Results 221 to 230 of about 670,787 (298)

Naturally acquired antibodies to <i>Plasmodium vivax</i> Pv_LISP-2, a potential liver stage vaccine antigen. [PDF]

Front Immunol
Donassolo RA, Soares da Veiga GT, Nisimura LM, Bittencourt NC, Salazar YEAR, Barros DKADS, Lopes SCP, de Sousa TN, Costa FTM, Albrecht L.   +9 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Blu-Ray-Based Quantification of CD98+ Extracellular Vesicles for Early Detection of Hepatocellular Carcinoma. [PDF]

Cancers (Basel)
Chen SL, Low YS, Huang BR, Lu CH, Lan WC, Wu RH, Lin HY, Yueh A, Hsu EC.   +8 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Progressive multifocal leukoencephalopathy - a diagnostic guide for the clinical neurologist. [PDF]

Front Neurol
Jia DT.
europepmc   +1 more source

Peroxidase antibody test for mucocutaneous leishmaniasis serology. Performance indexes and comparison with a fluorescent antibody test.

Revista do Instituto de Medicina Tropical de Sao Paulo, 1989
B J, Celeste, C S, Guimarães, E M, Corrales   +2 more
openaire   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

The role of the FT3/FT4 ratio in predicting remission and relapse in pediatric Graves' disease. [PDF]

Eur J Pediatr
Kara L, Siraz UG, Cicek D, Sarikaya E, Gok E, Berber U, Kendirci M, Kurtoğlu S, Hatipoglu N.   +8 more
europepmc   +1 more source