Results 131 to 140 of about 2,253,953 (246)

Engineered immunostimulatory H2O2‐producing microreactors driven by yeast as localized living cancer therapeutics

BMEMat, EarlyView.
Engineered yeast microreactors that produce H2O2 within tumors enable selective cancer cell killing while releasing immunostimulatory components, effectively suppressing local tumor growth and activating systemic antitumor immunity, with further efficacy enhanced by anti‐PD‐1 therapy and transarterial embolization.
Wenqian He, Chunjie Wang, Minming Chen, Weihao Yang, Bin Yu, Yuhang Hu, Hengze Ding, Yifan Yan, Zhijuan Yang, Liangzhu Feng   +9 more
wiley   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Impact of Transient and Persistent Donor-Specific Antibodies in Lung Transplantation

Transplant International
Lung transplantation (LuTx) is an established treatment for patients with end-stage lung diseases, however, outcomes are limited by acute and chronic rejection.
S. Auner, C. Hillebrand, P. M. Boehm, J. Boecker, D. Koren, S. Schwarz, Z. Kovacs, G. Murakoezy, G. Fischer, C. Aigner, K. Hoetzenecker, P. Jaksch, A. Benazzo   +12 more
doaj   +1 more source

Review of articular cartilage repair techniques and their application in the horse

Equine Veterinary Journal, EarlyView.
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton, Brad B. Nelson, Laurie R. Goodrich   +2 more
wiley   +1 more source

Zbtb7a induction in alveolar macrophages is implicated in anti-HLA–mediated lung allograft rejection

, 2017
Zbtb7a in alveolar macrophages influences early inflammation and autoimmunity in antibody-mediated rejection of transplanted lungs.
Ramsey Hachem, Jing Huang, Thalachallour Mohanakumar, Min Xu, Michael A. Smith, Fangyu Zhou, Ross M. Bremner, Deepak K. Nayak, Andrew E. Gelman, Jinsheng Yu, Moriya Tsuji   +10 more
core   +1 more source

Composition of allogeneic equine orthobiologics and their repeated intra‐articular administrations

Equine Veterinary Journal, EarlyView.
Abstract Background Orthobiologics such as platelet‐rich plasma (PRP) and alpha‐2‐macroglobulin (A2MG) are increasingly used for equine musculoskeletal injuries. However, their composition and safety with repeated allogeneic intra‐articular administration remain poorly investigated.
Yanne Van Reusel, Sarah Y. Broeckx, Anna Carolo, Marco Patruno, Jonas Steenbrugge, Jimmy Saunders, Enrico Gugliandolo, Jan H. Spaas   +7 more
wiley   +1 more source

The histological development of acute antibody-mediated rejection in HLA antibody-incompatible renal transplantation

, 2009
Background. The aim of this study was to examine the development of acute antibody-mediated rejection in HLA antibody-incompatible renal transplantation in relation to the Banff 07 histological classification. Methods.
Briggs, David, Imray, C. (Chris), Lam, For T., Fletcher, Simon, McKinnell, Joanna, Krishnan, Nithya, Chen, Klaus, Lowe, David Philip, Hamer, Rizwan, Zehnder, Daniel, Kashi, Habib, Higgins, Rob, Tan, Lam Chin, D. Zehnder, R. Higgins, F. T. Lam, L. C. Tan, H. Kashi, J. McKinnell, R. Hamer, S. Fletcher, D. Lowe, C. Imray, D. Briggs, N. Krishnan, K. Chen   +25 more
core   +1 more source

Hydrogel‐Based Bioelectronics: From Therapy and Sensing to Neuromorphic Computation

FlexTech, EarlyView.
This review establishes a material–conduction–property–application framework connecting hydrogel chemistry and charge transport with therapy, sensing, closed‐loop feedback, and neuromorphic computation. ABSTRACT Bioelectronics establish bidirectional communication between living systems and electronic devices, providing an enabling platform for ...
Jianlong Hong, Jiaqi Lu, Yijun Hao, Ning Ren, Shuhan He, Haobo Qi, Jingfeng Xu, Chengkuo Lee   +7 more
wiley   +1 more source

The Treatment of Acute Antibody-Mediated Rejection: Current State and Future Perspectives

Despite the advances in the immunosuppressive therapies and improvements in short term allograft survival, Antibody-mediated rejection (AMR) still represents the leading cause of late allograft failure in kidney transplant recipients.
Maggiore U., Fiaccadori E., Benigno G. D., Gandolfini I., Delsante M., Gentile M., Palmisano A., D'angelo M.   +7 more
core  

Advancing super‐resolution stimulated emission depletion microscopy with luminescent lanthanide nanocrystals

FlexMat, EarlyView.
The state‐of‐the‐art research advances and its cutting‐edge application in super resolution stimulated emission depletion technology based on luminescent lanthanide nanocrystals. Abstract Stimulated emission depletion (STED) microscopy overcomes the diffraction limit to reveal subcellular structures beyond the reach of conventional optical methods ...
Yaqi Chen, Tengfei Ma, Shuping Huang, Wei Guo, Yiming Wu   +4 more
wiley   +1 more source