Results 231 to 240 of about 2,053,658 (355)

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Pulmonary function and comparative SARS-CoV-2 RBD-specific IgG antibody response among the COVID-19 recovered group. [PDF]

PLoS One
Siddik AB, Faisal A, Khan AH, Alam MMM, Nayeem J, Kulsum U, Mukta SA, Kawser Z, Hasan I, Azad K, Hossain M, Kar S, Sultana N, Alam MR, Mustafa A, Habib MT, Ryan ET, Qadri F, Hassan MR.   +18 more
europepmc   +1 more source

Antibody Responses in Rabbits to the Group B Arbovirus Kunjin: Serologic Activity of the Fractionated Immunoglobulins in Homologous and Heterologous Reactions [PDF]

, 1968
E. G. Westaway
openalex   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Pig nasal and rectal microbiotas are involved in the antibody response to Glaesserella parasuis. [PDF]

Sci Rep
Obregon-Gutierrez P, Mahmmod Y, Barba-Vidal E, Sibila M, Correa-Fiz F, Aragón V.   +5 more
europepmc   +1 more source

The Heterogeneity of Combining Sites of Anti-Benzylpenicilloyl Antibodies Obtained from Individual Rabbits: Changes in Combining Sites of γG and γM Antibodies During the Immune Response [PDF]

, 1968
Tsuyoshi Atsumi, Masaaki Adachi, Yoshio KINOSHITA, Morio Kawasaki, Yoshihiko Horiuchi   +4 more
openalex   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Investigating SARS-CoV-2 Neutralising Antibody Response in Sheep. [PDF]

Microorganisms
Samojlović M, Mesquita JR, Santos-Silva S, Neptin M, Esbjörnsson J.   +4 more
europepmc   +1 more source

The specificity of the antibody responses of human volunteers to certain respiratory viruses [PDF]

, 1964
F. E. Buckland, Jennifer E. Doggett, D. A. J. Tyrrell   +2 more
openalex   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

FEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh, Esther Lee, Soo‐A Kim   +2 more
wiley   +1 more source