Results 231 to 240 of about 7,305,993 (392)

Antibiotic use differentially affects the risk of anti-drug antibody formation during anti-TNFα therapy in inflammatory bowel disease patients: a report from the epi-IIRN. [PDF]

Gut, 2022
Gorelik Y, Freilich S, Gerassy-Vainberg S, Pressman S, Friss C, Blatt A, Focht G, Weisband YL, Greenfeld S, Kariv R, Lederman N, Dotan I, Geva-Zatorsky N, Shen-Orr SS, Kashi Y, Chowers Y, IIRN.   +16 more
europepmc   +1 more source

Tissue‐Level Mechanisms Responsible for the Increase in Bone Formation and Bone Volume by Sclerostin Antibody

Journal of Bone and Mineral Research, 2014
M. Ominsky, Qing‐Tian Niu, Chaoyang Li, Xiaodong Li, H. Ke   +4 more
semanticscholar   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Platelet spleen tyrosine kinase is a key regulator of anti-PF4 antibody–induced immunothrombosis

Blood Advances
: Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but serious prothrombotic adverse event after vaccination with adenovector-based COVID-19 vaccines.
Jan Zlamal, Vera M. Ripoll, Christine S.M. Lee, Filip Toma, Karina Althaus, Flavianna Rigoni, Andreas Witzemann, Shane Whittaker, David Capraro, Günalp Uzun, Tamam Bakchoul, Vivien M. Chen   +11 more
doaj  

The Effect of Immunologically Induced Lymphopenia on Antibody Formation [PDF]

, 1969
John Baum, George Liebermann, Eugene P. Frenkel   +2 more
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Tofacitinib to prevent anti-drug antibody formation against LMB-100 immunotoxin in patients with advanced mesothelin-expressing cancers. [PDF]

Front Oncol
Skorupan N, Peer CJ, Zhang X, Choo-Wosoba H, Ahmad MI, Lee MJ, Rastogi S, Sato N, Yu Y, Pegna GJ, Steinberg SM, Kalsi SS, Cao L, Figg WD, Trepel JB, Pastan I, FitzGerald D, Alewine C.   +17 more
europepmc   +1 more source

Inhibition of Antibody Formation by Homologous Tissue Factors [PDF]

, 1965
Richard Thompson, C. W. Fishel
openalex   +1 more source

Decreased clinical response to adalimumab in ankylosing spondylitis is associated with antibody formation

Annals of the Rheumatic Diseases, 2009
M. K. D. Vries, Elisabeth Brouwer, I. Horst-Bruinsma, A. Spoorenberg, J. C. Denderen, A. Jamnitski, M. Nurmohamed, B. Dijkmans, Lucien Aarden, G. Wolbink   +9 more
semanticscholar   +1 more source