Results 181 to 190 of about 969,569 (304)
Identification of antibody specificity using adsorption-elution studies with incompatible packed red cell unit. [PDF]
Nivedita K +5 more
europepmc +1 more source
Analysis of Histone Antibody Specificity with Peptide Microarrays. [PDF]
Cornett EM, Dickson BM, Rothbart SB.
europepmc +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
HLA class I peptide polymorphisms contribute to class II DQβ0603:DQα0103 antibody specificity. [PDF]
Shih NR +10 more
europepmc +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
An Interactive Database for the Assessment of Histone Antibody Specificity. [PDF]
Rothbart SB +12 more
europepmc +1 more source
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
A novel method for antibody specificity identification using microscale direct antiglobulin test-positive red cells. [PDF]
Zhang Y, Xiang D.
europepmc +1 more source

