Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Efficacy of Accelerated Vaccination against Hbv to Achieve Antibody formation in Multiple Sclerosis Patients Receiving Anti-Cd20 Therapy. [PDF]
Ann Indian Acad Neurol, 2023 Koc ER +5 more
europepmc +1 more source
Ampk regulates IgD expression but not energy stress with B cell activation. [PDF]
, 2019 Ampk is an energy gatekeeper that responds to decreases in ATP by inhibiting energy-consuming anabolic processes and promoting energy-generating catabolic processes.
Ahsan, Fasih M +9 more
core +1 more source
Studies on the Adjuvant Action of Bacterial Endotoxins on Antibody Formation [PDF]
, 1959 Phyllis D. Kind, Arthur G. Johnson
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Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Effects of the complement system on antibody formation and function: implications for transplantation. [PDF]
Curr Opin Organ Transplant, 2022 Cumpelik A, Heeger PS.
europepmc +1 more source
Characterizing the zebrafish organizer: microsurgical analysis at the early-shield stage [PDF]
, 1996 The appearance of the embryonic shield, a slight thickening at the leading edge of the blastoderm during the formation of the germ ring, is one of the first signs of dorsoventral polarity in the zebrafish embryo.
Fraser, Scott E., Shih, John
core
IMMUNITY IN DIABETES. III. RELATION OF TISSUE GLYCOGEN AND BLOOD CHEMISTRY TO BACTERIAL DISSEMINATION, ANTIBODY FORMATION AND SURVIVAL AFTER INFECTION IN DIABETES [PDF]
, 1940 Russell S. Richardson
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Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Oral tolerance to prevent anti-drug antibody formation in protein replacement therapies. [PDF]
Cell Immunol, 2022 Rana J, Muñoz MM, Biswas M.
europepmc +1 more source