Results 201 to 210 of about 10,319,593 (322)

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Elementary immunology [PDF]

, 2017
Gogolák, Péter, Koncz, Gábor
core  

HLA class I peptide polymorphisms contribute to class II DQβ0603:DQα0103 antibody specificity. [PDF]

Nat Commun
Shih NR, Nong T, Murphey C, Lopez-Cepero M, Nickerson PW, Taupin JL, Devriese M, Nilsson J, Matignon MB, Bray RA, Lee JH.   +10 more
europepmc   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection

Science, 2016
Karin Stettler, M. Beltramello, Diego A. Espinosa, Victoria A. Graham, Antonino Cassotta, S. Bianchi, Fabrizia Vanzetta, A. Minola, S. Jaconi, F. Mele, Mathilde Foglierini, M. Pedotti, L. Simonelli, S. Dowall, B. Atkinson, E. Percivalle, C. Simmons, L. Varani, J. Blum, F. Baldanti, E. Cameroni, R. Hewson, E. Harris, A. Lanzavecchia, F. Sallusto, D. Corti   +25 more
semanticscholar   +1 more source

A novel method for antibody specificity identification using microscale direct antiglobulin test-positive red cells. [PDF]

Blood Transfus
Zhang Y, Xiang D.
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Clinical severity in adult warm autoimmune hemolytic anemia and its relationship to antibody specificity. [PDF]

Haematologica, 2018
Chadebech P, Loustau V, Janvier D, Languille L, Ripa J, Tamagne M, Bierling P, Djoudi R, Godeau B, Michel M, Pirenne F, Mahévas M.   +11 more
europepmc   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Reconciling specificity and non-specificity in antibody binding: an energy landscape framework for immunology education

Frontiers in Immunology
Zhiyong Wang, Jiaqi Li, Min Wang, Yan Yu, Yanxin Lu, Qiang Xia, Pei Wei   +6 more
doaj   +1 more source