Results 191 to 200 of about 1,478,450 (299)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Broad neutralizing antibody response of a monomeric spike-based SARS-CoV-2 bivalent vaccine against diverse variants. [PDF]

Proc Natl Acad Sci U S A
Wang S, Sun H, Wang Y, Wang Z, Yuan L, Guo H, Gao J, Lan M, Wu Y, Shang H, Chen X, Chen Z, Hu J, Tang Z, Wen G, Ying D, Liu C, Jiang Y, Su J, Lin M, Wu T, Li S, Zhang T, Zhang J, Guan Y, Xia N, Yuan Q, Zheng Q, Zhang Y, Zheng Z.   +29 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Targeting Langerhans cells via skin delivery of HIV Envelope enhances the antibody response to vaccination. [PDF]

NPJ Vaccines
Lanza JS, Hammoudi A, De Chiara J, Surenaud M, Kembou A, Esposito M, Zurawski S, Zurawski G, Centlivre M, Malissen B, Godot V, Lévy Y, Henri S, Cardinaud S.   +13 more
europepmc   +1 more source

Adjuvanting an inactivated influenza vaccine with flagellin improves the function and quantity of the long-term antibody response in a nonhuman primate neonate model

, 2016
Beth C. Holbrook, Ralph B. D’Agostino, Griffith D. Parks, Martha A. Alexander‐Miller   +3 more
openalex   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Neutralizing antibody response to different COVID-19 vaccines in Brazil: the impact of previous infection and booster doses. [PDF]

Front Immunol
Caetano BLL, Pinto PBA, Pacheco AR, Lage AR, Pereira ASG, Nascimento AVP, Machado TR, Paulino A, Medeiros TL, Fernandes-Siqueira LO, Da Poian AT, Horbach IS, Azevedo AS, Costa SM, Alves AMB.   +14 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Mapping the antibody response to Lassa virus vaccination of non-human primates. [PDF]

EBioMedicine
Enriquez AS, Avalos RD, Parekh D, Cooper CL, Morrow G, Geisbert TW, Parks CL, Hastie KM, Saphire EO.   +8 more
europepmc   +1 more source

Vaccination of rhesus macaques with the live-attenuated HSV-1 vaccine VC2 stimulates the proliferation of mucosal T cells and germinal center responses resulting in sustained production of highly neutralizing antibodies

, 2016
Brent Stanfield, Bapi Pahar, Vladimir N. Chouljenko, Ronald S. Veazey, Konstantin G. Kousoulas   +4 more
openalex   +1 more source