in critical illness and susceptibility to nosocomial infections. [PDF]

Intensive Care Med Exp
Cho NA, Schlechte J, Yu IL, Bains I, Fahlman T, Mackenzie C, McDonald B.   +6 more
europepmc   +1 more source

Efficacy of the double-antibody sandwich EIA in CHIKV diagnosis.

Kun Wen (790021), Zhihong Zhou (353166), Peipei Xu (391804), Biao Di (284801), Jialing Song (15283367), Cuilian Yang (22784181), Lili Zhan (22784184), Chongquan Zhao (22784187), Mei Xu (188070), Jianpiao Cai (9857938), Shuofeng Yuan (2827973), Kelvin Kai-Wang To (9144227), Wenxi Feng (15304580), Jasper Fuk-Woo Chan (8085932), Hongwei Zhou (93199), Yue Chen (73753), Xixia Ding (567730)   +16 more
openalex   +1 more source

Context-dependent genomic locus effects on antibody production in recombinant Chinese hamster ovary cells generated through random integration [PDF]

Hyun Jee Woo, Jae‐Hoon Kim, Seul Mi Kim, Dong‐Woo Kim, Jae Yun Moon, Daechan Park, Jae Seong Lee   +6 more
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Incidence and clinical relevance of donor-derived recipient-specific anti-HLA antibodies in haploidentical hematopoietic stem cell transplantation: a retrospective study. [PDF]

Cell Transplant
Huang X, Ren Y, Wang S, Mei C, Xu Y, Jin J, Tong H, Qian J.   +7 more
europepmc   +1 more source

Hantavirus antibody positivity in febrile patients.

Devinda S. Muthusinghe (9300285), Pavani Senarathne (21526734), Kenta Shimizu (2095999), Yomani D. Sarathkumara (21526737), Shanika Nanayakkara (13845748), Sithumini M.W. Lokupathirage (21526740), Zhouoxing Wei (21526743), Nipun S. Rathnayake (21526746), Rydhnieya Vijeyakumaran (21526749), Nobuo Koizumi (276538), Tomonori Kawakami (2942679), Akio Koizumi (65151), Kouji H. Harada (213306), Nilanthi Dissanayake (6680327), Senanayake A. M. Kularathne (21526752), Yoshimi Tsuda (210505), Shuzo Urata (32561), Jiro Arikawa (10906536), Chandika D. Gamage (6680324), Kumiko Yoshimatsu (9300288)   +19 more
openalex   +1 more source

USE OF INTRAVENOUS IMMUNOGLOBULIN WITHIN THE IVF/ICSI PROTOCOL IN WOMEN WITH INFERTILITY AND ANTIPHOSPHOLIPID ANTIBODIES

, 2017
M. I. Krivonos, М. С. Зайнулина, Ekaterina A. Kornyushina, S. V. Chepanov, S. А. Selkov   +4 more
openalex   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source