Results 11 to 20 of about 2,053,658 (355)

Inheritance of Antibody Response [PDF]

open access: bronzeAustralian Journal of Biological Sciences, 1955
The heritability of antibody response to sheep red cells (S.R.C.) was found to be 0 2836 0 1475 at 3 days and 0 1097 0 1165 at 6 days. These estimates are subject to environmental variation of measurement which was found subsequently but could not be corrected for.
WR Sobey, KM Adams
openalex   +3 more sources

Epigenetics of the antibody and autoantibody response [PDF]

open access: yesCurrent Opinion in Immunology, 2020
B cell differentiation driven by microbial antigens leads to production of anti-microbial antibodies, such as those neutralizing viruses, bacteria or bacterial toxin, that are class-switched (IgG and IgA) and somatically hypermutated (maturation of the antibody response) as well as secreted in large volume by plasma cells. Similar features characterize
Justin B Moroney   +4 more
openaire   +3 more sources

Epigenetics of the antibody response [PDF]

open access: yesTrends in Immunology, 2013
Epigenetic marks, such as DNA methylation, histone post-translational modifications and miRNAs, are induced in B cells by the same stimuli that drive the antibody response. They play major roles in regulating somatic hypermutation (SHM), class switch DNA recombination (CSR), and differentiation to plasma cells or long-lived memory B cells.
Hong Zan   +3 more
openaire   +3 more sources

Potent and Persistent Antibody Response in COVID-19 Recovered Patients

open access: yesFrontiers in Immunology, 2021
SARS-CoV-2 has caused a global pandemic with millions infected and numerous fatalities. Virus-specific antibodies can be detected in infected patients approximately two weeks after symptom onset.
Xiaodong Tian   +12 more
doaj   +1 more source

Göttingen Minipigs as a Model to Evaluate Longevity, Functionality, and Memory of Immune Response Induced by Pertussis Vaccines

open access: yesFrontiers in Immunology, 2021
Evaluation of the short-term and long-term immunological responses in a preclinical model that simulates the targeted age population with a relevant vaccination schedule is essential for human vaccine development.
Céline Vaure   +5 more
doaj   +1 more source

CXCR5+CD8+ T Cells Shape Antibody Responses In Vivo Following Protein Immunisation and Peripheral Viral Infection

open access: yesFrontiers in Immunology, 2021
Crosstalk between T and B cells is crucial for generating high-affinity, class-switched antibody responses. The roles of CD4+ T cells in this process have been well-characterised.
Timona S. Tyllis   +9 more
doaj   +1 more source

A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity [PDF]

open access: yes, 2020
Malaria is a global health concern and research efforts are ongoing to develop a superior vaccine to RTS,S/AS01. To guide immunogen design, we seek a comprehensive understanding of the protective humoral response against Plasmodium falciparum ...
Bosch, A.   +15 more
core   +2 more sources

The association between life events, social support, and antibody status following thymus-dependent and thymus-independent vaccinations in healthy young adults [PDF]

open access: yes, 2005
This study determined whether stressful life events and social support were related to antibody status following both thymus-dependent and thymus-independent vaccinations. Life events in the previous year and customary social support were measured in 57
Burns, Victoria E.   +4 more
core   +1 more source

ZBTB38 is dispensable for antibody responses

open access: yesPLOS ONE, 2020
Members of the broad complex, tram track, bric-a-brac and zinc finger (BTB-ZF) family of transcription factors, such as BCL-6, ZBTB20, and ZBTB32, regulate antigen-specific B cell differentiation, plasma cell longevity, and the duration of antibody production.
Deepta Bhattacharya   +2 more
openaire   +5 more sources

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