Results 261 to 270 of about 5,128,022 (309)
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Antiphospholipid antibodies and the antiphospholipid antibody syndrome
Drugs of Today, 2000The antiphospholipid antibody syndrome is a multisystem disorder characterized by persistently elevated antiphospholipid antibodies and/or arterial or venous thrombosis, thrombocytopenia and recurrent spontaneous abortion. Anticardiolipin antibodies and the lupus anticoagulant are different classes of antiphospholipid antibodies associated with this ...
Jensen Sl, Nahass Gt
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Computational Analysis of Antibody Paratopes for Antibody Sequences in Antibody Libraries
2022To ensure the functionalities of the antibodies in phage-displayed synthetic antibody libraries, we use computational method to evaluate the designs of the antibody libraries. The computational methodologies developed in our lab for designing antibody library provide rich information on the function of the designed antibody sequences-adequate antibody ...
Hung-Pin, Peng, An-Suei, Yang
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Antiphospholipid antibody and antiphospholipid antibody syndrome
Current Opinion in Rheumatology, 1991New details have been added to the description of the antiphospholipid antibody syndrome. These include quantitation of risk of stroke; delineation of an associated acute occlusive vasculopathy syndrome, including its pathology; increased awareness of the association of adrenal insufficiency with antiphospholipid antibody; new demonstration of ...
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Current Opinion in Chemical Biology, 1998
Following the end of the first decade in catalytic antibody research, recent efforts are reflecting a more introspective view of the field. Notably, X-ray crystal structure analyses of antibody catalysts are permitting an increased understanding of the evolution and modus operandi of these remarkable biocatalysts. Additionally, the breadth and scope of
P, Wentworth, K D, Janda
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Following the end of the first decade in catalytic antibody research, recent efforts are reflecting a more introspective view of the field. Notably, X-ray crystal structure analyses of antibody catalysts are permitting an increased understanding of the evolution and modus operandi of these remarkable biocatalysts. Additionally, the breadth and scope of
P, Wentworth, K D, Janda
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Antibody structure and antibody engineering
Advanced Drug Delivery Reviews, 1988Abstract Immunoglobulin (Ig) genes are efficiently expressed following transfection into myeloma cells. The heavy and light chain genes, cloned into two compatible plasmids with different selectible markers, can be delivered simultaneously into the same cell.
Lee K. Tan, Sherie L. Morrison
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Antiacetylcholinesterase antibodies: Enzyme antibodies interaction
Pharmacological Research Communications, 1981Summary Erythrocyte acetylcholinesterase activity of rabbits was significantly increased over control levels by immunization with acetylcholinesterase from the electric organ of the electric eel. The increase of enzyme activity and that of anti-acetylcholinesterase antibodies had the same time course, reaching a maximum level on the 35th day.
B. Conti-Tronconi +3 more
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Journal of Clinical Oncology, 1998
PURPOSE The CD20 antigen is expressed on more than 90% of B-cell lymphomas. It is appealing for targeted therapy, because it does not shed or modulate.
P. Mclaughlin +15 more
semanticscholar +1 more source
PURPOSE The CD20 antigen is expressed on more than 90% of B-cell lymphomas. It is appealing for targeted therapy, because it does not shed or modulate.
P. Mclaughlin +15 more
semanticscholar +1 more source
From antibodies to sperm to antibodies in transplantation
Urology, 1998a) To assess the use of "panning" procedures for the detection of antibodies to sperm. b) To develop and use human monoclonal antibodies for the analysis of human transplantation antigens."Panning" assays were developed. The procedures and their use in the analysis of mouse monoclonal antibodies to human sperm are described.
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Veterinary Microbiology, 2006
Herpesviruses have developed different tools to thwart efficient antibody-dependent neutralisation and lysis of virions and elimination of infected cells. This overview will briefly summarize different of these tools, including (i) viral Fc receptors and the resulting process of antibody bridging, (ii) internalization of individual viral proteins and ...
Hans Nauwynck +4 more
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Herpesviruses have developed different tools to thwart efficient antibody-dependent neutralisation and lysis of virions and elimination of infected cells. This overview will briefly summarize different of these tools, including (i) viral Fc receptors and the resulting process of antibody bridging, (ii) internalization of individual viral proteins and ...
Hans Nauwynck +4 more
openaire +3 more sources
2001
A method of identifying at least one consensus sequence for an intracellular antibody (ICS) comprising the steps of: creating a database comprising sequences of validated intracellular antibodies (VIDA database) and aligning the sequences of validated intracellular antibodies according to Kabat; determining the frequency with which a particular amino ...
CATTANEO, ANTONINO +4 more
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A method of identifying at least one consensus sequence for an intracellular antibody (ICS) comprising the steps of: creating a database comprising sequences of validated intracellular antibodies (VIDA database) and aligning the sequences of validated intracellular antibodies according to Kabat; determining the frequency with which a particular amino ...
CATTANEO, ANTONINO +4 more
openaire +5 more sources