Antibody numbering schemes: advances, comparisons and tools for antibody engineering. [PDF]
Zhu Z +6 more
europepmc +1 more source
Enhancing full-length antibody production by signal peptide engineering [PDF]
Yizhou Zhou +7 more
openalex +1 more source
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash +6 more
wiley +1 more source
Integrating Biochemical and Computational Approaches Reveal Structural Insights in Trastuzumab scFv-Fc Antibody Engineering. [PDF]
Bednova O +9 more
europepmc +1 more source
A Fast and Sensitive Luciferase-based Assay for Antibody Engineering and Design of Chimeric Antigen Receptors. [PDF]
Natarajan V +9 more
europepmc +1 more source
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda +9 more
wiley +1 more source
Modelling the influence of foot-and-mouth disease vaccine antigen stability and dose on the bovine immune response [PDF]
Charleston, B +7 more
core +1 more source
Antibody engineering and phage display technology [PDF]
Dmitri Dormeshkin
openalex +1 more source
Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan–Targeting Antibodies without the Need for Immune Effector Cells or Complement [PDF]
Mireille Vankemmelbeke +12 more
openalex +1 more source

